| DC74586 |
Pyrimidine |
Pyrimidine is an endogenous metabolite. It is used to study the photoinduced ion chemistry of the halogenated pyrimidines, a class of prototype radiosensitizing molecules, and is also used to assess pyrimidine/purine asymmetry quantitatively. |
|
| DC74587 |
XST-14 |
XST-14 is a potent, competitive, and highly selective inhibitor of ULK1 and exhibits an IC50 of 26.6 nM in an in vitro ULK1 kinase activity assay, respectively. XST-14 reduces the phosphorylation of the ULK1 downstream substrate and induces autophagy inhibition. It exhibits antitumor effects. |
|
| DC74588 |
FL118 |
FL118(10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin analog, is a potent and orally active inhibitor of Survivin. FL118 also selectively and independently inhibits three additional cancer-associated survival genes Mcl-1, XIAP, and cIAP2 in a p53 status-independent manner. FL118 displays potent antitumor activity and can be used in cancer research. |
|
| DC74589 |
p-Toluic acid |
p-Toluic acid (4-Methylbenzoic acid) is a methylbenzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc. It also exhibits hepatotoxicological potential in humanised-liver mice. |
|
| DC74590 |
Protokylol hydrochloride |
Protokylol hydrochloride(Caytine hydrochloride, JB-251 hydrochloride) is a salt form of protokylol and is an agonist of β-adrenergic receptor. Protokylol hydrochloride is also used as a bronchodilator. |
|
| DC74591 |
Coenzyme Q1 |
Coenzyme Q1 (CoQ1) is localized to the hydrophobic domain of the phospholipid bilayer of mitochondria, plasma lipoproteins, and other biological membranes. CoQ1 reduction has a strong rotenone-insensitive component and can be used to measure the mitochondrial respiratory chain complex 1 activity. |
|
| DC74592 |
DL-Thiorphan |
Thiorphan (DL-3-Mercapto-2-benzylpropanoylglycine) is a selective NEP (neprilysin) inhibitor with an IC50 of 6.9 nM. It is also a potent inhibitor of enkephalinase, with antinociceptive activity. |
|
| DC74593 |
ACT001(DMAMCL) |
ACT001(DMAMCL, dimethylaminomicheliolide) is a PAI-1 inhibitor and exerts antitumor effects on neuroblastoma (NB) both in vitro and in vivo. It also exerts synergistic effects in combination with cisplatin through the inhibition of the PAI-1/PI3K/AKT pathway. |
|
| DC74594 |
EGTA tetrasodium |
EGTA tetrasodium(Ethylene glycol-bis(β-aminoethyl ether)-N,N,N',N'-tetraacetic acid tetrasodium salt) is a calcium chelator, used for the determination of calcium in the presence of magnesium. EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages. |
|
| DC74595 |
Deutenzalutamide |
Deutenzalutamide (HC-1119, MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. It can be used in a treatment of advanced prostate cancer. |
|
| DC74596 |
Zilurgisertib fumarate |
Zilurgisertib fumarate(INCB-000928 fumarate, NBU-928 fumarate) is a selective ALK 2 inhibitor.It is under development for the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva. |
|
| DC74597 |
3,3-Dimethyl-1-butanol |
3,3-Dimethyl-1-butanol (Neohexanol) is an orally active inhibitor of trimethylamine (TMA) and trimethylamine N-oxide (TMAO). 3,3-dimethyl-1-butanol negatively inhibits the signalling pathways of p65 NF-κB and TGF-β1/Smad3. 3,3-dimethyl-1-butanol has potential applications in cardiovascular disease (CVD). |
|
| DC74598 |
Fasoracetam (NS 105) |
Fasoracetam (NS 105) is a metabotropic glutamate receptor activator with a potential to treat vascular dementia. |
|
| DC74599 |
Ethotoin |
Ethotoin (Peganone) is a hydantoin derivative and an orally active anticonvulsant agent. It also exerts an antiepileptic effect and can be used in epilepsy research. |
|
| DC74600 |
Lotiglipron
Featured
|
Lotiglipron (PF-07081532) is an orally active GLP-1R agonist. It reduces glucose and body weight, and has the potential to be used in Type 2 diabetes mellitus (T2DM) research. |
|
| DC74601 |
Solutol HS-15 |
Solutol HS-15(Polyethylene glycol 12-hydroxystearate) is a Macrogol 15 hydroxy stearate, which improves permeability by disrupting the membrane structure/fluidity change. |
|
| DC74602 |
Potassium clavulanate cellulose |
Potassium clavulanate cellulose (Potassium clavulanate:cellulose (1:1)) is a mixture of potassium clavulanate and cellulose, is a bacterial β-lactamase inhibitor. Potassium clavulanate with the combination of amoxicillin can be used for the research of different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin. |
|
| DC74603 |
2,4-Thiazolidinedione |
2,4-Thiazolidinedione (Thiazolidinedione), an insulin sensitizer, is a specific agonist of peroxisome proliferator-activated receptor (PPAR)γ. Thiazolidinedione treatment corrects impaired muscle insulin action in vivo. |
|
| DC74604 |
Biotin-(L-Thyroxine) |
Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine. L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4). |
|
| DC74605 |
EDI048 |
EDI048 (compound 1.16) is an orally active Cryptosporidium PI4K inhibitor for the research of cryptosporidiosis. |
|
| DC74606 |
Enavermotide |
Enavermotide (UCP2) is an immunological agent for active immunization (antineoplastic). |
|
| DC74607 |
Sucantomotide |
Sucantomotide is an immunological agent for active immunization (antineoplastic). |
|
| DC74608 |
Zelenectide |
Zelenectide (BCY8116) is a Bicycle peptide targeting to Nectin-4, which is a cell adhesion molecule. Zelenectide serves as a Bicycle tumor-targeted immune cell agonist. |
|
| DC74609 |
9-Deazaguanine |
9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP). |
|
| DC74610 |
XY-52 |
XY-52 (Compound 32) is a Stimulation-2 (ST2) inhibitor, with an IC50 value of 5.68 μM in AlphaLISA assay, and 4.59 μM in HEK-Blue assay. XY-52 increases proinflammatory T-cell proliferation. XY-52 reduces the plasma sST2 and IFNγ biomarkers in the graft versus host disease (GVHD) mice model. |
|
| DC74611 |
Civorebrutinib |
Civorebrutinib (WS-413) is a Bruton's tyrosine kinase inhibitor with antineoplastic effect. |
|
| DC74613 |
Tegomil fumarate |
Tegomil fumarate is an immunomodulator. |
|
| DC74614 |
Ucasareotide dasaroxetan |
Ucasareotide dasaroxetan (SarTATE) is diagnostic agent with antineoplastic effect. |
|
| DC74615 |
BC-05 |
BC-05 is an orally active and potent inhibitor of CD13 and proteasome. BC-05 has an IC50 value of 0.13 μM for human CD13 and an IC50 value of 1.39 μM for the 20S proteasome. BC-05 can be used in multiple myeloma research. |
|
| DC74616 |
BTM-3566 |
BTM-3566 is an OMA1 activator. BTM-3566 activates the mitochondrial stress response. BTM-3566 induces apoptosis in diffuse large B-cell lymphomas (DLBCL) cell lines. |
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