| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC23714 | GDC-0927 R-form | GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer.. |
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| DC23717 | GDC-0927 | GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer.. |
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| DC12062 | GDC-0927 Racemate | GDC-0927 Racemate is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. |
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| DC9592 | GDC-0941 (dimethanesulfonate) | GDC-0941 2 MeSO3H salt is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). |
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| DC7766 | Ravoxertinib Featured | GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1. |
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| DC11504 | GeA-69 Featured | GeA-69(GeA69) is a potent, selective, allosteric, cell-active PARP14 macrodomain 2 (MD2) inhibitor with Kd of 0.86 uM in ITC assays. |
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| DC7806 | Geldanamycin (NSC122750) | Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association. |
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| DC12394 | Gemcabene calcium | Gemcabene (PD-72953, PD72953) is a first-in-class lipid-lowering agent and activator of PARP. |
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| DC12392 | Gemcabene Featured | Gemcabene (PD-72953, PD72953) is a first-in-class lipid-lowering agent and activator of PARP. |
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| DC8487 | Gemcitabine elaidate Featured | Gemcitabine elaidate is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. |
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| DC2107 | Gemcitabine HCl (Gemzar,LY188011) Featured | Gemcitabine Hydrochloride (Gemzar) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively,showed potent activity against COVID-19(SARS-COV-2) with EC50 MERS-COV(1.216), SARS-COV(4.9 |
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| DC2108 | Gemcitabine free base | Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites. |
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| DC3159 | Gemifioxacin Featured | Gemifloxacin mesylate (trade name Factive, Oscient Pharmaceuticals) is an oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. |
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| DC12342 | Gemilukast (ONO-6950) | Gemilukast is an orally active and potent dual cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2) antagonist, with IC50s of 1.7, 25 nM for human CysLT1 and CysLT2, respectively. |
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| DC7131 | GENZ-644282 | Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity(IC50=1.2 nM). |
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| DC10161 | Gepotidacin Featured | Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. |
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| DC12339 | Geraniin | Geraniin is a TNF-α releasing inhibitor with numerous activities including anticancer, anti-inflammatory, and anti-hyperglycemic activities, with an IC50 of 43 μM. |
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| DC20390 | Gerfelin | Gerfelin is an osteoclastogenesis inhibitor (IC50=61 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.15 uM. |
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| DC9606 | Gestodene | Gestodene(SHB 331;WL 70) is a progestogen hormonal contraceptive. |
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| DC10347 | Gestrinone | Gestrinone (R2323) is a synthetic steroid hormone used to treat endometriosis. It inhibits leiomyoma cells with an IC50 of 43.67 μM. |
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| DC21043 | GGTI 2417 Featured | GGTI 2417 is the methyl ester prodrug of GGTI-2418, a highly potent, competitive, and selective inhibitor of GGTase I. |
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| DC21045 | GGTI 2418 sodium | GGTI 2418 sodium (PTX 100) is a highly potent, competitive, and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTI) with IC50 of 9.5 nM, displays 5,600-fold selectivity over FTase. |
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| DC7784 | GGTI-2133 | GGTI-2133 is a potent and selective GGTase I inhibitor |
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| DC21042 | GGTI-2147 Featured | GGTI-2147 is a non-thiol peptidomimetic that inhibits GGTase I and blocks geranyl-geranylation of Rap1A (IC50=0.5 uM). |
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| DC21047 | GGTI-286 dihydrochloride | GGTI-286 is a CAAX peptidomimetic that is a potent, cell-permeable, and selective inhibitor of GGTase I with IC50 of 2 uM, 25-fold more potent than FTI-277. |
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| DC21046 | GGTI-286 | GGTI-286 is a CAAX peptidomimetic, potent, cell-permeable, and selective inhibitor of GGTase I with IC50 of 2 uM, 25-fold more potent than FTI-277. |
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| DC7133 | GGTI-DU40 | GGTI-DU40 is highly selective inhibitor for GGTase-I both in vitro and in living cells. Studies indicate GGTI-DU40 blocks prenylation of a number of geranylgeranylated CaaX proteins. Treatment of MDA-MB-231 breast cancer cells with GGTI-DU40 inhibited thr |
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| DC11246 | Ghrelin agonist HM01 Featured | Ghrelin agonist HM01 is a novel potent, orally available ghrelin (GHS-R) agonist with Ki of 1.42 nM (human GHS-R1a), induces potent activation of intracellular calcium signaling with EC50 of 1.25 nM. |
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| DC8873 | GHRP-2 Acetate | GHRP-2 is a synthetic hexapeptide Growth Hormone Releasing Peptide (GHRP), which acts on the hypothalamus and the pituitary gland to release growth hormone with a slight stimulator effect on Prolactin, ACTH and Cortisol levels. |
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| DC23592 | GI-530159 | GI-530159 (ICA-069771) is a novel potent, selective, mechano-sensitive K2P channel (TERK) opener with EC50 of 1 uM for TERK1. |
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