| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC23934 | FTI-277 Featured | A peptide mimetic of the C-terminal Cys-Val-Ile-Met of K-Ras4B that potently inhibits FTase (Farnesyltransferase) with IC50 of 0.5 nM. |
|
| DC20311 | Apraglutide Featured | A peptidic glucagon like peptide 2 (GLP-2) analogue for treatment of type2 diabetes.. |
|
| DC24173 | Tolfenpyrad | A pesticide agent.. |
|
| DC22952 | (S) 93-31 | A pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM). |
|
| DC24170 | TBHQ | A phenolic antioxidant and a selective inducer and activator of Nrf2 that ameliorates doxorubicin-induced cardiotoxicity in vivo. |
|
| DC22501 | Fosamprenavir calcium | A phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.. |
|
| DC22845 | Disoxaril | A picornavirus replication inhibitor by binding to the hydrophobic pocket within the VP1 coat protein, thus stabilizing the virion and blocking its uncoating.. |
|
| DC22620 | Tiadinil | A plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles. |
|
| DC5895 | Apigenin | A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. |
|
| DC5880 | Piceatannol | A plant metabolite possessing anti-leukemic activity; inhibits the non-receptor kinases, Syk and Lck. |
|
| DC12009 | CPA-7 | A platinum-containing compound that disrupts STAT3 signaling, inhibits cell growth and induces apoptosis in STAT3-activated cancer cells. |
|
| DC22782 | MDL-72527 Featured | A polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase with IC50 of 6.1 and 0.02 uM, respectively. |
|
| DC22387 | Nystatin | A polyene antifungal antibiotic that works by disrupting the cell membrane of the fungal cells.. |
|
| DC22957 | RU-TRAAK-1 | A poorly reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2).. |
|
| DC22647 | NU-7163 | A poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM. |
|
| DC20911 | Omuralide Featured | A potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity).. |
|
| DC21726 | TAK-802 | A potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM. |
|
| DC21727 | TAK-802 hydrochloride | A potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM. |
|
| DC11614 | ENT1-IN-39 | A potent adenosine transport activity of ENT-1 with IC50 of 26.9 nM. |
|
| DC20957 | TCDD | A potent AHR (aryl hydrocarbon receptor) agonist that induces degradation of AhR by the ubiquitin-proteasome pathway. |
|
| DC23997 | Aleglitazar | A potent and balanced dual PPARα/γ agonist (EC50= 50/21 nM). |
|
| DC22969 | BC-54 | A potent and biologically-active PDE4/7 inhibitor with IC50 of 50-100 nM for PDE4A/B/D, and 140 nM for both PDE7A/B. |
|
| DC20804 | BMS-204352 | A potent and effective calcium-sensitive opener of maxi-K potassium channels (maxi-K) with EC50 of 392 nM at -48.4 mV in HEK293 isolated outside-out membrane patches. |
|
| DC22960 | ICA-105574 Featured | A potent and efficacious hERG channel activator steeply potentiates current amplitudes more than 10-fold with EC50 of 0.5 uM. |
|
| DC11715 | PV-1115 | A potent and highly selective Chk2 inhibitor with IC50 of 0.14 nM. |
|
| DC11974 | L 741742 hydrochloride | A potent and highly selective D4 dopamine receptor antagonist with Ki of 3.5 nM, >200-fold selectivity over D2 and D3 receptors. |
|
| DC21158 | JAK3-IN-2 Featured | A potent and highly selective JAK3 inhibitor with IC50 of 0.15 nM. |
|
| DC20835 | BRD-7880 | A potent and highly specific inhibitor of Aurora B and Aurora C with IC50 of 7 and 12 nM respectively, with less activity against Aurora A (IC50>2 uM). |
|
| DC22627 | Trametinib DMSO solvate Featured | A potent and highly specific MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM. |
|
| DC22496 | W-54011 | A potent and orally active non-peptide C5a receptor (CD88. |
|
