DC8875 |
Saxagliptin
Featured
|
Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM and Ki of 1.3 nM. |
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DC7495 |
SB-334867 HCl
Featured
|
SB-334867 is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2. |
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DC8419 |
SB-334867
Featured
|
SB-334867 is a selective orexin-1 (OX1) receptor antagonist. |
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DC9690 |
Sinogliatin (HMS5552, RO5305552)
Featured
|
Sinogliatin (HMS5552, RO5305552) is a mall molecule glucokinase (GCK; GK) activator. |
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DCAPI1445 |
strontium ranelate |
Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Commonly used as an antiosteoporotic. |
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DC10581 |
Succinobucol(AGI 1067)
Featured
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Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. |
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DC5073 |
TAK-875(Fasiglifam)
Featured
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TAK-875 is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 0.072 μM. |
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DC4158 |
Tranabant (MK-0364) |
Taranabant is a highly selective cannabinoid-1 (CB1) receptor inverse agonist. |
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DC7515 |
Teglicar
Featured
|
Teglicar, in vitro and in animal models, reduces gluconeogenesis and improves glucose homeostasis, refreshing the interest in selective and reversible L-CPT1 inhibition as a potential antihyperglycemic approach. |
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DC7826 |
Tofogliflozin hydrate |
Tofogliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2). |
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DC8903 |
Troglitazone |
Troglitazone(CS-045), PPARγ agonist, is an anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity. |
|
DC9343 |
ZLN024 (hydrochloride) |
ZLN024 Hcl is a novel AMPK allosteric activator; activated α1β1γ1 and α2β1γ1 by around 2–2.5 fold with an EC50 of about 1–2 uM.
IC50 value: 1-2 uM (EC50) [1]
Target: AMPK activator
ZLN024 activated AMPK in L6 myotubes and stimulated glucose uptake and |
|
DC10320 |
Saroglitazar (Magnesium) |
Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. |
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DC10322 |
Saroglitazar |
Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. |
|
DC7163 |
ZLN005
Featured
|
ZLN005 is a novel transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). |
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DC1076 |
Otenabant(CP945598.HCl)
Featured
|
CP-945598 HCl is a potent and selective cannabinoid type 1 receptor antagonist with Ki of 0.7 nM. |
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