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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC5559 Xstax-vhll Novel selective β-catenin degrader
DCC5560 Xylariamide A Carbonic anhydrase inhibitor; Fungal metabolite
DCC5561 Xylarianaphthol-1 Novel activator of p21 promoter in a p53-independent manner
DCC5562 Y08624 Novel TRIM24/BRPF1 dual inhibitor with IC 50 values of 0.98 and 1.16 μM, respectively
DCC5563 Y2 Antagonist 36 Novel non-peptidic highly potent, soluble and selective NPY Y2 antagonist
DCC5564 Y2-antagonist-2 Novel, selective, soluble non-​peptidic NPY Y2 receptor antagonist with enhanced CNS exposure
DCC5565 Y-39983 Dihydrochloride Selective Rho-associated kinase (ROCK) inhibitor
DCC5566 Yak037 Tamoxifen-analog that Suppresses Glial L-Glutamate Transport Activity without Interaction with Estrogen_receptor>Estrogen Receptors
DCC5567 Ycw-e11 Novel Inhibitor of Antiapoptotic Bcl-2 Family Proteins
DCC5568 Yh18968 Novel GPR119 Agonist, improving glucose tolerance and augmenting the glucose lowering effect as well as the plasma level of active GLP-1 in normal mice in combination treatment with a dipeptidyl peptidase 4 (DPP-4) inhibitor
DCC5569 Yh-gka Novel glucokinase activator, significantlt decreasing in blood glucose levels with no adverse effects on serum lipids or body weight
DCC5570 Yk-5-252 Novel dual action combretastatin A-4 (CA-4) prodrug, releasing CA-4 through a disulfide bond cleavage mechanism and containing a near-infrared (NIR) fluorophore
DCC5571 Ykl-05-093 Novel salt inducible kinase (SIK) inhibitor, increasing bone formation and bone mass
DCC5572 Ylt192 Novel, Orally Active Bioavailable Inhibitor of VEGFR2 Signaling with Potent Antiangiogenic Activity and Antitumor Efficacy
DCC5573 Ylt205 Novel Inducer of Apoptosis in Human Colorectal Cells via Mitochondrial Apoptosis Pathway, Inhibiting Tumor Growth
DCC5574 Ym-17690 Novel non-analogous leukotriene agonist
DCC5575 ym-201627 Selective growth inhibitor of endothelial cells
DCC5576 Ym-244769 Featured YM-244769 is a potent, selective and orally active Na+/Ca2+ exchanger (NCX) inhibitor. YM-244769 preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode), with IC50s of 18 nM and 50 nM, respectively. YM-244769 efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage. YM-244769 can also increase urine volume and urinary excretion of electrolytes in mice.
DCC5577 ym-298198 Dihydrochloride Potent and selective mGLu1 antagonist
DCC5578 Ym-90k Novel AMPA receptor antagonist
DCC5579 Yml220 Potent and selective microbicidal agent against wild type (wt) HIV-1, NNRTI-, NRTI-, PRI-resistant mutants
DCC5580 Ynt-1310 Water-soluble analog of YNT-707, acting as a potent orexin 1 receptor (OX1R) antagonist
DCC5581 Ynt-707 Novel potent orexin 1 receptor (OX1R) antagonist
DCC5582 Yoyo-1 DNA-intercalating dye as sensitive amyloid probe
DCC5583 Ysy01a Novel Proteasome Inhibitor, Enhancing Cisplatin Cytotoxicity in Cisplatin-Resistant Human Ovarian Cancer Cells, inducing cell cycle arrest on G2 phase in MCF-7 cells via ERα and PI3K/Akt pathways
DCC5584 Yt-146 Selective A 2A receptor agonist
DCC5585 Yu2534342249 Novel γ-lactam pyrazolidinone, targeting penicillin-binding proteins (PBPs) and incorporating a siderophore moiety to facilitate uptake into the periplasm, being effective against multidrug-resistant gram-negative Bacilli
DCC5586 Yw2065 Novel inhibitor of Wnt signaling by stabilizing Axin-1, a scaffolding protein that regulates proteasome degradation of β-catenin
DCC5587 Yycg Inhibitor 16 Novel YycG inhibitor, inhibiting planktonic cells of E. faecalis, including the vancomycin- or linezolid-resistant strains
DCC5588 Yycg Inhibitor 62 Novel YycG inhibitor, significantly inhibited biofilm formation in static and dynamic conditions

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