| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC20404 | HER2-IN-3 | HER2-IN-3 is a type I HER2 inhibitor that has a similar profile to HER2-IN-2. |
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| DC23730 | Herboxidiene | Herboxidiene (GEX1A, TAN-1609) is a polyketide molecule first isolated from the fermentation broth of Streptomyces chromofuscus, shows in vitro antitumor activity by targeting the SF3B protein in the splicesosome. |
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| DC10967 | HET0016 | HET0016 (HET-0016) is a potent, selective inhibitor of CYP4A, potently inhibits the formation of 20-HETE with IC50 of 8.9 nM in human renal microsomes. |
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| DC12717 | Hetrombopag | Hetrombopag is a potent, selective, orally-active Thrombopoietin (TPO) receptor agonist. |
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| DC12227 | Hexacosanoic acid | Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis. |
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| DC12306 | Hexamethylquercetagetin | Hexamethylquercetagetin is a polymethoxylated flavone in peels of citrus cultivars. |
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| DC8680 | Hexaminolevulinate hydrochloride | Hexaminolevulinate hydrochloride is a fluorescent agent, has approved for cystoscopic detection of papillary bladder cancer. |
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| DC12707 | Hexokinase 2 modulator Comp-1 | Hexokinase 2 modulator Comp-1 is a potent, selective small molecule modulator of Hexokinase 2 (HK2) interaction with the mitochondria, selectively dissociates HK2 from VDAC1 in vitro with IC50 of 92 nM. |
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| DC21904 | HG-12-6 | HG-12-6 is a small-molecule inhibitor that bind preferentially to unphosphorylated IRAK4 with IC50 of 165.1 nM, displays 15-fold selectivity over phosphorylated IRAK4 (IC50=2876 nM). |
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| DC23141 | HG6-64-1 | HG6-64-1 is a potent dual TAK1 and MAP4K2 ((germinal center kinase, GCK)) inhibitor with IC50 of 41 nM and 98 nM, respectively. |
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| DC20405 | HG-7-27-01 | HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases.. |
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| DC21379 | HG-7-92-01(NG25) Featured | HG-7-92-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 292 nM, displays intermediate selectivity profiles (selectivity score=0.18) against 353 kinases.. |
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| DC26060 | gly-arg p-nitroanilide dihydrochloride Featured | H-Gly-Arg-pNA is a colorimetric substrate for thrombin. |
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| DC20406 | HIF2α-IN-2 | HIF2α-IN-2 is a potent, selective, allosteric inhibitor of HIF-2α PAS-B domain with Kd of 81 nM, shows high selectivity and does not affect HIF-1 function. |
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| DC7148 | LY 379268 Featured | Highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors. |
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| DC20083 | H-Ile-Pro-Pro-OH | H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. Antihypertensive tripeptides. |
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| DC23298 | Hinokitiol | Hinokitiol (4-Isopropyltropolone. |
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| DC23710 | Hippuristanol | Hippuristanol is a potent, steroid inhibitor of eukaryotic initiation factor 4A (eIF4A), results in cell cycle arrest at G1 phase, and induces caspases activation and apoptosis. |
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| DC23258 | HIV-1 inhibitor 18A | HIV-1 inhibitor 18A is a novel broad HIV-1 inhibitor that blocks envelope glycoprotein transitions critical for entry, specifically inhibits the entry of a wide range of HIV-1 isolates with mean IC50 of 6.4 uM. |
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| DC9473 | HIV-1 integrase inhibitor | HIV-1 integrase inhibitor ((Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid) is uesful for anti-HIV. |
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| DC23263 | HIV-1 Integrase Inhibitor 7 | HIV-1 Integrase Inhibitor 7 is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 0.58 uM, antiviral activity EC50 of 0.76 uM.. |
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| DC9472 | HIV-1 integrase inhibitor 2 | HIV-1 integrase inhibitor, in the treatment of human immunodeficiency virus (HIV) infection. |
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| DC21116 | HJC0197 Featured | HJC0197 is a potent Epac1 (exchange protein directly activated by cAMP 1) and Epac2 (IC50=5.9 μM for Epac2) antagonist. HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP. |
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| DC21118 | HJC 0726 | HJC 0726 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor, inhibits cAMP-mediated EPAC2 GEF activity with IC50 of 1.0 uM. |
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| DC10626 | HJC0152 | HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor with remarkably improved aqueous solubility. |
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| DC21117 | HJC-0338 | HJC-0338 is a potent and specific EPAC2 antagonist with IC50 of 0.4 uM for competing with 8-NBD-cAMP in binding EPAC2. |
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| DC11366 | HKI 357 | HKI 357 is an irreversible dual inhibitor of the EGF receptor tyrosine kinases EGFR and HER2 (IC50s = 34 and 33 nM, respectively). |
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| DC21119 | HL001 | HL001 (HL 001) is a potent cyclophilin A (CypA) inhibitor with IC50 of 31.6 nM, induces NSCLC cell cycle arrest and apoptosis via restoring p53 expression. |
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| DC21977 | HlyU inhibitor CM14 | HlyU inhibitor CM14 (1025E12) is a specifc, small-molecule inhibitor of transcriptional regulator HlyU activity with EC50 of 30.97 uM, inhibits HlyU from binding to target DNA by covalently modifying Cys30. |
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| DC10414 | HM30181(Encequidar) Featured | HM30181 is a potent and selective inhibitor of P-glycoprotein. |
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