| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11698 | α-NETA | A small molecule CMKLR1 antagonist that inhibits chemerin-stimulated β-arrestin2 association with CMKLR1 (EC50=9.7 nM). |
|
| DC22524 | ZSET1446 | A small molecule cognitive enhancer that potentiates acetylcholine-mediated facilitation of inhibitory synaptic transmission in the hippocampal neurons. |
|
| DC9867 | prostaglandin D2（PGD2) inhibitor Featured | A small molecule compound of prostaglandin D2（PGD2) inhibitor. |
|
| DC12003 | Corr4A Featured | A small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.. |
|
| DC20445 | Me6TREN | A small molecule Cu complexing ligand used for atom transfer radical polymerization (ATRP). |
|
| DC21067 | TB-03 | A small molecule Grb2 SH2 domain binding antagonist that synergistically enhances inhibition of K562 leukemia cell proliferation by imatinib (CI=0.774). |
|
| DC22843 | DDX3-IN-16d Featured | A small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3), a human host factor required for the replication of several DNA and RNA viruses. |
|
| DC11645 | Pitstop 2 Featured | A small molecule inhibitor of clathrin terminal domain and inhibits clathrin-mediated endocytosis. |
|
| DC23010 | R-59949(R-59-949) Featured | A small molecule inhibitor of diacylglycerol kinase (DGK) with IC50 of 0.01-10 uM in isolated platelet membranes and in intact platelets. |
|
| DC23017 | R 59022 Featured | A small molecule inhibitor of diacylglycerol kinase (DGK) with IC50 of 2.8 uM, inhibits the phosphorylation of OAG to OAPA with IC50 of 3.8 uM in intact platelets. |
|
| DC24022 | NSC-305787 hydrochloride | A small molecule inhibitor of Ezrin with Kd of 5.85 uM. |
|
| DC23826 | UC-857993 | A small molecule inhibitor of guanine nucleotide exchange factor (GEF) catalytic activity that binds to SOS1 (Kd=14.7 uM) and disrupts GEF-Ras interaction. |
|
| DC23810 | UC-773587 | A small molecule inhibitor of guanine nucleotide exchange factor (GEF) catalytic activity that binds to SOS1 (Kd=3.4 uM) and disrupts GEF-Ras interaction. |
|
| DC11833 | TDP-665759 | A small molecule inhibitor of HDM2-p53 interaction with FP IC50 of 0.7 uM. |
|
| DC25040 | Heclin | A small molecule inhibitor of HECT-type ubiquitin ligase with IC50 of 6.8/6.3/6.9 uM for Smurf2/Nedd4/WWP1, respectively. |
|
| DC22838 | SCH 351125 | A small molecule inhibitor of HIV-1 entry via the CCR5 coreceptor. |
|
| DC11832 | NU-8165 | A small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 16 uM.. |
|
| DC11831 | NU-8231 | A small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 5.3 uM in ELISA assay. |
|
| DC11927 | iNUB | A small molecule inhibitor of NEMO (IKKγ)-ubiquitin binding with EC50 of 9.3 uM, directly binds to NEMO with Kd of 2.14 uM. |
|
| DC25031 | C2-8 | A small molecule inhibitor of polyglutamine (polyQ) aggregation in Huntington's disease neurons. |
|
| DC22761 | NCI-83633 Featured | A small molecule inhibitor of PP2C that activates extensive 3' cleavage at a concentration 50-fold below that required by fluoride or CP.. |
|
| DC22552 | IC-87201 Featured | A small molecule inhibitor of PSD-95/nNOS interaction with IC50 of 31 uM, without inhibiting nNOS catalytic activity. |
|
| DC20360 | DIDS | A small molecule inhibitor of RAD51-mediated homologous recombination. |
|
| DC25034 | Lin28-IN-1632 | A small molecule inhibitor of RNA binding protein Lin28 that blocks the Lin28/let-7 interaction, rescues let-7 processing and function in Lin28-expressing cancer cells. |
|
| DC23774 | MS-444 | A small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 7 nM. |
|
| DC23773 | Okicenone | A small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 90 nM. |
|
| DC22852 | Sortase-IN-6e | A small molecule inhibitor of Staphylococcus aureus sortase with IC50 of 9.3 uM. |
|
| DC22984 | IT-603 Featured | A small molecule inhibitor of the NF-κB family member c-Rel with IC50 of 3 uM in EMSA assays. |
|
| DC22833 | KKL-35 Featured | A small molecule inhibitor of trans-translation that has broad-spectrum antibiotic activity. |
|
| DC21166 | JK-273 | A small molecule inhibitor of α4 integrin-dependent cell migration (IC50=0.5 uM, on the motility of Jurkat T cells) that functions by interacting with γ-parvin. |
|
