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Hypertension

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Cat. No. Product Name Field of Application Chemical Structure
DC9666 Ro 46-2005 Featured Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM.
DC7490 Rostafuroxin Featured Rostafuroxin: an ouabain-inhibitor counteracting specific forms of hypertension.
DC4108 Sitaxentan sodium Featured Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and Ki of 1.4 nM and 0.43 nM, respectively.
DCAPI1452 Valsartan Valsartan is a nonpeptide angiotensin II AT1-receptor antagonist with an IC50 ranging from 39.5 to 116 μM. This in turn causes blood vessel dilation.
DC7699 VTP-27999 Featured VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.
DC9113 Ketanserin
DC9178 Ketanserin Tartrate
DC8901 Azilsartan medoxomil Featured Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of  0.62 nM, which used in the treatment of adults with essential hypertension.

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