| DC5052 |
Lersivirine（UK 453061）
Featured
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Lersivirine (UK-453061) is a next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for the treatment of HIV-1 infection. |
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| DC8731 |
Lesinurad sodium
Featured
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Lesinurad sodium (RDEA594 sodium) is an once-daily inhibitor of URAT1; URAT1 is a transporter in the kidney that regulates uric acid excretion from the body. |
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| DC7631 |
Lesinurad (RDEA594）
Featured
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Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney that regulates uric acid excretion from the body. |
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| DC22807 |
Lestaurtinib
Featured
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Lestaurtinib (KT-5555, CEP-701) is a potent, orally active JAK2, FLT3 and TrkA inhibitor with IC50 of 0.9 nM, 3 nM and < 25 nM, respectively. |
|
| DC9798 |
Leteprinim
Featured
|
Leteprinim (Neotrofin, AIT-082) is a hypoxanthine derivative drug with neuroprotective and nootropic effects. |
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| DCAPI1414 |
Letrozole
Featured
|
Letrozole(CGS-20267) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant. |
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| DC9953 |
Leukadherin-1
Featured
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Leukadherin-1 is a specific agonist of CR3 and the leukocyte surface integrin CD11b/CD18. |
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| DC8688 |
Leupeptin hemisulfate
Featured
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Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor, which has been shown to inhibit cathepsins B, H, L, and S, calpain, and trypsin. Leupeptin hemisulfate is an orally active, antioxidant and anti-inflammatory agent. |
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| DC8314 |
Leuprolide Acetate
Featured
|
Leuprolide acetate (Leuprorelin) is a GnRH analog; leuprolide acetate acts as an agonist at pituitary GnRH receptors. |
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| DC22504 |
Leuprorelin
Featured
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Leuprorelin (Leuprolide) is a GnRH analog and agonist of GnRH receptor, interrupts the normal pulsatile stimulation and desensitizing of the GnRH receptors.. |
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| DC8714 |
Levobetaxolol hydrochloride
Featured
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Levobetaxolol hydrochloride is a beta-adrenergic receptor inhibitor (beta blocker), used to lower the pressure in the eye in treating conditions such as glaucoma. |
|
| DC12384 |
LF3
Featured
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LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 with an IC50 less than 2 μM. |
|
| DC22137 |
LGD2226
Featured
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LGD-2226 (LGD2226) is an orally active, selective androgen receptor modulator (SARM) with binding Ki of 1 nM, >1000-fold selectivity over GR,PR, MR and ER. |
|
| DC7633 |
Ligandrol (VK5211, LGD-4033)
Featured
|
Ligandrol (LGD-4033) is a novel nonsteroidal, oral SARM that binds to androgen receptor with high affinity (Ki of 1 nM) and selectivity. |
|
| DC10278 |
LGD-6972
Featured
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LGD-6972 is a selective and orally active glucagon receptor antagonist. LGD-6972 has the potential for type 2 diabetes research. |
|
| DC7186 |
LGK-974
Featured
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LGK-974 is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM. |
|
| DC7018 |
LGX-818(Encorafenib)
Featured
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LGX818 is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity. |
|
| DC10147 |
LH-21
Featured
|
LH 21 is a 1,2,4-triazole that acts as a cannabimimetic. |
|
| DC7454 |
LH846
Featured
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LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); displays no inhibitory activity at CK2. |
|
| DC12206 |
L-Hexanoylcarnitine
Featured
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L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease. |
|
| DC26014 |
Lifitegrast sodium
Featured
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Lifitegrast sodium, also known as SAR-1118, is an LFA-1 antagonist intended for the treatment of vascular complications of the eye. |
|
| DC23065 |
Ligustilide
Featured
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Ligustilide possesses neuroprotective, vasorelaxation, antinociceptive and anti-inflammatory activities, it blocked the activation of MAPKs/IKK and the downstream transcription factors AP-1 and NF-κB. |
|
| DC21915 |
LIN28 inhibitor LI71
Featured
|
LIN28 inhibitor LI71 is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 7 uM, binds the cold shock domain to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells. . |
|
| DC1105 |
Linagliptin (BI-1356)
Featured
|
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. |
|
| DC23026 |
Linderane
Featured
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Linderane is a mechanism-based inactivator of CYP2C9. |
|
| DC6905 |
Linezolid (PNU-100766)
Featured
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Linezolid (Zyvox) is a synthetic antibiotic used for the treatment of serious infections. |
|
| DC10820 |
Roquinimex(Linomide)
Featured
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Linomide is an Immunomodulator; anti-angiogenic. |
|
| DC9188 |
Liothyronine sodium
Featured
|
Liothyronine sodium (T3 Sodium sal) is the most potent form of thyroid hormone used to treat hypothyroidism and myxedema coma. |
|
| DC11011 |
Lipofermata
Featured
|
Lipofermata (CB16.2 aka) is a specific fatty acid transport (FATP) inhibitor, blocks human FATP2-mediated fatty acid uptake (IC50=4.84 uM in Caco-2 cells) without impacting other cellular functions. |
|
| DC7920 |
Liproxstatin-1
Featured
|
Liproxstatin-1 is able to suppress ferroptosis in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage. |
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