DC10280 |
BD1063 dhydrochloride
Featured
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BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist. |
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DC21101 |
BDCRB
Featured
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BDCRB (GW 275175) is a potent and selective inhibitor of human CMV replication by blocking the processing and maturation of viral DNA.. |
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DC10860 |
BDP5290
Featured
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BDP5290 is a potent inhibitor of both ROCK and MRCK with IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively. |
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DC20763 |
BDP8900 |
BDP8900 (BDP-8900) is a highly potent and selective Myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with IC50 of 43 nM (MRCKβ), >100-fold selectivity over related ROCK1 or ROCK2.
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DC20764 |
BDP9066 |
BDP9066 (BDP-9066) is a highly potent and selective Myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with IC50 of 43 nM, >100-fold selectivity over related ROCK1 or ROCK2.
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DC12596 |
BDP-NAC |
BDP-NAC is a novel persulfide donor that shows selectivity towards H2 O2 over other potential oxidative or nucleophilic triggers, resulting in the sustained release of the persulfide of N-acetyl cysteine (NAC). |
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DC20765 |
BDT001
Featured
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BDT001 is a first-in-class, non-competitive FLT3 negative allosteric modulator, effectively prevents extracellular cytokine FL binding to FLT3 with IC50 of 11 uM. |
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DC20319 |
Beauvericin |
Beauvericin is a cyclic hexadepsipeptide with antibiotic and insecticidal effects, shows activity against Gram-positive bacteria and mycobacteria, and is also capable of inducing programmed cell death in mammals.. |
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DC9718 |
BEBT-908(CUDC-908)
Featured
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BEBT-908(CUDC-908)is a novel PI3K/HDAC inhibitor. |
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DC9964 |
BEC hydrochloride
Featured
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BEC is a boronic acid-based arginine analog that acts as a slow-binding, competitive transition state inhibitor of arginase I and II (Ki = 310 nM for human recombinant type II arginase, pH 7.5). |
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DC20668 |
Becampanel |
Becampanel (AMP 397) potent, competitive antagonist of the AMPA receptor (AMPAR) with IC50 of 11 nM. |
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DC9172 |
Beclomethasone Dipropionate |
Beclometasone dipropionate is a potent glucocorticoid agonist; it is a prodrug of the free form, beclometasone. |
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DC8809 |
Bedaquiline fumarate
Featured
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Bedaquiline fumarate(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis. |
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DC21007 |
Befiradol
Featured
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Befiradol (F13640, NLX 112) is a highly potent, selective 5-HT1A receptor agonist with Ki of 2.7 nM. |
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DC12290 |
Befiradol hydrochloride (F 13640 hydrochloride) |
Befiradol hydrochloride is a selective 5-HT1A receptor agonist. |
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DC20030 |
Begacestat (GSI-953) |
Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC50Aβ40=15 nM) for the treatment of Alzheimer's disease. |
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DC7082 |
Belinostat (PXD101)
Featured
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Belinostat (PXD101) is a novel pan-HDAC inhibitor with IC50 of 27 nM, with activity demonstrated in cisplatin-resistant tumors. |
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DC10448 |
Belizatinib(TSR-011)
Featured
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Belizatinib(TSR-011) is an orally available inhibitor of both the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) and the tropomyosin-related kinases (TRK) TRKA, TRKB, and TRKC, with potential antineoplastic activity. |
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DC8160 |
ZGN-440(Beloranib) |
Beloranib is being studied as a first-in-class obesity therapy that demonstrates a unique mechanism of action through methionine aminopeptidase 2 (MetAP2 ) inhibition. |
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DC11470 |
Belotecan hydrochloride(CKD-602)
Featured
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Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic and water-soluble camptothecin derivative. |
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DC12278 |
Belvarafenib
Featured
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Belvarafenib is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively. |
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DC20135 |
Bemesetron (MDL 72222) |
Bemesetron (MDL 72222) is a selective 5-HT3 receptor antagonist with an IC50 of 0.33 nM. Neuroprotective effect. |
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DC9152 |
Benazepril Hydrochloride |
Benazepril hydrochloride, an angiotensin converting enzyme inhibitor, which is a medication used to treat high blood pressure. |
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DC6908 |
Bendamustine HCL (SDX-105, Cytostasane)
Featured
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Bendamustine HCL (Ribomustin, Treanda, SDX-105) is a DNA-damaging agent with IC50 of 50 μM. |
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DC12299 |
Benfluralin |
Benfluralin is a kind of herbicide and an agrochemical which can be used as a pre-emergence herbicide used for the control of grass and other weeds in a range of food and non-food crops. |
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DCAPI1606 |
Benserazide |
Benserazide is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor. |
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DC10701 |
Benzamide (NSC 404988)
Featured
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Benzamide (NSC 404988) is a bioactive compound. |
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DC20185 |
Benzamidine HCl |
Benzamidine is an inhibitor of serine proteases with Ki values of 35, 350, and 220 µM for trypsin, plasmin, and thrombin, respectively. |
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DC26053 |
Benzamil (hydrochloride)
Featured
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Benzamil hydrochloride is a specific and potent sodium channel (ENaC) blocker. |
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DC22184 |
Benzarone |
Benzarone (NSC 82134) is a small molecule inhibitor of Eyes Absen (EYA) protein tyrosine phosphatase activity (IC50=17 uM, EYA3), exhibits selectivity for EYA over PTP1B. |
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