DC42202 |
α-Terpinene |
α-Terpinene (Terpilene) is a monoterpene found in the essential oils of a large variety of foods and aromatic plants such as Mentha piperita. α-Terpinene is active against Trypanosoma evansi and has the potential for trypanosomosis treatment. α-Terpinene has antioxidant and antifungal properties. |
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DC42203 |
Triflumizole |
Triflumizole is one of imidazole fungicides that works by inhibiting ergosterol biosynthesis, and is widely used for the control of powdery mildew and scabs on various fruits and crops. |
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DC42269 |
Robinetin |
Robinetin (3,3',4',5',7-Pentahydroxyflavone) is a flavonoid that has antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant activity. Robinetin also can inhibit lipid peroxidation and protein glycosylation. |
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DC42270 |
Thalifoline |
Thalifoline is an alkaloid isolated from the New Caledonian plant Cryptocarya longifolia and displays antifungal activity. |
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DC41172 |
Butoconazole |
Butoconazole, an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole is presumed to function as other imidazole derivatives via inhibition of steroid synthesis. |
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DC42479 |
Pyrimethanil |
Pyrimethanil is an effective broad-spectrum fungicide often used for the prevention of Botrytis cinerea. Pyrimethanil inhibits methionine biosynthesis and other amino acids, thereby affecting protein formation and cell division. |
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DC42480 |
Fosravuconazole L-lysine ethanolate
Featured
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Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate), a prodrug of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used for candidiasis, onychomycosis and parasitemia research. |
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DC43981 |
Heneicosane |
Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. Heneicosane is a pheromone and inhibits aflatoxin production. |
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DC43982 |
Enfumafungin
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Enfumafungin, a triterpene glycoside, is isolated from extracts derived from an endophytic species of Hormonema. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis[1][2]. |
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DC43983 |
Papyracillic acid |
Papyracillic acid, a fungal metabolite, a Penicillic acid analog, is a nonselective herbicide. Papyracillic acid has anti-bacterial, anti-fungal, nematicidal, and phytotoxic effects. |
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DC44035 |
(-)-Bornyl acetate |
(-)-Bornyl acetate (L-(-)-Bornyl acetate), isolated from hyssop oil, is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate possesses antifungal activity. |
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DC44036 |
4-Methylcinnamic acid |
4-Methylcinnamic acid, a Cinnamic acid analog, can be used as a intervention catalyst for overcoming antifungal tolerance. 4-Methylcinnamic acid can improve the potency of cell wall-disrupting agents. |
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DC44079 |
Methyl p-coumarate |
Methyl p-coumarate (Methyl 4-hydroxycinnamate), an esterified derivative of p-Coumaric acid (pCA), is isolated from the flower of Trixis michuacana var longifolia. Methyl p-coumarate could inhibit the melanin formation in B16 mouse melanoma cells. Methyl p-coumarate also has strong in vitro inhibitory effect on A. alternata and other pathogens. |
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DC44113 |
Ibrexafungerp citrate
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Ibrexafungerp citrate is a triterpenoid antifungal. Similarly to echinocandins, it inhibits the synthesis of 1,3-β-d-glucan. However, it binds to a different site on the enzyme than echinocandins, resulting in limited cross-resistance. Ibrexafungerp exerts concentration-dependent fungicidal activity against Candida species and retains in vitro activity against most fluconazole-resistant strains. |
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DC44114 |
Pyribencarb
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Pyribencarb is a benzylcarbamate-type fungicide, which is active against a wide range of plant pathogenic fungi. Pyribencarb is a potent Qo inhibitor of cytochrome b. Pyribencarb is especially active against Botrytis cinerea and Sclerotinia sclerotirum. |
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DC44115 |
1-Dodecylimidazole |
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity. |
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DC44536 |
Neticonazole |
Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity. |
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DC44909 |
6-Chloro-7-deazapurine-β-D-riboside |
Chloro-7-deazapurine-β-D-riboside is a nucleoside derivative and has antifungal activity. |
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DC45367 |
Latrunculin B |
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity. |
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DC45408 |
Nudicaucin B |
Nudicaucin B is a triterpenoid saponi found in Hedyotis nudicaulis. Nudicaucin B has antifungal activities. |
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DC45431 |
3-Oxobetulin |
3-Oxobetulin, an antifungal agent, shows antifungal activities against white rot fungus L. betulina and the brown rot fungus L. sulphureus. |
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DC45518 |
Tetradehydropodophyllotoxin |
Tetradehydropodophyllotoxin possesses antifungal activity. |
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DC45536 |
Fumitremorgin B |
Fumitremorgin B is a tremorgenic mycotoxin. Fumitremorgin B exhibits significant antifungal activities, with MICs of 6.25-50 μg/mL. |
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DC45537 |
FR179642
Featured
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FR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin. FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379. |
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DC45900 |
Polygodial |
Polygodial (Poligodial) is an antifungal potentiator. Polygodial is a sesquiterpene with anti-hyperalgesic properties. |
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DC45951 |
Isobellidifolin |
Isobellidifolin, a xanthone, is a free radical scavenger and antioxidant compound. Isobellidifolin has potent antifungal effect. |
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DC45967 |
Protoneogracillin |
Protoneogracillin, a furostanol glycoside, shows anti-fungal activity against the plant pathogenic fungus P.oryzae (MMDC=94.0 μM) and cytotoxic activity on K562 cancer cells (IC50=6.6 μM). |
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DC46103 |
Valtrate hydrine B4 |
Valtrate hydrine B4 is a natural compound with antifungal activities. |
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DC46115 |
Colutehydroquinone |
Colutehydroquinone is an isoflavonoid that can be found in the root bark of Colutea arborescens. Colutehydroquinone exhibits antifungal activity. |
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DC46180 |
Aureobasidin A(Basifungin)
Featured
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Aureobasidin A (Basifungin), a cyclic depsipetide, is an antifungal antibiotic. Aureobasidin A (Basifungin) A is an inhibitor of the inositolphosphorylceramide synthase AUR1. |
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