Cat. No. | Product name | CAS No. |
DC47056 |
Usmarapride
Usmarapride (SUVN-D4010) is a selective 5-HT4 receptor ligand with EC50 value 27.5nM, intended for the symptomatic research of Alzheimer's disease and other disorders of memory and cognition like attention deficient hyperactivity, Parkinson's and schizophrenia. |
1428862-33-2 |
DC47057 |
Vazegepant
Featured
Vazegepant is the first intranasal CGRP receptor antagonist for the study the acute research of migraine. |
1337918-83-8 |
DC47063 |
Enuvaptan
Enuvaptan is a vasopressin receptor antagonist and has the potential for research into renal and cardiovascular diseases. |
2145062-48-0 |
DC47074 |
Sunobinop
Sunobinop (S 117957) is a modulator of the opioid receptor-like orphan receptor (ORL1). |
1126793-40-5 |
DC47080 |
Velufenacin
Velufenacin is a muscarinic receptor antagonist. |
1648737-78-3 |
DC47089 |
Treprostinil palmitil
Treprostinil palmitil (TP) is the prodrug of DP1 and EP2 agonist, Treprostinil (UT-15), whose EC50 values were 0.6 and 6.2 nM, respectively. Treprostinil palmitil is a pure prodrug and possesses no inherent binding to G-protein coupled receptors including prostanoid receptors. |
1706528-83-7 |
DC47092 |
Lazuvapagon
Lazuvapagon is a vasopressin V2 receptor agonist for the research of nocturia. |
2379889-71-9 |
DC47097 |
Navafenterol saccharinate
Navafenterol (AZD-8871) saccharinate is an inhaled, long-acting bronchodilator, which is a muscarinic antagonist and β2 agonist. |
1648550-37-1 |
DC47101 |
γ-Linolenic acid ethyl ester
γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B4 receptor 4 (LTB4) antagonist. |
31450-14-3 |
DC47110 |
Deudomperidone
Domperidone-d4 is a deuterium labeled Domperidone (R33812).Domperidone is a selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine. |
2121525-08-2 |
DC47127 |
Pexopiprant
Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki < 100nM. Pexopiprant can be used in studies of asthma. |
932708-14-0 |
DC47172 |
15-Keto latanoprost
15-Keto latanoprost is a metabolite of Latanoprost, which is an ocular hypotensive agent. |
135646-98-9 |
DC47173 |
Roxindole
Roxindole (EMD 49980), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM). Antipsychotic and antidepressant activities. |
112192-04-8 |
DC47183 |
Aganepag isopropyl
Aganepag isopropyl (AGN-210961) is an EP2 agonist. |
910562-20-8 |
DC47184 |
Rimcazole dihydrochloride
Rimcazole (BW 234U) dihydrochloride is a carbazole derivative that acts in part as a sigma (σ) receptor antagonist. Rimcazole dihydrochloride also binds with moderate affinity to the dopamine transporter and inhibit dopamine uptake. Rimcazole dihydrochloride can attenuate cocaine-induced locomotor activity and sensitization. Rimcazole dihydrochloride also can be used for the research of cancer. |
75859-03-9 |
DC47196 |
UK-432097
UK-432097 is a highly potent and selective A2AAR agonist with a pKi of 8.4 for human A2AAR. UK-432097 has anti-inflammatory and anti-aggregatory properties. UK-432097 has the potential for COPD (Chronic Obstructive Pulmonary Disease) research. |
380221-63-6 |
DC47220 |
Zectivimod
Zectivimod is a sphingosine-1-phosphate receptor agonist. Zectivimod can be used for the research of autoimmune diseases, chronic inflammatory diseases and immunoregulation disorders. |
1623066-63-6 |
DC47235 |
Binodenoson
Binodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging. |
144348-08-3 |
DC47237 |
PD 102807
Featured
PD 102807 is a M4 muscarinic receptor antagonist with an IC50 of 90.7 nM. PD 102807 inhibits M1, M2, M3, M5 muscarinic receptor with IC50s of 6558.7, 3440.7, 950.0, and 7411.7 nM, respectively. Antidyskinetic effect. |
23062-91-1 |
DC47245 |
PSB-0739
PSB-0739 is a high-affinity potent, competitive, nonselective platelet P2Y12 receptor antagonist with a Ki values of 24.9 nM. The P2Y12 receptor plays a crucial role in platelet aggregation. Antithrombotic effect. |
1052087-90-7 |
DC47251 |
FR-171113
FR171113 is a specific and non-peptide thrombin receptor antagonist. FR171113 exhibits the antithrombotic effects of a PAR1 antagonist. FR171113 inhibits thrombin-induced platelet aggregation with an IC50 of 0.29 μM.. |
173904-50-2 |
DC47254 |
BP 897
BP 897 is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist. BP 897 displays a high affinity at the dopamine D3 receptor (Ki=0.92 nM) and a 70 times lower affinity at the D2 receptor (Ki=61 nM). BP 897 exhibits selective inhibition of cocaine-seeking behavior. |
192384-87-5 |