| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC20181 | Choline Fenofibrate;ABT-335 | Choline fenofibrate is a newly developed choline salt of fenofibric acid, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist. |
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| DC8116 | Tosedostat (CHR2797) Featured | CHR-2797 is an aminopeptidase inhibitor, with IC50 values of 100 nM for LAP3 (LAP), 150 nM for PSAP (PuSA) and 220 nM for CD13 (Aminopeptidase N). |
|
| DC22173 | CHR-3996 | CHR-3996 (Nanatinostat, VRx-3996, CHR3996, Tractinostat) is a potent, class I-selective, orally active HDAC inhibitor with IC50 of 3-7 nM for HDAC1/2/3. |
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| DC9460 | CHR-6494 Featured | CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. |
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| DC8139 | GMX1778(CHS-828) Featured | CHS-828 is a pyridyl cyanoguanidine anti-tumor agent that has been identified as a competitive inhibitor of Nampt as well as an inhibitor of NF-κB pathway activity. |
|
| DC12329 | ChX710 | ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF) 3. |
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| DC10341 | CHZ868 | CHZ868 is a type II JAK2 inhibitor with an IC50 of 0.17 μM in EPOR JAK2 WT Ba/F3 cell. |
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| DC2088 | CI-1040 (PD184352) Featured | CI-1040 (PD 184352) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM. |
|
| DC20893 | CI-1044 | CI-1044 is a potent, selective and orally bioavailable PDE4 inhibitor with IC50 of 0.27 uM, displays high selectivity for PDE4 versus PDE1/3/5, and no PDE4 subtype (4A-D) selectivities. |
|
| DC21462 | CI-966 | CI-966 (PD 126141) is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively. |
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| DC20894 | CI-966 hydrochloride | CI-966 is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively. |
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| DC21463 | CI-976 Featured | CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM. |
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| DC2060 | CI994 (Tacedinaline) Featured | CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 μM. |
|
| DC12412 | cIAP1 E3 ligase inhibitor D19 | cIAP1 E3 ligase inhibitor D19 (cIAP1 inhibitor D19) is a small-molecule inhibitor of E3 ligase activity of cIAP1, inhibits cIAP1 auto-ubiquitination with IC50 of 14.1 uM, shows no effect on autoubiquitination of BRCA1/BARD1. |
|
| DC12413 | cIAP1 E3 ligase inhibitor D19-14 | cIAP1 E3 ligase inhibitor D19-14 (cIAP1 inhibitor D19-14) is an improved analog of D19, demonstrates significantly increased ability to inhibit cIAP1 autoubiquitination and reduce protein levels of c-MYC in vitro. |
|
| DC9176 | Ciclesonide | Ciclesonide(RPR251526) is a glucocorticoid used to treat obstructive airway diseases. |
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| DCAPI1143 | Ciclopirox (Penlac) | Ciclopirox (Penlac) |
|
| DC12285 | CID 1375606 Featured | CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. |
|
| DC10873 | CID16020046 Featured | CID 16020046 is a potent and selective GPR55(LPI receptor) antagonist; inhibitsGPR55 constitutive activity with IC50 of 0.15 uM. |
|
| DC22056 | CID 9998128 | CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils. |
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| DC12243 | CID-1067700 | CID-1067700 is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM. |
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| DC7253 | CID-2011756 Featured | CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells. |
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| DC8849 | CID-2858522 Featured | CID-2858522 is a selectively inhibits protein kinase C (PKC)-induced activation of the NF-κB pathway (IC50 < 0.1 μM for PMA-stimulated IL-8 production). |
|
| DC20895 | CID3528206 | CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively. |
|
| DC9955 | BCL6 inhibitor(CID5721353) Featured | CID5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor). |
|
| DC7385 | CID-755673 Featured | CID755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM; exhibits selective PKD1 inhibition when compared with AKT, PLK1, CAK, CAMKIIα, and PKC isoforms. |
|
| DC7976 | CID 797718 Featured | CID-797718 is a compound with unknown details. |
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| DC23753 | CID888706 | CID888706 is a small molecule, pan activator of Rho-family GTPases.. |
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| DC20904 | CIDD 0067106 | CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM). |
|
| DCAPI1021 | Cidofovir(Vistide) Featured | Cidofovir(Vistide) |
|
