| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC12074 | HM30181 mesylate Featured | HM30181 mesylate is a competitive and potent P-glycoprotein inhibitor. |
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| DC8768 | HMN-214 Featured | HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM. |
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| DC20407 | HMPC | HMPC is a novel bacteriostatic agent that shows bacteriostatic activity against S. aureus (MIC=4 μg/ml) and rescues Caenorhabditis elegans from S. aureus infection. |
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| DC22107 | HMS-101 | HMS-101 (HMS101) is a potent, selective mutant IDH1 inhibitor, the IC50 is significantly lower in mouse bone marrow cells transduced with IDH1mut compared with IDH1wt (1 uM vs 12 uM, respectively). |
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| DC9415 | Hoechst 33342 (trihydrochloride) | Hoechst 33342 3Hcl(HOE 33342 3Hcl) is an AT-specific DNA minor groove ligand used fluorochrome for visualizing cellular DNA. |
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| DC9418 | Hoechst 33258 analog | Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA. |
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| DC22129 | HOIPIN-1(JTP-0819958;HOIP inhibitor-1) Featured | HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the N |
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| DC22108 | HOIPIN-8 Featured | HOIPIN-8 (HOIP inhibitor-8) is a potent chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=11 nM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pa |
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| DC10177 | Homoplantaginin | Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia with antiinfammatory and antioxidant properties. |
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| DC12154 | Hosenkoside A | Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina. |
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| DC12148 | Hosenkoside B | Hosenkoside B is a baccharane glycoside isolated from the seeds of impatiens balsamina. |
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| DC12152 | Hosenkoside F ((+)-Hosenkoside F) | Hosenkoside F is a baccharane glycoside isolated from the seeds of impatiens balsamina. |
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| DC12153 | Hosenkoside K | Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina. |
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| DC12149 | Hosenkoside M ((+)-Hosenkoside M) | Hosenkoside M is a baccharane glycoside isolated from the seeds of impatiens balsamina. |
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| DC23978 | hPGDS-IN-1 Featured | hPGDS-IN-1 is a potent, selective hPGDS inhibitor with IC50 of 12 nM in FP or EIA assays.. |
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| DC23894 | HPI-1 Featured | HPI-1 is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Shh (IC50=1.5 uM) without significantly affecting Wnt signaling (IC50>30 uM). |
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| DC12259 | HS-10296 hydrochloride | HS-10296 hydrochloride is an orally available and third-Generation inhibitor of epidermal growth factor receptor (EGFR)-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR. |
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| DC11128 | HS148 Featured | HS148 (DAPK3 inhibitor HS148) is a selective DAPK3 inhibitor with Ki of 119 nM, >10-fold selectivity over Pim kinases.. |
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| DC12616 | HS-152 | HS-152 (HS152) is a specific small-molecule inhibitor of SMAD ubiquitin regulatory factor 1 (SMURF1), not only potently inhibits SMURF1-mediated RHOB degradation with IC50 of 3.2 uM, but also strongly blocks SMURF1-mediated RHOA and SMAD1 degradation (IC5 |
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| DC7426 | HS-173 Featured | HS-173 is a potent PI3Kα inhibitor with IC50 of 0.8 nM. |
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| DC12632 | HS220 Featured | HS220 (HS-220) is a Plasmodium-selective takinib analog that targets atypical P. falciparum protein kinase 9 (PfPK9, Kd=4.1 uM) but does not inhibit HsTAK1, decreases K63-linked ubiquitination in P. falciparum; inhibits P. berghei parasite load in HuH7 ce |
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| DC11126 | HS56 | HS56 (Pim-DAPK3 inhibitor HS56) is a potent, dual Pim/DAPK3 inhibitor with Ki of 72 nM (Pim-3) and 315 nM (DAPK3), shows micromolar potency toward Pim-1 and Pim-2 (Ki=1.5 and 17 uM). |
|
| DC23784 | HS-72 | HS-72 is an allosteric, selective, cell-permeable inhibitor of inducible Hsp70 (Hsp70i or Hsp72), shows selectivity for Hsp70i over the closely related Hsc70 as well as the broader purinome. |
|
| DC21126 | HSD 1169 | HSD1169 is a potent, dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations (D835 or F691, Kd=1-5 nM), potently inhibits acute myeloid leukemia cell lines (IC50=5 nM). |
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| DC21125 | HSD992 | HSD992 is a potent, selective CDK2/3 inhibitor with moderate CDK9 inhibition with IC50 of 18 nM, 57 nM and 49 nM for CDK3/cyclin E, CDK2/cyclin A1 and CDK2/cyclin E, respecively. |
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| DC20064 | HSK0935 (HSK-0935; HSK 0935) | HSK0935 is a potent, highly selective and orally available SGLT2 inhibitor with an IC50 of 1.3 nM. Antihyperglycemic activities. |
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| DC12508 | hSMG-1 inhibitor 11e | hSMG-1 inhibitor 11e is a potent, selective hSMG-1 kinase inhibitor with IC50 of <0.05 nM, >900-fold selectivity over mTOR, and no significant activity against CDK1/2.. |
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| DC12451 | hSMG-1 inhibitor 11j | hSMG-1 inhibitor 11j is a potent, selective hSMG-1 kinase inhibitor with IC5 0of 0.11 nM, 455-fold selectivity over mTOR and no activity against CDK1/2. |
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| DC20408 | HSP27 inhibitor J2 | HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells. |
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| DC23794 | HSP70 modulator 115-7c | HSP70 modulator 115-7c is an artificial co-chaperone, enhancer of Hsp70, stimulats the ATPase and protein-folding activities of a prokaryotic Hsp70 (DnaK) and partially compensated for a Hsp40 loss-of-function mutation in yeast. |
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