Cas No.: | 50679-08-8 |
SMILES: | OC(C1CCN(CCCC(c2ccc(C(C)(C)C)cc2)O)CC1)(c1ccccc1)c1ccccc1 |
Formula: | C32H41NO2 |
M.Wt: | 471.67 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Terfenadine is a potent open-channel blocker of hERG with a mean IC50 of 204 nM.Terfenadine normally undergoes extensive first-pass metabolism in the liver to produce an active acidic metabolite. Terfenadine is a widely used, over-the-counter drug to treat allergies. |