DC9751 |
Velpatasvir(GS5816)
|
Velpatasvir(GS-5816) is a potent and selective Hepatitis C virus NS5A inhibitor. |
DC10104 |
VX222(Lomibuvir)
|
VCH-222(Lomibuvir) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. |
DC8190 |
Ravidasvir hydrochloride (PPI-668)
|
Ravidasvir(PPI-668) is a NS5A Inhibitor. |
DC4121 |
PSI6130
|
PSI-6130(R 1656) is a Hepatitis C Virus Nucleoside Inhibitor. PSI-6130(R 1656) is useful for Antiviral agents. |
DC10728 |
Pibrentasvir(ABT-530)
|
Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6. |
DC8183 |
Paritaprevir(Veruprevir ABT-450)
|
NS3/4A protease inhibitor |
DC10818 |
ABT-493(Glecaprevir)
|
Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM. |
DC8238 |
Danoprevir
|
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. |
DC7394 |
Daclatasvir dihydrochloride (BMS-790052)
|
Daclatasvir (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. |
DC5077 |
Boceprevir(EBP 520; SCH 503034 )
|
Boceprevir(EBP 520; SCH 503034 ) is useful for Anti HCV. |