| DC46280 |
Tolnaftate (D7) |
Tolnaftate D7 (NP-27 D7) is the deuterium labeled Tolnaftate. Tolnaftate (NP-27) is a synthetic thiocarbamate used as an anti-fungal agent. |
|
| DC46361 |
NP213 |
NP213 is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 is effective and well-tolerated in resolving nail fungal infections. |
|
| DC47135 |
Swinholide A |
Swinholide A is the actin-binding marine polyketide and dimerizes actin with the Kd of ~ 50 nM. Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments. Swinholide A disrupts the actin cytoskeleton of cells.Antifungal activity. |
|
| DC47145 |
D75-4590 |
D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity. |
|
| DC47640 |
Fungicide5 |
Fungicide5 is a fungicide candidate targeting succinate dehydrogenase (Ki = 0.095 μM). |
|
| DC47641 |
Benzyl 2-hydroxy-6-methoxybenzoate |
Benzyl 2-hydroxy-6-methoxybenzoate shows the strongest antifungal effect, with IC50 of 25–26 μg/mL for both fungal strains. |
|
| DC47642 |
Antifungal agent 20 |
Antifungal agent 20 exhibits remarkable antifungal activity against Colletotrichum gloeosprioides, Rhizoctonia solani, Phytophthora nicotianae var. nicotianae, Diplodia pinea, Colletotrichum acutatum, and Fusarium oxysporum f. sp. niveum. |
|
| DC47643 |
Phenazine-1-carboxylic acid |
Phenazine-1-carboxylic acid exhibits strong antifungal activity against phytopathogenic fungi. |
|
| DC47644 |
5-epi-Jinkoheremol |
5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin. |
|
| DC47645 |
Antifungal agent 18 |
Antifungal agent 18 is a novel antifungal agent for the treatment of fungal infection. |
|
| DC47646 |
Antifungal agent 15 |
Antifungal agent 15 has the most potent activity with EC50 values of 0.52 and 0.50 μg/mL against S. sclerotiorum and B. cinerea, respectively. |
|
| DC47647 |
Antifungal agent 14 |
Antifungal agent 14 exhibits broad-spectrum activity against the fungal strains with excellent minimum inhibitory concentration values. |
|
| DC47648 |
Nystatin A3 |
Nystatin A3, produced by Streptomyces noursei, a biologically active component of nystatin complex. Antibiotic activity |
|
| DC47649 |
Fungicide4 |
Fungicide4 shows the high activity against the P. infestans strain. |
|
| DC47650 |
Debneyol |
Debneyol exhibits more potent fungicidal activity than validamycin. |
|
| DC47651 |
Antifungal agent 13 |
Antifungal agent 13 exhibits remarkable antifungal activity against Sclerotinia sclerotiorum with an EC50 value of 1.25 mg/L. |
|
| DC47652 |
Antifungal agent 19 |
Antifungal agent 19 shows the potent antifungal activity (EC50 = 0.72 μM). |
|
| DC47653 |
Antifungal agent 17 |
Antifungal agent 17 exhibits excellent antifungal properties against B. cinerea with an EC50 value of 2.86 μg/mL. |
|
| DC47654 |
Antifungal agent 16 |
Antifungal agent 16 displays considerable antibacterial activity and superior antifungal activity with reference to ciprofloxacin and fluconazole, respectively. |
|
| DC47655 |
Antifungal agent 12 |
Antifungal agent 12 is a novel fluconazole-based compound with promising antifungal activities. |
|
| DC47656 |
Antifungal agent 11 |
Antifungal agent 11 shows the promising antifungal activity. |
|
| DC47891 |
T-2307 |
T-2307, an arylamidine, has antifungal activities in vitro and in vivo. T-2307 exhibits broad-spectrum activity against clinically significant pathogens, including Candida species (MIC range, 0.00025 to 0.0078 μg/ml), Cryptococcus neoformans (MIC range, 0.0039 to 0.0625 μg/ml), and Aspergillus species (MIC range, 0.0156 to 4 μg/mL) . |
|
| DC48093 |
Voxvoganan |
Voxvoganan is a potent fungicide that disturbs plasma membrane integrity in a sphingolipid dependent manner. |
|
| DC48094 |
Flutrimazole |
Flutrimazole is an imidazole antifungal with dual anti-inflammatory and antifungal activity. Flutrimazole shows scarce transdermal penetration. Flutrimazole has the advantageous in the research of topical fungal infections with an inflammatory component. |
|
| DC48095 |
Eberconazole |
Eberconazole is a dichlorinated imidazole derivative with antifungal activity. Eberconazole is more active than Clotrimazole, Ketoconazole, and Miconazole. Eberconazole has the potential for the research of dermatophytoses with a topical administration. |
|
| DC48096 |
Ajoene |
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities. |
|
| DC48490 |
N-(2-hydroxy-2-phenylethyl)acetamide |
N-(2-hydroxy-2-phenylethyl)acetamide is isolated from the solid rice cultures of the endophytic fungus Diaporthe eucalyptorum KY-9. N-(2-hydroxy-2-phenylethyl)acetamide exhibits antifungal activities against Alternaria solani. |
|
| DC48520 |
Monaschromone |
Monaschromone, a polyketide metabolite, significantly inhibits the growth of B. cinerea, A. solani, M. oryzae, and G. saubinettii, with the MIC values ranging from 6.25 to 12.5 μM. |
|
| DC48523 |
Buclosamide |
Buclosamide is a topical antimycotic agent. |
|
| DC48528 |
Anserinone B |
Anserinone B is an antifungal and antibacterial benzoquinone. Anserinone B causes radial growth reductions of 50% and 37% against S.fimicola and A. furfuraceus, respectively. Anserinones B also displays moderate cytotoxicity in the NCI’s 60 human tumor cell line panel (GI50=4.4 µg/mL). |
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