| DC7934 |
L-006,235
Featured
|
L 006235 is a reversible and potent cathepsin K inhibitor that displays more than a 4000 fold selectivity over cathepsins B, L and S. |
|
| DC8578 |
L002(NSC764414)
Featured
|
L002 is a p300 inhibitor (IC50=1.98 μM) that inhibits p53 and histone acetylation. Suppresses STAT3 activation in vitro and suppresses tumor growth in some mouse cell lines. |
|
| DC2076 |
L-165041
Featured
|
L-165041 is a potent PPARδ agonist (Ki = 6 nM). |
|
| DC8136 |
L-189
Featured
|
L-189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 μM respectively) that blocks DNA binding (Ki = 5 μM for DNA ligase I). |
|
| DC20041 |
L-5-Hydroxytryptophan (L-5-HTP; Oxitriptan)
Featured
|
L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. L-5-Hydr |
|
| DC8790 |
L67
Featured
|
L67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM. |
|
| DC8615 |
L-685,458
Featured
|
L-685,458 is a selective and Potent inhibitor of γ-secretase with IC50 value of 17 nM. |
|
| DC8159 |
L-701,324
Featured
|
L-701,324 is a selective antagonist at the glycine site of the NMDA receptor, counteracts haloperidol-induced muscle rigidity in rats. |
|
| DC8092 |
L-755,507
Featured
|
L-755,507 enhances CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs). |
|
| DC8803 |
L-778123 HCl
Featured
|
L-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and 98 nM in enzyme inhibition determination. |
|
| DC8362 |
L-779,450
Featured
|
L-779,450 is a potent, ATP-competitive Raf (Raf kinase) inhibitor (IC50 = 10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively. |
|
| DC8797 |
Lacosamide
Featured
|
Lacosamide (Vimpat; Erlosamide) is a medication developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. |
|
| DC1108 |
Laninamivir (CS-8958)
Featured
|
Laninamivir (CS-8958) is a neuraminidase inhibitor which is being researched for the treatment and prophylaxis of Influenzavirus A and Influenzavirus B. |
|
| DC23858 |
Lanraplenib (GS-9876)
Featured
|
Lanraplenib is a potent, selective Syk kinase inhibitor for treatment various disease states, including cancer and inflammatory conditions. |
|
| DC23502 |
L-AP4
Featured
|
L-AP4 is a selective group III metabotropic glutamate receptor agonist.. |
|
| DCAPI1512 |
Lapatinib
Featured
|
Lapatinib |
|
| DC3143 |
Lapatinib ditosylate
Featured
|
Lapatinib Ditosylate (GW572016, GW2016, Tykerb, Tyverb) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively. |
|
| DC2071 |
ABR-215062 (Laquinimod)
Featured
|
Laquinimod (ABR-215062) is a potent immunomodulator. |
|
| DC7710 |
Lasmiditan (COL-144; LY573144)
Featured
|
Lasmiditan (COL-144; LY573144) is a high-affinity, highly selective 5-HT1F receptor agonist(Ki=2.1 nM), compared with Ki of 1043 nM and 1357 nM at the 5-HT(1B) and 5-HT(1D) receptors, respectively. |
|
| DCAPI1501 |
Lasofoxifene tartrate
Featured
|
Lasofoxifene Tartrate is a non-steroidal selective estrogen receptor modulator (SERM). |
|
| DC12443 |
LASV inhibitor 3.3
Featured
|
LASV inhibitor 3.3 (LAMP1 inhibitor 3.3) is a specific inhibitor of Lassa fever virus (LASV, IC50=1.8 uM), inhibits LASV GP-mediated infection and cross-links to the LASV receptor, LAMP1, in cells; does not inhibits the GP-mediated infection of LCMV, LuJo |
|
| DC8635 |
Latanoprost
Featured
|
Latanoprost is a prodrug (isopropyl ester) of 17-phenyl-13,14-dihydro prostaglandin F2α. |
|
| DC12188 |
Lathosterol
Featured
|
Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis. |
|
| DC10853 |
LAU159
Featured
|
LAU159 is a novelα6β3γ2 GABAA receptor inhibitor. |
|
| DC10598 |
lavendustin A
Featured
|
Lavendustin A is a selective inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase (IC50 = 11 nM) that was first isolated from a Streptomyces culture filtrate. |
|
| DC10597 |
lavendustin B
Featured
|
Lavendustin B is a Tyrosine Kinase Inhibitor amd an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75). |
|
| DC9512 |
Lazabemide
Featured
|
Lazabemide(Ro 19-6327/000) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
|
|
| DC11900 |
Lazertinib
Featured
|
Lazertinib (YH25448, GNS-1480) is a highly potent, mutant-selective, irreversible, brain-penetrant and orally active EGFR tyrosine-kinase inhibitors for both the T790M mutation and activating EGFR mutations |
|
| DC7801 |
LB-100
Featured
|
LB-100 is a small-molecular protein phosphatase 2A(PP2A)inhibitor with IC50 of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells. |
|
| DC22765 |
LB-102
Featured
|
LB-102 (LB-1.2, LB 102) is a a selective dopamine D2/3/5-HT7 inhibitor. |
|
