Velpatasvir(GS5816)

  Cat. No.:  DC9751   Featured
Chemical Structure
1377049-84-7
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More than 5000 active chemicals with high quality for research!
Field of application
Velpatasvir(GS-5816) is a potent and selective Hepatitis C virus NS5A inhibitor.
Cas No.: 1377049-84-7
Chemical Name: GS 5816,GS-5816
Synonyms: GS 5816,GS-5816
SMILES: C[C@H]1CC[C@H](N1C(=O)[C@H](C(C)C)NC(=O)OC)C2=NC3=C(N2)C=CC4=CC5=C(C=C43)OCC6=C5C=CC(=C6)C7=CN=C(N7)[C@@H]8C[C@@H](CN8C(=O)[C@@H](C9=CC=CC=C9)NC(=O)OC)COC
Formula: C49H54N8O8
M.Wt: 882.4
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons.target: NS5A
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC9751 Velpatasvir(GS5816) Velpatasvir(GS-5816) is a potent and selective Hepatitis C virus NS5A inhibitor.
DC10104 VX222(Lomibuvir) VCH-222(Lomibuvir) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L.
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DC10728 Pibrentasvir(ABT-530) Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.
DC8183 Paritaprevir(Veruprevir ABT-450) NS3/4A protease inhibitor
DC10818 ABT-493(Glecaprevir) Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM.
DC8238 Danoprevir Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A.
DC7394 Daclatasvir dihydrochloride (BMS-790052) Daclatasvir (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture.
DC5077 Boceprevir(EBP 520; SCH 503034 ) Boceprevir(EBP 520; SCH 503034 ) is useful for Anti HCV.
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