Cat. No. | Product name | CAS No. |
DC8041 |
MK-0941
Featured
MK-0941 is a novel Glucokinase activator (GKA) |
1137916-97-2 |
DC7585 |
Omarigliptin
Featured
MK-3102 (MSD) is a novel DPP-4 Inhibitor, which improves glycaemic control with low risk of symptomatic hypoglycaemia. |
1226781-44-7 |
DC5034 |
MK8245
Featured
MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. |
1030612-90-8 |
DC12020 |
MK-8722
Featured
MK-8722 is a systemic, Direct Pan-Activator of AMP-Activated Protein Kinase. |
1394371-71-1 |
DC12255 |
MLN-4760
Featured
MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM). |
305335-31-3 |
DC4136 |
NPS-2143 HCL
NPS 2143 hydrochloride is a selective CaSR (Ca2+-sensing receptor) inhibitor and antagonist, shown to block increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells with an IC50 of 43 nM. NPS 2143 hydrochlori |
324523-20-8 |
DC7214 |
NPS-2143(SB 262470A )
NPS-2143(SB 262470A ) is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively. |
284035-33-2 |
DC10807 |
O304
Featured
O304 is a novel AMPK activator. |
1261289-04-6 |
DC6401 |
Odanacatib (MK 0822)
Featured
Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of human and rabbit cathepsin K with IC50 of 0.2 nM and 1 nM , respectively. |
603139-19-1 |
DC7109 |
Otenabant (CP-945598 free base)
Featured
Otenabant (CP945598) is a recently discovered selective, high affinity, competitive CB1 receptor antagonist with Ki of 0.7 nM. |
686344-29-6 |
DC7227 |
PF-04620110
Featured
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM. |
1109276-89-2 |
DC3108 |
PF-04971729 (Ertugliflozin)
Featured
PF-04971729 is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is currently in phase 2 trials for the treatment of diabetes mellitus. |
1210344-57-2 |
DC10050 |
PF05175157
Featured
PF-05175157 is a potent and selective inhibitor of both acetyl-CoA carboxylase isoform ACC1 located primarily in liver and adipose tissue and isoform ACC2 dominant in skeletal and heart muscle, with IC50 values of 27 nM and 33 nM, respectively. |
1301214-47-0 |
DC11466 |
PF-06409577
Featured
PF-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 isoform with an EC50 of 7 nM. |
1467057-23-3 |
DC9454 |
Ro 28-1675
Ro 28-1675 (Ro 0281675) is a potent allosteric GK activator with a SC1.5 value of 0.24± 0.0019 uM. |
300353-13-3 |
DC9084 |
Rosiglitazone base
Rosiglitazone(BRL-49653) is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ(PPARγ). |
122320-73-4 |
DC8875 |
Saxagliptin
Featured
Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM and Ki of 1.3 nM. |
361442-04-8 |
DC7495 |
SB-334867 HCl
Featured
SB-334867 is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2. |
249889-64-3 |
DC8419 |
SB-334867
Featured
SB-334867 is a selective orexin-1 (OX1) receptor antagonist. |
792173-99-0 |
DC9690 |
Sinogliatin (HMS5552, RO5305552)
Featured
Sinogliatin (HMS5552, RO5305552) is a mall molecule glucokinase (GCK; GK) activator. |
1191996-10-7 |
DCAPI1445 |
strontium ranelate
Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Commonly used as an antiosteoporotic. |
135459-87-9 |
DC10581 |
Succinobucol(AGI 1067)
Featured
Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. |
216167-82-7 |