Cat. No. | Product name | CAS No. |
DC65592 |
AChE-IN-30
Featured
AChE-IN-30 is an AChE inhibitor. |
2937454-22-1 |
124608 |
EN450
Featured
EN450 is a cysteine-reactive covalent molecular glue degrader targeting NF-κB. |
793719-01-4 |
DC65594 |
Anticancer agent 129
Featured
Anticancer agent 129 (Compound 3a), a quinoline derivative, predicting to has anti-cancer activity. |
135882-37-0 |
DC65605 |
WAY-299359
Featured
WAY-299359 is a FLT3 inhibitor |
1005057-81-7 |
DC65606 |
WAY-304800-A
Featured
WAY-304800-A is a Casein kinase 1δ inhibitor. |
345616-08-2 |
DC65607 |
WAY-311474
Featured
WAY-311474 altering the lifespan of eukaryotic organisms. |
569313-77-5 |
DC65608 |
WAY-625135
Featured
WAY-625135 is a Casein kinase 1δ inhibitor. |
756865-45-9 |
DC65609 |
WAY-646458
Featured
WAY-646458 is a Casein kinase 1d inhibitor. |
852413-92-4 |
DC65610 |
WAY-270250
Featured
WAY-270250 is a IGF-1R/SRC inhibitor. |
852367-46-5 |
DC65611 |
WAY-299562
Featured
WAY-299562 is a modulator of the interaction of protein kinase A (PKA) and A kinase anchor proteins (AKAP). |
299934-88-6 |
DC65612 |
Lenalidomide-acetylene-Br
Featured
Lenalidomide-acetylene-Br is a PROTAC Linker that makes up HJM-561. |
2619512-84-2 |
DC65613 |
LZWL02003
Featured
LZWL02003 is a neuroprotective agent and derivative of N-salicyloyl tryptamine. LZWL02003 upregulated the expression of Bcl-2 and downregulated the expression of Bax, thus maintaining the homeostasis of Bcl-2/Bax proteins and preventing apoptosis. LZWL02003 also reduced oxidative stress by reducing malondialdehyde and reactive oxygen species levels, increasing the superoxide dismutase activity, and resolving mitochondrial malfunction. LZWL02003 can lower interleukin (IL)-1β, tumor necrosis factor (TNF)-α, and IL-6 levels, which in turn suppress neuroinflammation. LZWL02003 suppressed the phosphorylation activation of NF-κB pathway-related proteins and decreased the nuclear translocation of NF-κB p65 subunits. LZWL02003 is a neuroprotective agent with pleiotropic effects and may be a candidate for treating cerebral I/R injury. |
1371564-45-2 |
DC65614 |
AJ2-30
Featured
AJ2-30 is a SLCl5A4 inhibitor. |
2700322-79-6 |
DC65615 |
AJ2-71
Featured
AJ2-71 is a SLCl5A4 inhibitor. |
2700323-17-5 |
DC65616 |
JC-229
Featured
JC-229 is a TbRPA1 inhibitor. JC-229 targets RPA1 in Trypanosoma brucei, the causative parasite of African trypanosomiasis. JC-229 is highly toxic to T. brucei cells, while mildly toxic to human cells. JC-229 treatment mimics the effects of TbRPA1 depletion, including DNA replication inhibition and DNA damage accumulation. JC-229 inhibits the activity of TbRPA1, but not the human ortholog. |
|
DC65617 |
TH-Z93
Featured
TH-Z93, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 90 nM). |
2260887-09-8 |
DC60492 |
244-cis
Featured
244-cis is an ionizable, liver-specific lipid. 244-cis LNP that induces lower immune responses than the responses evoked by previously used LNPs. 244-cis LNP and low-dose adeno-associated virus could minimize side effects and achieve a therapeutic threshold in hemophilia A mice. |
|
DC60493 |
BEBT-809
Featured
BEBT-809 is a GPR75 antagonist for rat CYP4F2 and CYP4A11 with IC50 of and 15.76 nM and 33.16 nM, respectively. |
|
DC60494 |
76-O17Se
Featured
76-O17Se is a lipidoid for the efficient delivery of antiCD19 mRNA CAR to murine primary macrophages. 76-O17Se is more efficient than delivery with lipofectamine 2000 (LPF2K) or MC3 |
|
DC60495 |
9322-O16B
Featured
9322-O16B is a lipidoid for the efficient delivery of antiCD19 mRNA CAR to murine primary macrophages. LNP 9322-O16B is more efficient than delivery with lipofectamine 2000 (LPF2K) or MC3. |
2909427-23-0 |
DC65618 |
DSPE-NHS
Featured
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as drug nanocarrier. |
1383932-86-2 |
DC65619 |
LNP Lipid-8
Featured
LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model. |
2408140-60-1 |