| DC48529 |
Canadensolide |
Canadensolide is an antifungal metabolite of Penicillium canadense. |
|
| DC48579 |
Asperfuran |
Asperfuran is an antifungal dihydrobenzofuran derivative produced by a strain of Aspergillus oryzae. Asperfuran weakly inhibits chitin synthase from Coprinus cinereus. Asperfuran shows weak cytotoxicity In HeLa S3 and L1210 cells with an IC50 of 25 μg/ml. |
|
| DC48603 |
Chaetosemin J |
Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM. |
|
| DC48648 |
(E)-β-Farnesene |
(E)-β-Farnesene (trans-β-Farnesene) is a volatile sesquiterpene hydrocarbon which can be found in Phlomis aurea Decne essential oil. (E)-β-Farnesene can be used as a feeding stimulant for the sand fly Lutzomyia longipalpis. |
|
| DC48699 |
Eucalyptacid A |
Eucalyptacid A, an antifungal metabolite, exhibits antifungal activities against Alternaria solani, with MIC values from 6.25 to 50 μM. |
|
| DC48757 |
Isodihydroauroglaucin |
Isodihydroauroglaucin, a fungal metabolite, shows antibacterial activity. |
|
| DC48821 |
(Z)-Fluoxastrobin |
(Z)-Fluoxastrobin is fungicide agent. (Z)-Fluoxastrobin has excellent control of important seed and soilborne pathogens. |
|
| DC48844 |
Dendryphiellin D |
Dendryphiellin D is a compound isolated from fungus Septoria rudbeckiae, a plant pathogenic fungus isolated from the halophyte Karelinia caspia. Dendryphiellin D significantly inhibits the production of nitric oxide (NO). |
|
| DC48920 |
Antibacterial agent 67 |
Antibacterial agent 67 (IC50 = 0.03 μM) has a great enzyme-inhibiting activity increase toward succinate dehydrogenase in comparison with fluxapyroxad (IC50 = 4.40 μM). |
|
| DC48948 |
Berkeleyacetal C |
Berkeleyacetal C, a meroterpenoid compound, shows favorable activity of inhibiting nitrogen oxide (NO) production of macrophages stimulated by lipopolysaccharide (LPS). Berkeleyacetal C exerts anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways. |
|
| DC49092 |
16,17-Dihydroheronamide C |
16,17-Dihydroheronamide C has antifungal activity and is designed as probe for the mode-of-action analysis of heronamide C. |
|
| DC49093 |
ent-Heronamide C |
ent-Heronamide C has antifungal activity and is designed as probe for the mode-of-action analysis of heronamide C. |
|
| DC49142 |
Rhamnolipid RL2 |
Rhamnolipid RL2, is a rhamnolipid, shows antifungal activity. |
|
| DC49191 |
Trichodecenin II |
Trichodecenin II is a fungal metabolite that can be found in conidia of the fungus, Trichoderma viride. |
|
| DC49280 |
32-Desmethylrapamycin |
32-Desmethylrapamycin, a rapamycin derivative is an antifungal agent. 32-Desmethylrapamycin is active Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum. |
|
| DC49354 |
Ticlatone |
Ticlatone is an antifungal that can be used for the research of mycoses. |
|
| DC49358 |
1-Phenylsemicarbazide |
1-Phenylsemicarbazide is an antifungal agent. 1-Phenylsemicarbazide has the potential for preventing mold growth on industrial products. |
|
| DC49463 |
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide |
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor and antifungal agent. |
|
| DC49464 |
Cladospirone bisepoxide |
Cladospirone bisepoxide is a metabolite that isolated from cultures of a fungus. Cladospirone bisepoxide displays selective antibiotic activity against several bacteria and fungi and inhibits germinations of Lepidium sativum at low concentrations. |
|
| DC49465 |
Harzianum A |
Harzianum A is a trichothecene that isolated from the soil-borne fungus Trichoderma harzianum. Harzianum A shows no cytotoxicity against baby hamster kidney cells, no activity against Gram-negative and Gram-positive bacteria, but modest antifungal activity at 100 μg/mL. |
|
| DC49466 |
Viridiol |
Viridiol, a fungal metabolite from Trichodernza viride, shows antifungal activity. |
|
| DC49467 |
CYP51/HDAC-IN-1 |
CYP51/HDAC-IN-1 is a potent, orally active CYP51/HDAC dual inhibitor. CYP51/HDAC-IN-1 inhibits important virulence factors and down-regulated resistance-associated genes. CYP51/HDAC-IN-1 exhibits potent therapeutic effects for both tropical candidiasis and cryptococcal meningitis. |
|
| DC49468 |
FBA-IN-1 |
FBA-IN-1 (compound 2a11) is a first-in-class, covalent and allosteric inhibitor of fructose-1,6-bisphosphate aldolase from Candida albicans (CaFBA). FBA-IN-1 inhibits the growth of Azole-resistant strains 103 with the MIC80 of 1 μg/mL. |
|
| DC49469 |
SDH-IN-1 |
SDH-IN-1 (compound 4i) is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 4.53 μM. SDH-IN-1 has potent antifungal activities. SDH-IN-1 displays potent activity against S. sclerotiorum (EC50 of 0.14 mg/L). |
|
| DC49470 |
BI-10 |
BI-10 is an antifungal compound. BI-10 combined with Fluconazole can inhibit hyphal growth, result in ROS accumulation, and decrease mitochondrial membrane potential (MMP) as well as altering membrane permeability. |
|
| DC49471 |
1233B |
1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94. |
|
| DC49472 |
Bis(methylthio)gliotoxin |
Bis(methylthio)gliotoxin is a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis. |
|
| DC49473 |
Globosuxanthone A |
Globosuxanthone A is a dihydroxanthenone with obvious antifungal activity towards Fusarium graminearum, Fusarium solani, and Botrytis cinerea with MIC values of 4, 8, and 16 μg/mL, respectively. Anticancer activity. |
|
| DC49474 |
Chitin synthase inhibitor 1 |
Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor (IC50=0.12 mM). Chitin synthase inhibitor 1 has potent antifungal activity against drug-resistant fungi variants. |
|
| DC70114 |
1-ECBC |
1-ECBC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.1-ECBC blocked C. albicans biofilm formation in several co-culture models and a rat catheter infection model. |
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