| DC9979 |
PRX-08066
Featured
|
PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that causes selective vasodilation of pulmonary arteries. |
|
| DC10290 |
PZM21
Featured
|
PZM21 is a potent and selective μ opioid receptor agonist with an EC50 of 1.8 nM. |
|
| DC11138 |
Guanabenz acetate |
R15A inhibitor. |
|
| DC7828 |
Ramelteon |
Ramelteon is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively. |
|
| DC9322 |
Ramosetron (Hydrochloride)
Featured
|
Ramosetron Hydrochloride(YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.
|
|
| DC9411 |
Reparixin
Featured
|
Reparixin(DF 1681Y) is an inhibitor of CXCL8 receptor, also inhibit CXCR1 and CXCR2 activation, which has been shown to attenuate inflammatory responses in various injury models. |
|
| DC7721 |
RG7090（Basimglurant）
Featured
|
RG7090(CTEP Derivative,Basimglurant, RO4917523) is a negative modulator of metabotropic glutamate receptor subtype 5 (mGluR5; GRM5). |
|
| DC9383 |
Rimonabant (Hydrochloride)
Featured
|
Rimonabant Hcl(SR141716A) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.8 nM.
|
|
| DC8876 |
Rimonabant(SR141716)
Featured
|
Rimonabant(SR141716) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.8 nM. |
|
| DC7268 |
Risperidone(R 64 766) |
Risperidone(R 64 766) is a serotonin 5-HT2 receptor blocker(Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist(Ki= 1.4 nM). |
|
| DCAPI1466 |
Rizatriptan Benzoate |
Rizatriptan Benzoate is a selective serotonin 5-HTID receptor agonist which is structurally derived from tryptamine. |
|
| DC9666 |
Ro 46-2005
Featured
|
Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM. |
|
| DC10583 |
RO 5028442
Featured
|
RO5028442 is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a). |
|
| DC5015 |
Rotigotine Hydrochloride |
Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic α2B receptors. Rotigotine exhibits antiparkinsonian acitivity. |
|
| DCAPI1584 |
Roxatidine Acetate Hydrochloride |
Roxatidine Acetate Hydrochloride is a histamine H2-receptor antagonist used in ulcer treatment. This compound has been found to inhibit platelet function in vitro. |
|
| DC9251 |
RS-102895 hydrochloride
Featured
|
RS 102895 hydrochloride is a chemokine receptor CCR2 antagonist. |
|
| DC12250 |
RS 17053 hydrochloride (RS-17053) |
RS 17053 hydrochloride is a potent and selective α1A adrenoceptor antagonist, with a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays. |
|
| DC8334 |
RS-127445
Featured
|
RS-127445 is a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C receptors. |
|
| DC11039 |
RTI-13951-33
Featured
|
RTI-13951-33 is a potent, selective, brain-penetrant agonist of the orphan receptor GPR88 with EC50 of 25 nM in in vitro cAMP functional assay. |
|
| DCAPI1593 |
Rupatadine
Featured
|
Rupatadine is a dual histamine H1 and PAF antagonist |
|
| DC11271 |
S38093 HCl
Featured
|
S 38093 is a novel brain-penetrant antagonist/inverse agonist of H3 receptors. |
|
| DC10392 |
S1p receptor agonist 1 |
S1p receptor agonist 1 is an S1P receptor agonist extracted from patent WO 2015039587 A1, compound example 2. |
|
| DC7274 |
S1RA
Featured
|
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
|
| DC9264 |
S1RA hydrochloride
Featured
|
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
|
| DC11346 |
Salbutamol (hydrochloride)
Featured
|
Salbutamol is an agonist of the β2-adrenergic receptor (β2-AR; Kd = 759 nM in a radioligand binding assay using CHO cells expressing the human receptor). |
|
| DC8436 |
Salmeterol Xinafoate
Featured
|
Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms. |
|
| DC8610 |
Salmeterol
Featured
|
Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms. |
|
| DC10925 |
SAR-100842
Featured
|
SAR-100842 (SAR100842) is a potent, selective, orally available antagonist of the Lysophosphatidic Acid 1 Receptor (LPA1 receptor) with IC50 of 31 nM in β-arrestin assays. |
|
| DC9313 |
Sarpogrelate (hydrochloride)
Featured
|
Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD.
|
|
| DC7245 |
SB 222200
Featured
|
SB 222200 is a selective, reversible and competitive antagonist of human NK-3 receptor(Ki=4.4 nM) that effectively crosses the blood-brain barrier. |
|
