| DC11665 |
PF-00446687 |
PF-00446687(PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
|
| DC8353 |
PF-04418948
Featured
|
PF-04418948 is an orally active, potent, and selective EP2 receptor antagonist (IC50 = 16 nM). |
|
| DC9915 |
PF04995274,PF 04995274
Featured
|
PF-04995274 is a 5-HT4 receptor partial agonist. It thought to act centrally as a pro-cognitive agent that being developed for the treatment of Alzheimer's disease (AD). |
|
| DC11111 |
PF-06764427 |
PF-06764427 (PF06764427) is a potent, selective M1 muscarinic acetylcholine receptor (mAChR) positive allosteric modulator with EC50 of 55 nM, has no measurable agonist or PAM activity at the M2-M5 receptors at 10 uM. |
|
| DC11116 |
PF-06827443 |
PF-06827443 (PF06827443) is a potent, orally bioavailable, and CNS-penetrant M1-selective positive allosteric modulator (PAM) with EC50 of 47 nM, shows no activity against M2-M5 at 10 uM. |
|
| DC7480 |
PF-3274167（cligosiban）
Featured
|
PF-3274167 is a high-affinity nonpeptide oxytocin receptor (OTR) antagonist, with Ki of 9.5 nM. |
|
| DC9752 |
PHCCC
Featured
|
PHCCC is a Group I metabotropic glutamate receptor antagonist (IC50 ~ 3 μM). |
|
| DC9083 |
Pheniramine Maleate |
Pheniramine Maleate ia an antihistamine and vasoconstrictor. |
|
| DC9101 |
Phentolamine mesilate |
Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist. |
|
| DC12183 |
Phenylbiguanide (N-Phenylbiguanide; PBG; 1-Phenylbiguanide) |
Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM. |
|
| DC9318 |
Piboserod
Featured
|
Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist.
|
|
| DC8795 |
Pimavanserin(ACP-103)
Featured
|
Pimavanserin(ACP-103) is a potent and selective 5-HT2A receptor inverse agonist with mean pIC50 of with 8.7 in the cell-based functional assay. |
|
| DC10115 |
Piperoxan hydrochloride
Featured
|
Piperoxan hydrochloride is an α2 adrenoceptor antagonist. |
|
| DC10012 |
Pirmenol hydrochloride
Featured
|
Pirmenol hydrochloride inhibits IK.ACh by blocking muscarinic receptors. The IC50 of Pirmenol for inhibition of Carbachol-induced IK.ACh is 0.1 μM. |
|
| DC9465 |
Pitolisant (hydrochloride)
Featured
|
Pitolisant Hcl(BF2.649;Ciproxidine ) is a novel, potent, and selective nonimidazole inverse agonist at the recombinant human H3 receptor (Ki=0.16 nM).
|
|
| DC5055 |
Plerixafor (AMD3100)
Featured
|
Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. |
|
| DC8741 |
Plerixafor octahydrochloride
Featured
|
Plerixafor octahydrochloride(AMD3100 8HCL) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. |
|
| DC9742 |
Ponesimod
Featured
|
Ponesimod(ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM. |
|
| DC7492 |
SB 258585 hydrochloride |
Potent and selective 5-HT6 receptor antagonist (pKi = 8.6). |
|
| DC7251 |
AM 281
Featured
|
Potent, selective CB1 cannabinoid receptor antagonist/inverse agonist (Ki values are 12 and 4200 nM for CB1 and CB2 receptors respectively). Increases locomotor activity following systemic administration in vivo. Analog of SR141716A (Ki = 14 nM). |
|
| DC8970 |
Pramipexole Base |
Pramipexole is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS). |
|
| DC3151 |
Pramipexole dihydrochloride |
Pramipexole is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM. |
|
| DC8887 |
Pravadoline(WIN 48,098)
Featured
|
Pravadoline is a cannabimimetic aminoalkylindole agonist of the cannabinoid receptors and an inhibitor of Cox-1 and Cox-2, demonstrating powerful analgesic effects through the combination of these actions. |
|
| DC8347 |
PRE-084 hydrochloride
Featured
|
PRE-084 hydrochloride is a high affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). |
|
| DC9805 |
Preladenant(SCH420814)
Featured
|
Preladenant(SCH 420814) is a potent and selective antagonist at the adenosine A2A receptor. |
|
| DC21944 |
PrNMI
Featured
|
PrNMI is a peripherally restricted cannabinoid 1 receptor (CB1R) agonist, significantly alleviates spontaneous pain behaviors in the animals. |
|
| DC10260 |
Prochlorperazine |
Prochlorperazine is a dopamine (D2) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents. It is also a highly potent typical antipsychotic. |
|
| DCAPI1163 |
Prostaglandin E2 (Cervidil)
Featured
|
Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. |
|
| DC4147 |
Prucalopride
Featured
|
Prucalopride is a selective, high affinity 5-HT receptor agonistfor 5-HT4a and 5-HT4b with Ki of 2.5 nM and 8 nM, respectively. |
|
| DC8289 |
Prucalopride succinate |
Prucalopride succinate is a selective, high affinity 5-HT4 receptor agonist with pKi of 8.6/8.1 for 5-HT4a/4b. |
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