| DC40773 |
Penconazole |
Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats. |
|
| DC40898 |
Triclopyricarb |
Triclopyricarb (SYP-7017) is a strobilurin fungicide that can be used in crops disease control. Triclopyricarb inhibits mycelial growth with EC50 values ranged from 0.006 μg/mL to 0.047 μg/mL. |
|
| DC40916 |
Diethofencarb |
Diethofencarb is a fungicide with strong activity against Botrytis cinerea and Benzimidazole-resistant strains of Botryis spp. Diethofencarb has a role as an antifungal agrochemical. |
|
| DC40926 |
Fosetyl-aluminum |
Fosetyl-aluminum (Fosetyl-Al) is an active ingredient in many fungicides against downy mildew. Fosetyl-aluminum is used to control many diseases caused by Phytophthora spp. on agricultural and horticultural crops. |
|
| DC40954 |
Polyoxin D |
Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, is a potent chitin synthetase inhibitor. |
|
| DC41060 |
(Z)-Lanoconazole |
(Z)-Lanoconazole is the Z configuration of Lanoconazole. Lanoconazole is a potent and orally active imidazole antifungal agent, shows a broad spectrum of activity against fungi?in vitro?and?in vivo. Lanoconazole interferes with ergosterol biosynthesis by inhibiting sterol 14-alpha demethylase and blocking fungal membrane ergosterol biosynthesis. Lanoconazole can be used for the investigation of dermatophytosis and onychomycosis. |
|
| DC41126 |
Nikkomycin Z |
Nikkomycin Z, a nucleoside-peptide, is a selective competitive chitin synthesis inhibitor. Nikkomycin Z has antifungal effects and acts as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine. |
|
| DC41202 |
Metalaxyl-M |
Metalaxyl-M ((R)-Metalaxyl) is the active (R)-enantiomer of Metalaxyl. Metalaxyl-M is a broad-spectrum fungicide that inhibits protein and ribosomal RNA synthesis in?fungi. Metalaxyl is used for research of plant diseases caused by pathogens of the Oomycota division. |
|
| DC41203 |
Dimethomorph |
Dimethomorph is a morpholine fungicide that inhibits fungal cell wall formation. Dimethomorph inhibits mycelial growth of the oomycete fungi P. citrophthora, P. parasitica, P. capsici, and P. infestans (EC50s=0.14 μg/mL, 0.38 μg/mL, <0.1 μg/mL, and 0.16-0.3 μg/mL, respectively) but is less active against the green algae species C. vulgaris or S. obliquus in vitro (EC50s=47.46 μg/mL and 44.87 μg/mL, respectively). Dimethomorph inhibits androgen receptor (AR) activity in a reporter assay in MDA-kb2 human breast cancer cells but not in a yeast antiandrogen screen (IC20s=0.263 μM and 38.5 μM, respectively). |
|
| DC41204 |
Paclobutrazol |
Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins. Paclobutrazol also has antifungal activities. Paclobutrazol, transported acropetally in plants, can also suppress the synthesis of abscisic acid and induce chilling tolerance in plants.Paclobutrazol is typically used to support research on the role of gibberellins in plant biology. |
|
| DC41205 |
Validamycin A |
Validamycin A is an aminoglycoside agricultural antibiotic. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL. Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM. |
|
| DC41245 |
Isoprothiolane |
Isoprothiolane is a systemic fungicide. Isoprothiolane is a rice blast controlling agent against the fungal disease of rice planty?Pyvioutavia oryzae?Cav. |
|
| DC41254 |
Famoxadone |
Famoxadone (DPX-JE874) is a fungicide acting against a broad spectrum of fungi and is widely used in Integrated Pest Management strategies in different agricultural crops. |
|
| DC41256 |
Propamocarb |
Propamocarb is a systemic fungicide. Propamocarb is widely used to protect cucumbers, tomatoes and other plants from pathogens. |
|
| DC41263 |
Cymoxanil |
Cymoxanil is a fungicidal against plant diseases caused by fungi belonging to the Perenosporales. |
|
| DC41335 |
(E)-Coniferin |
(E)-Coniferin is the isomer of Coniferin. Coniferin is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization. |
|
| DC41337 |
Corydalmine |
Corydalmine (L-Corydalmine), an alkaloid isolated from roots of Corydalis Chaerophylla, inhibits spore germination of some plant pathogenic as well as saprophytic fungi. Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity. Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway. |
|
| DC41360 |
Cauloside A |
Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity. |
|
| DC41361 |
Deoxylapachol |
Deoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia. Deoxylapachol has antifungal and anti-cancer activity. |
|
| DC41376 |
Cyclosporin C |
Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs=0.1-5 μg/ml). |
|
| DC41384 |
Pyraclostrobin |
Pyraclostrobin is a strobilurin fungicide that inhibits mitochondrial complex III of fungal and mammalian cells. Pyraclostrobin induces triglyceride accumulation and triglyceride accumulation in 3T3-L1 cells. |
|
| DC41407 |
Fengycin |
Fengycin is a cyclic lipopeptide used as an agricultural fungicide. Fengmycin has an anti-fungal infection effect by damaging the target's cell membrane. |
|
| DC41440 |
Eleutherol |
Eleutherol is a naphthalene isolated from E. americana with antifungal activities. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 μg/mL and 250 μg/mL. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM. |
|
| DC41465 |
Picropodophyllone |
Picropodophyllone, an aryltetralin lignan, is isolated from leaves of Podophyllum hexandrum, and has antifungal activities. |
|
| DC41476 |
L-Diguluronic acid |
L-Diguluronic acid is a linear polysaccharide?copolymer composed of two L-guluronic acid (G) and can be used to from Alginate. Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of antifungal agents delivery carries. |
|
| DC41477 |
L-Triguluronic acid |
L-Triguluronic acid is a linear polysaccharide?copolymer composed of three L-guluronic acid (G) and can be used to from Alginate. Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of anti-fungal agents delivery carries. |
|
| DC41905 |
Bac2A TFA |
Bac2A TFA is an antimicrobial and immunomodulatory peptide. Bac2A TFA is a linear variant of bactenecin and is very effective against fungal pathogens. |
|
| DC41911 |
Iturin A |
IturinA exhibits strong antifungal activity against pathogenic yeast and fungi. Iturin A interacts with the cytoplasmic membrane of the target cell forming ion conducting pores. |
|
| DC42078 |
3,5-Dimethoxybenzoic acid |
3,5-Dimethoxybenzoic acid, isolated from Melia azedarach L. leaves with antifungal activity, is an intermediate in organic synthesis. |
|
| DC42199 |
Diclobutrazol |
Diclobutrazol, a systemic fungicide, is highly active against rusts, powdery mildews, and other fungal phytopathogens. Diclobutrazol can be used as a pesticide to control of various crop diseases. |
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