Cat. No. | Product name | CAS No. |
DC20975 |
DS-2330
DS-2330 is a phosphorous lowering agent for treating hyperphosphatemia in chronic kidney disease.. |
1634680-81-1 |
DC20971 |
DS-2969b
DS-2969b (DS 11960558) is a novel orally active GyrB inhibitor, inhibits the supercoiling activity of C. difficile DNA gyrase with IC50 of 20 ng/mL. |
2092352-48-0 |
DC11726 |
DS-3032b
Featured
DS-3032b is a potent, selective, orally available MDM2-p53 inhibitor with potential antineoplastic activity. |
1398568-47-2 |
DC22082 |
DS-437
Featured
DS-437 is a potent, selective, dual inhibitor of PRMT5 and PRMT7 with IC50 of 6.0 uM for both, DS-437 is inactive against 29 other human protein-, DNA-, and RNA-methyltransferases. |
1674364-87-4 |
DC12411 |
DS-6930
Featured
DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity. |
1242328-82-0 |
DC22083 |
DS-6930b
DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%. |
|
DC11177 |
DS-70
DS-70 (α4 integrin inhibitor DS-70) is a novel potent α/β- peptidomimetic antagonist of α4 integrin, binds to integrin α4β1 with nanomolar affinity. |
|
DC20976 |
DS-7423
Featured
DS-7423 is a novel potent, small-molecule dual inhibitor of PI3K/mTOR with IC50 of 15.6, 1143, 249, 262 and 34.9 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR respectively. |
1222104-37-1 |
DC11233 |
DS-8500a
DS-8500a (DS8500a) is a novel potent, selective, orally available GPR119 agonist with EC50 of 51.5 nM in human GPR119-expressing CHO-K1 cells, displays no significant effect on 66 receptors, channels, or transporters. |
1371591-51-3 |
DC20973 |
DS86760016
DS86760016 is a novel selective bacterial leucyl-tRNA synthetase (LeuRS) inhibitor with IC50 of 0.38 uM (Escherichia coli, LeuRS). |
1853176-89-2 |
DC22081 |
DS88790512 hydrochloride
DS88790512 is a potent, selective, and orally bioavailable blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).. |
|
DC22080 |
DS88790512
DS88790512 is a potent, selective, and orally bioavailable blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).. |
|
DC12193 |
Ds-HAPP
Ds-HAPP is an anthrancenyl and dansyl fluorophore ligand. |
330163-26-3 |
DC12643 |
DSP-0565
DSP-0565 (DSP0565) is a new drug candidate with broad anti-convulsant activity, does not bind to any GABA-A binding sites, may be caused as the result of its GABAergic function via novel target.. |
1226855-28-2 |
DC20977 |
DSP-1053
DSP-1053 is a novel potent serotonin reuptake (SERT) inhibitor with 5-HT1A partial agonistic activity that binds to human serotonin transporter and 5-HT1A receptor with Ki of 1.02 and 5.05 nM, respectively. |
1176326-78-5 |
DC20979 |
DSP-6952 hydrobromide
DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c. |
1184661-33-3 |
DC20980 |
DT204
DT204 (DT-204) is a novel SCFSkp2 inhibitor that reduces Skp2 binding to Cullin-1 and Commd1, synergistically enhances BTZ-induced apoptosis. |
428497-71-6 |
DC20367 |
dTRIM24
Featured
dTRIM24 is a potent TRIM24 bromodomain inhibitor with IC50 of 217.8 nM (TRIM24 ligand displacement). |
2170695-14-2 |
DC12473 |
Dual BRM and BRG1 inhibitor 14
Dual BRM and BRG1 inhibitor 14 is a potent, orally active inhibitor of Brahma Homolog (BRM)/SMARCA2 and Brahma-related gene 1 (BRG1) with IC50 of <5 nM for both. |
|
DC11175 |
Dual DDR1 and DDR2 inhibitor 5n
Dual DDR1 and DDR2 inhibitor 5n is a highly potent, selective, dual Discoidin domain receptor DDR1 and DDR2 inhibitor with Kd of 7.9 and 8.0 nM, IC50 of 9.4 and 20.4 nM, repectively. |
2241813-33-0 |
DC3149 |
Duloxetine hydrochloride
Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). |
136434-34-9 |
DC12054 |
Duocarmycin TM
Duocarmycin TM is an exceptionally potent antitumor antibiotic. |
157922-77-5 |