| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC23101 | Chelerythrine chloride Featured | Chelerythrine is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase, or calcium/calmodulin-dependent protein kinase. |
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| DC20266 | Chelerythrine Featured | Chelerythrine is a well-known protein kinase C inhibitor, can inhibit telomerase activity, it also can block the human P2X 7 receptor. |
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| DC20100 | Chelidonic acid Featured | Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blo |
|
| DC12205 | CHEMBL333994 (FK-480) | CHEMBL333994 is a potent and orally effective Cholecystokinin A (CCK-A) antagonist, with an IC50 of 0.67 nM. |
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| DC20338 | Chemocoxib A | Chemocoxib A is a highly potent, selective, cytotoxic COX-2 inhibitor with IC50 of 290 nM and 90 nM for wt mCOX-2 and R120Q COX-2 mutant respectively. |
|
| DC21405 | Chetomin Featured | Chetomin (NSC 289491) is a natural product isolated from Chaetomium species which shows antibacterial and antifungal properties, disrupts the interaction of HIF-1α/p300 at low nanomolar concentrations, strongly increases retinal pigment epithelial cells d |
|
| DC7978 | Tucidinostat(Chidamide) Featured | Chidamide is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM); no inhibition on HDAC4/5/7/9/6(IC50>30 uM). |
|
| DC12515 | Chiglitazar | Chiglitazar (CS-038, CS038) is a potent, dual PPARα/γ dual agonist with EC50 of 1.2, 0.08, 1.7 uM for PPARα, PPARγ and PPARδ, respectively. |
|
| DC9292 | CHIR-090 Featured | CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. |
|
| DC7384 | CHIR-98014 Featured | CHIR-98014 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2. |
|
| DC9703 | CHIR-99021 HCl Featured | CHIR-99021 HCl is a glycogen synthase kinase 3 beta inhibitor that has antiproliferative activity in vitro and in vivo. |
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| DC1023 | CHIR-99021 (CT99021) Featured | CHIR-99021 is a glycogen synthase kinase 3 beta inhibitor that has antiproliferative activity in vitro and in vivo. |
|
| DC12323 | CHK1-IN-2 | CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM |
|
| DC9048 | Chloroambucil | Chlorambucil(WR-139013; CB-1348) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. |
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| DCAPI1255 | Chloramphenicol (Chloromycetin) | Chloramphenicol (Chloromycetin) |
|
| DC12124 | Chlorantraniliprole Featured | Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myobla |
|
| DCAPI1167 | Chlorhexidine HCl | Chlorhexidine hydrochloride is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms. |
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| DCAPI1354 | Chlormezanone (Trancopal) | Chlormezanone (Trancopal) |
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| DC9169 | Chloroquine diphosphate | Chloroquine diphosphate is an antimalarial drug and autophagy/lysosome inhibitor; inhibits Toll-like receptor (TLR) signalling in plasmacytoid dendritic cells (pDCs). |
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| DCAPI1270 | Chlorothiazide | Chlorothiazide |
|
| DC9111 | Chlorpheniramine Maleate | Chlorpheniramine maleate is an histamine H1 receptor antagonist with IC50 of 12 nM. |
|
| DC9082 | Chlorpromazine HCl Featured | Chlorpromazine Hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug. |
|
| DC9062 | Chlorprothixene | Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively. |
|
| DCAPI1339 | Chlorthalidone (Chlortalidone) | Chlortalidone is a diuretic drug used to treat hypertension. |
|
| DC9194 | Chlorzoxazone | Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes.Chlorzoxazone is currently being used as a marker substrate in vitro/vivo studies to qua |
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| DC20623 | CHMFL-ABL-053 | CHMFL-ABL-053 is a potent, selective and orally available Bcr-Abl/Src/p38 kinase inhibitor with IC50 of 70/62/90 nM. |
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| DC10467 | CHMFL-BMX-078 Featured | CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM. |
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| DC20339 | CHMFL-KIT-031 | CHMFL-KIT-031 is a highly selective KIT kinase primary V559D mutant inhibitor with IC50/Kd of 28/266 nM, 10-20 fold selectivity over KIT wt. |
|
| DC20069 | CHMFL-PI3KD-317 | CHMFL-PI3KD-317 is a highly potent, selective and orally active PI3Kδ inhibitor, with an IC50 of 6 nM, and exhibits over 10-1500 fold selectivity over other class I, II and III PIKK family isoforms, such as PI3Kα (IC50, 62.6 nM), PI3Kβ (IC50, 284 nM), PI3 |
|
| DC12199 | Cholestenone | Cholestenone is the intermediate oxidation product of cholesterol. |
|
