| DC12306 |
Hexamethylquercetagetin |
Hexamethylquercetagetin is a polymethoxylated flavone in peels of citrus cultivars. |
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| DC8680 |
Hexaminolevulinate hydrochloride |
Hexaminolevulinate hydrochloride is a fluorescent agent, has approved for cystoscopic detection of papillary bladder cancer. |
|
| DC12707 |
Hexokinase 2 modulator Comp-1 |
Hexokinase 2 modulator Comp-1 is a potent, selective small molecule modulator of Hexokinase 2 (HK2) interaction with the mitochondria, selectively dissociates HK2 from VDAC1 in vitro with IC50 of 92 nM. |
|
| DC21904 |
HG-12-6 |
HG-12-6 is a small-molecule inhibitor that bind preferentially to unphosphorylated IRAK4 with IC50 of 165.1 nM, displays 15-fold selectivity over phosphorylated IRAK4 (IC50=2876 nM). |
|
| DC23141 |
HG6-64-1 |
HG6-64-1 is a potent dual TAK1 and MAP4K2 ((germinal center kinase, GCK)) inhibitor with IC50 of 41 nM and 98 nM, respectively. |
|
| DC20405 |
HG-7-27-01 |
HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases.. |
|
| DC21379 |
HG-7-92-01(NG25)
Featured
|
HG-7-92-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 292 nM, displays intermediate selectivity profiles (selectivity score=0.18) against 353 kinases.. |
|
| DC26060 |
gly-arg p-nitroanilide dihydrochloride
Featured
|
H-Gly-Arg-pNA is a colorimetric substrate for thrombin. |
|
| DC20406 |
HIF2α-IN-2 |
HIF2α-IN-2 is a potent, selective, allosteric inhibitor of HIF-2α PAS-B domain with Kd of 81 nM, shows high selectivity and does not affect HIF-1 function. |
|
| DC7148 |
LY 379268
Featured
|
Highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors. |
|
| DC20083 |
H-Ile-Pro-Pro-OH
Featured
|
H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. Antihypertensive tripeptides. |
|
| DC23298 |
Hinokitiol |
Hinokitiol (4-Isopropyltropolone. |
|
| DC23710 |
Hippuristanol |
Hippuristanol is a potent, steroid inhibitor of eukaryotic initiation factor 4A (eIF4A), results in cell cycle arrest at G1 phase, and induces caspases activation and apoptosis. |
|
| DC23258 |
HIV-1 inhibitor 18A |
HIV-1 inhibitor 18A is a novel broad HIV-1 inhibitor that blocks envelope glycoprotein transitions critical for entry, specifically inhibits the entry of a wide range of HIV-1 isolates with mean IC50 of 6.4 uM. |
|
| DC9473 |
HIV-1 integrase inhibitor |
HIV-1 integrase inhibitor ((Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid) is uesful for anti-HIV. |
|
| DC23263 |
HIV-1 Integrase Inhibitor 7 |
HIV-1 Integrase Inhibitor 7 is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 0.58 uM, antiviral activity EC50 of 0.76 uM.. |
|
| DC9472 |
HIV-1 integrase inhibitor 2 |
HIV-1 integrase inhibitor, in the treatment of human immunodeficiency virus (HIV) infection. |
|
| DC21116 |
HJC0197
Featured
|
HJC0197 is a potent Epac1 (exchange protein directly activated by cAMP 1) and Epac2 (IC50=5.9 μM for Epac2) antagonist. HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP. |
|
| DC21118 |
HJC 0726 |
HJC 0726 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor, inhibits cAMP-mediated EPAC2 GEF activity with IC50 of 1.0 uM. |
|
| DC10626 |
HJC0152 |
HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor with remarkably improved aqueous solubility. |
|
| DC21117 |
HJC-0338 |
HJC-0338 is a potent and specific EPAC2 antagonist with IC50 of 0.4 uM for competing with 8-NBD-cAMP in binding EPAC2. |
|
| DC11366 |
HKI 357 |
HKI 357 is an irreversible dual inhibitor of the EGF receptor tyrosine kinases EGFR and HER2 (IC50s = 34 and 33 nM, respectively). |
|
| DC21119 |
HL001 |
HL001 (HL 001) is a potent cyclophilin A (CypA) inhibitor with IC50 of 31.6 nM, induces NSCLC cell cycle arrest and apoptosis via restoring p53 expression. |
|
| DC21977 |
HlyU inhibitor CM14 |
HlyU inhibitor CM14 (1025E12) is a specifc, small-molecule inhibitor of transcriptional regulator HlyU activity with EC50 of 30.97 uM, inhibits HlyU from binding to target DNA by covalently modifying Cys30. |
|
| DC10414 |
HM30181(Encequidar)
Featured
|
HM30181 is a potent and selective inhibitor of P-glycoprotein. |
|
| DC12074 |
HM30181 mesylate
Featured
|
HM30181 mesylate is a competitive and potent P-glycoprotein inhibitor. |
|
| DC8768 |
HMN-214
Featured
|
HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM. |
|
| DC20407 |
HMPC |
HMPC is a novel bacteriostatic agent that shows bacteriostatic activity against S. aureus (MIC=4 μg/ml) and rescues Caenorhabditis elegans from S. aureus infection. |
|
| DC22107 |
HMS-101 |
HMS-101 (HMS101) is a potent, selective mutant IDH1 inhibitor, the IC50 is significantly lower in mouse bone marrow cells transduced with IDH1mut compared with IDH1wt (1 uM vs 12 uM, respectively). |
|
| DC9415 |
Hoechst 33342 (trihydrochloride) |
Hoechst 33342 3Hcl(HOE 33342 3Hcl) is an AT-specific DNA minor groove ligand used fluorochrome for visualizing cellular DNA. |
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