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Metabolic Disorder

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Cat. No. Product Name Field of Application Chemical Structure
DC8875 Saxagliptin Featured Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM and Ki of 1.3 nM.
DC7495 SB-334867 HCl Featured SB-334867 is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2.
DC8419 SB-334867 Featured SB-334867 is a selective orexin-1 (OX1) receptor antagonist.
DC9690 Sinogliatin (HMS5552, RO5305552) Featured Sinogliatin (HMS5552, RO5305552) is a mall molecule glucokinase (GCK; GK) activator.
DCAPI1445 strontium ranelate Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Commonly used as an antiosteoporotic.
DC10581 Succinobucol(AGI 1067) Featured Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects.
DC5073 TAK-875(Fasiglifam) Featured TAK-875 is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 0.072 μM.
DC4158 Tranabant (MK-0364) Taranabant is a highly selective cannabinoid-1 (CB1) receptor inverse agonist.
DC7515 Teglicar Featured Teglicar, in vitro and in animal models, reduces gluconeogenesis and improves glucose homeostasis, refreshing the interest in selective and reversible L-CPT1 inhibition as a potential antihyperglycemic approach.
DC7826 Tofogliflozin hydrate Tofogliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2).
DC8903 Troglitazone Troglitazone(CS-045), PPARγ agonist, is an anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity.
DC9343 ZLN024 (hydrochloride) ZLN024 Hcl is a novel AMPK allosteric activator; activated α1β1γ1 and α2β1γ1 by around 2–2.5 fold with an EC50 of about 1–2 uM. IC50 value: 1-2 uM (EC50) [1] Target: AMPK activator ZLN024 activated AMPK in L6 myotubes and stimulated glucose uptake and
DC10320 Saroglitazar (Magnesium) Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
DC10322 Saroglitazar Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
DC7163 ZLN005 Featured ZLN005 is a novel transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α).
DC1076 Otenabant(CP945598.HCl) Featured CP-945598 HCl is a potent and selective cannabinoid type 1 receptor antagonist with Ki of 0.7 nM.
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