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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCAPI1113 Clindamycin HCl (Dalacin) Clindamycin HCl (Dalacin)
DCAPI1131 Clindamycin phosphate Clindamycin phosphate
DC10204 Clinofibrate Clinofibrate (S-8527) is a hypelipidemic agent and a HMG-CoA reductase inhibitor.
DC10242 5-Chloro-8-hydroxy-7-iodoquinoline Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.
DC21722 CLK-IN-T3 Featured CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110 nM for CLK1,2 and 3, respectively.
DC11004 CLK2 inhibitor Indazole1 CLK2 inhibitor Indazole1 is a novel potent, selective inhibitor of CLK2 with IC50 of 2.7 nM, 60-fold selectivity over PKA and >600-fold selectivity over a panel of 34 kinases.
DC23464 Clobenpropit Clobenpropit (VUF-9153) is a highly potent histamine H3 antagonist/inverse agonist with pA2 value of 9.93, also displays partial agonist activity at H4 receptors.
DC23440 Clobenpropit dihydrobromide Clobenpropit (VUF-9153) is a highly potent histamine H3 antagonist/inverse agonist with pA2 value of 9.93, also displays partial agonist activity at H4 receptors.
DCAPI1133 Clobetasol propionate Clobetasol propionate
DC12304 Clocapramine hydrochloride hydrate (3-Chlorocarpipramine hydrochloride hydrate) Clocapramine hydrochloride hydrate is an antagonist of the D2 and 5-HT2A receptors.
DCAPI1428 Clofarabine Featured Clofarabine(Clolar; Clofarex) inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase. IC50 Value: 65 nM Target: in vitro: Clofarabine is a second generation purine nucleoside analog with antineoplastic activity. It
DC9156 Clofazimine Clofazimine is a fat-soluble iminophenazine dye, has a marked anti-inflammatory effect, has been used in combination with other antimycobacterial drugs to treat AIDS and Crohn's disease.
DC8681 Clofentezine Clofentezine, a growth inhibitor, has sublethal effects on life-table parameters of Tetranychus urticae Koch females.
DC9183 Clomiphene citrate Clomifene Citrate is a selective estrogen receptor modulator.
DC9081 Clomipramine HCL Clomipramine HCl is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.
DC9021 Clonidine hydrochloride Clonidine Hydrochloride is a centrally acting alpha-agonist hypotensive agent.
DC3147 Clopidogrel hydrogensulfate Clopidogrel (Plavix) is an oral, thienopyridine class antiplatelet agent.
DCAPI1417 Clopidogrel Clopidogrel is an irreversible inhibitor of the P2Y12 receptor, which is responsible for initiating signal transduction via a GPCR. The signal cascade initiates platelet aggregation and thus clopidogrel has the effect of “thinning” the blood.
DCAPI1545 Cloprostenol sodium Cloprostenol Sodium is a synthetic F series prostaglandin that functions as a potent agonist towards the PGF2αR (FP receptor). It is known that Cloprostenol Sodium is less selective than other agonists such as fluprostenol, however it displays more potenc
DC8672 Cloquintocet-mexyl Cloquintocet-mexyl is a herbicide, used to control coarse annual grass of the family poaceae (gramineae).
DC7991 8-​Chloro-​11-​(4-​methyl-​1-​piperazinyl)​-​5H-​dibenzo[b,e]​(1,4)​diazepine N-oxide Featured Clozapine N-oxide is a major metabolite of Clozapine noted to decrease SR-2A (5-HT2 serotonin receptor) density in vitro.
DC9067 Clozapine Clozapine(HF 1854) is a 5-HT2A/2C and dopamine receptor blocker with Ki values of 21, 170, 170, 230 and 330 nM for D4, D3, D1, D2 and D5 receptors respectively.
DC12714 CLP-290 Featured CLP290 (CLP-290) is an orally acirtve small molecule K+-Cl- cotransporter isotype 2 (KCC2) activator, the carbamate prodrug of CLP257; In vivo co-treatment with morphine and oral CLP290 prevented membrane KCC2 downregulation in SDH neurons. Concurrently, co-treatment with CLP290 significantly mitigated MIH and acute administration of CLP257 in established MIH restored normal nociceptive behavior.
DC11061 ClpP inhibitor M21 ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay.
DC9797 18-[4-(2,2-Difluoro-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-8-yl)phenyl]octadecyl-[2-(trimethylazaniumyl)ethoxy]phosphinate Featured CLR1501 is a synthetic analogs of the tumor-targeting agent alkylphosphocholine (APC), which is specifically attracted to cancer cells.
DC11067 CLSP37 CLSP37 (RIPK2 inhibitor CLSP37) is a novel potent, ATP pocket-binding RIPK2 inhibitor with IC50 of 16.3 nM in ADPGlo assay, demonstrates inhibition of both the RIPK2-XIAP interaction, and of cellular and in vivo NOD2 signaling.
DC11068 CLSP43 CLSP43 (RIPK2 inhibitor CLSP43) is a novel potent, ATP pocket-binding RIPK2 inhibitor with IC50 of 19.9 nM in ADPGlo assay, demonstrates inhibition of both the RIPK2-XIAP interaction, and of cellular and in vivo NOD2 signaling.
DC21063 CM03 CM03 is a G-quadruplex-binding compound that potently inhibits cell growth in PDAC cell lines (MIA PaCa-2 IC50=19 nM).
DC10795 CM-272 Featured CM-272 is a first-in-class reversible dual small molecule inhibitor against G9a and DNMTs in hematological malignancies.
DC7605 CM346(Afobazole) Featured CM-346 increased the power of the low-frequency θ-rhythm (4.8–5.8 Hz) and the dominant activity peak (6.0–7.2 Hz) and decreased the spectral power in the 19–20 Hz band.

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