Home > Inhibitors & Agonists
Cat. No. Product name CAS No.
DC23878 20(S)-Hydroxycholesterol

20(S)-Hydroxycholesterol is an allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein, binds at a site distinct from the canonical cyclopamine binding site.

516-72-3
DC9647 20-Deoxyingenol Featured

20-Deoxyingenol is a natural compound.

54706-99-9
DC9655 20-O-Acetylingenol-3-angelate Featured

20-O-Acetylingenol-3-angelate is a diterpene ester that has been found in E. peplus and a derivative of ingenol-3-angelate

82425-35-2
DC23871 22-Azacholesterol

22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells..

3915-24-0
DC10666 MDK-7933 Featured

MDK-7933, also known as HDAC8-IN-1, is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). MDK-7933 was first reported in ChemMedChem. 2012 Oct;7(10):1815-24. MDK-7933 has CAS#1417997-93-3.

1417997-93-3
DCAPI1409 Maxacalcitol

22-Oxacalcitriol is a Vitamin D3 analog which is Non-calcemic as well as a VDR ligand. 22-Oxacalcitriol has been shown to decrease parathyroid hormone (PTH) mRNA expression in vitro. Additionally has been noted to exhibit similar effects to calcitriol in

103909-75-7
DC12367 Cyclic guanosine monophosphate-adenosine monophosphate Featured

2'3'-cGAMP has been used to identify small compounds capable of binding human stimulator of interferon genes (STING). It is also used to study type I interferon response to cytosolic DNA.

1441190-66-4
DC9802 23-hydroxy butulinic acid (23-HBA) Featured

23-hydroxy butulinic acid (23-HBA) is a potent angiogenesis inhibitor.

85999-40-2
DC12231 25-Hydroxycholesterol Featured

25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells.

2140-46-7
DCAPI1508 25-OH-VD2

25-Hydroxyvitamin D2 is used in serum to measure the concentration of vitamin D produced by the skin. It is known that 25-Hydroxyvitamin D2 can be detected in human serum using high-performance liquid chromatography and ultraviolet detection. Vitamin D2,

21343-40-8
DC20210 2-Aminoethanethiol;cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine

2-Aminoethanethiol (cysteamine) is a radiation-protective agent that oxidizes in air to form cystamine.

60-23-1
DC22088 2BAct Featured

2BAct (eIF2B activator 2BAct) is a novel, highly selective, CNS-permeable small molecule eIF2B activator with EC50 of 33 nM in cell-based reporter assays.

2143542-28-1
DC20184 2-cyano-Pyrimidine

2-cyano-Pyrimidine is a cathepsin K inhibitor with an IC50 of 170 nM.

14080-23-0
DC20158 2'-Deoxyadenosine monohydrate Featured

2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.

16373-93-6
DC20144 2-Furoic acid Featured

2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats.

88-14-2
DC20137 2'-Hydroxy-4'-methylacetophenone Featured

2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. It could be used in the preparation of 4’-methyl-2’-[(p-tolylsulfonyl) oxy] acetophenone.

6921-64-8
DC8952 Mesna

2-mercaptoethane sulfonate (Mesna), is a synthetic small molecule, widely used as a systemic protective agent against chemotherapy toxicity, but is primarily used to reduce hemorrhagic cystitis induced by cyclophosphamide.

19767-45-4
DC9044 2-Methoxyestradiol Featured

2-methoxyestradiol (2ME2; NSC-659853) is a natural metabolite of estrogen that is known to inhibit HIF-1 alpha with an IC50 of 0.71 ± 0.11 μM for the inhibition of BPAEC migration.

362-07-2
DC12356 2-NBDG Featured

2-NBDG is a fluorescent indicator for direct glucose uptake measurement and also is an indicator of cell viability.

186689-07-6
DC12293 2''-O-Rhamnosylicariside II

2''-O-Rhamnosylicariside II is a flavonoid glycoside compound and might be beneficial for improving postmenopausal osteoporosis.

135293-13-9
DC8572 2-Phenyl-2-(1-piperidinyl)propane

2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM; IC50 = 5.1 µM).

92321-29-4
DC20134 2-Phenylethanol Featured

2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid that is slightly soluble in water. It has a pleasant floral odor and also an autoantibiotic produced by

60-12-8
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