Cat. No. | Product name | CAS No. |
DC10447 |
FX1
Featured
FX1 is a novel specific inhibitor of the B cell lymphoma 6 (BCL6). |
1426138-42-2 |
DC21229 |
FX-11
Featured
FX-11 (LDHA inhibitor FX11) is a cell permeable, selective, reversible, NADH competitive inhibitor of lactate dehydrogenase A (LDHA) with Ki of 50 nM (LDHA subunit M), less potent for LDHB or pLDH. |
213971-34-7 |
DC8222 |
G007-LK
Featured
G007-LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor. |
1380672-07-0 |
DC24027 |
STING Agonist-1(G-10)
Featured
G10 (STING Agonist 1) is a novel human-specific STING agonist. |
702662-50-8 |
DC10814 |
G-15
Featured
G-15 is a cell-permeable non-steroidal antagonist of GPER (Ki = 20 nM). |
1161002-05-6 |
DC10501 |
G1T28(Trilaciclib)
Featured
G1T28(Trilaciclib) is a potential first-in-class, short-acting IV CDK4/6 inhibitor being developed to preserve hematopoietic stem cells and enhance immune system function during chemotherapy. |
1374743-00-6 |
DC10816 |
G-36
Featured
G-36 is a cell-permeable non-steroidal antagonist of GPER, inhibiting activation by either 17β-estradiol or the GPER-selective agonist G-1(IC50 = 112 and 165 nM, respectively). |
1392487-51-2 |
DC12438 |
G6PD activator AG1
Featured
G6PD activator AG1 (AG1) is a specific, small molecule that increases the activity of the wild-type, Canton mutant (R459L, EC50=3 uM) and several other common G6PD mutants; displays no effect on the dimerization or activity of several other NAD- or NADP+-dependent dimeric or tetrameric enzymes, including 6PGD, GAPDH, ALDH2, and ALDH3A1; attenuates ROS-induced pericardial edema in a G6PD-dependent manner in zebrafish, reduces hemolysis of human erythrocytes |
421581-52-4 |
DC7792 |
G-749
Featured
G-749 is an inhibitor of Fms-like tyrosine receptor kinase 3 (FLT3) with IC50 values ranging from 2.1 to 38.1 nM for wild-type and mutant (constitutively active) FLT3s in Ba/F3 cells expressing recombinant receptors. |
1457983-28-6 |
DC8954 |
Gabapentin
Featured
Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain. |
60142-96-3 |
DCAPI1037 |
Gadodiamide (Omniscan)
Featured
Gadodiamide is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Target: OthersGadodiamide(Omniscan) is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Gadodiamide is a contrast medium for cranial and spinal magnetic resonance imaging (MRI) and for general MRI of the body after intravenous administration. The product provides contrast enhancement and facilitates visualisation of abnormal structures or lesions in various parts of the body including the central nervous system (CNS). A recent review takes the question of toxicity caused by loss of gadolinium from the complex. "The challenge for nephrologists includes (a) evidence of transmetallation, such as gadolinium deposits in bone, increased urinary zinc excretion, iron-transferrin dissociation or 'spurious hypocalcemia' in exposed people"。 |
122795-43-1 |
DC11053 |
GAK inhibitor 49
Featured
GAK inhibitor 49 is a potent, selective, ATP-competitive inhibitor of cyclin G-associated kinase (GAK, cell IC50=56 nM) with favourable NAK family selectivity (AAK1, STK16, BMP2K). |
319492-82-5 |
DC9859 |
GAL-021
Featured
GAL-021 is a new intravenous BKCa-channel blocker. |
1380341-99-0 |
DC7861 |
(-)-Narwedine
Featured
Galantamine(Narwedin) is a competitive and reversible cholinesterase(AChE) inhibitor. |
510-77-0 |
DC10133 |
Gambogic Acid
Featured
Gambogic Acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-xl, Bcl-2, Bcl-w, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM, respectively. |
2752-65-0 |
DC21197 |
Ganaplacide
Featured
Ganaplacide (KAF156, GNF-156) is a novel antimalarial clinical candidate that shows blood schizonticidal activity with IC50 of 6-17.4 nM against P falciparum drug-sensitive and drug-resistant strains. |
1261113-96-5 |
DC7320 |
Ganetespib(STA-9090)
Featured
Ganetespib(STA-9090) is a unique triazolone-containing Hsp90 inhibitor with an IC50 of 4 nM in OSA 8 cells. |
888216-25-9 |
DC8877 |
Ganirelix
Featured
Ganirelix is a man-made form of a protein that reduces the amount of certain hormones in the body, including estrogen. |
124904-93-4 |
DC7129 |
GANT61(NSC 136476)
Featured
GANT 61(NSC 136476) is a small molecule inhibitor of Gli1 and Gli2. |
500579-04-4 |
DC20388 |
GAPDS
Featured
GAPDS is a small molecule that targets the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH). |
917773-99-0 |
DC26031 |
Gardiquimod trifluoroacetate
Featured
Gardiquimod trifluoroacetate is a specific TLR7 agonist which can also inhibit HIV-1 reverse transcriptase. |
1159840-61-5 |
DC12671 |
Gboxin
Featured
Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. |
2101315-36-8 |