| DC10358 |
Lys01 trihydrochloride
Featured
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Lys01 trihydrochloride (Lys05) is a novel lysosomal autophagy inhibitor with IC50 values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay. |
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| DC21262 |
LYS228 |
LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml. |
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| DC23382 |
L-α-Hydroxyglutaric acid disodium salt |
L-α-Hydroxyglutaric acid disodium salt (L-2-Hydroxyglutarate. |
|
| DC22728 |
M-110 |
M-110 is a potent, selective inhibitor of PIM kinase family with preference for PIM-3 with IC50 of 0.047, 2.5 and 2.5 uM for PIM3, PIM1 and PIM2, respectively. |
|
| DC21264 |
M4284 |
M4284 (M-4284) is a high-affinity biphenyl mannoside FimH inhibitor with HAI of 16 nM in hemagglutination assay. |
|
| DC21265 |
M-525 |
M-525 is a first-in-class, highly potent, irreversible small-molecule inhibitor of the menin-MLL interaction with binding IC50 of 3.3 nM in FP assays. |
|
| DC21339 |
MAC1 |
MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity. |
|
| DC21266 |
MAC13772 |
MAC13772 is a potent inhibitor of BioA with an IC50 of 250 nM, a novel antibacterial inhibitor that selectively inhibits PABA biosynthesis in M tuberculosis.. |
|
| DC21267 |
MAC168425 |
MAC168425 is a novel antibacterial inhibitor that interferes with glycine metabolism in E coli.. |
|
| DC21268 |
MAC173979 |
MAC173979 is a novel time-dependent inhibitor of p-aminobenzoic acid biosynthesis with IC50 of 30 uM, represents the first PABA biosynthesis inhibitor with activity against Gram-negative bacteria.. |
|
| DC9922 |
Macranthoidin B |
Macranthoidin B is a major bioactive saponin in rat plasma after oral administration of extraction of saponins from Flos Lonicerae. |
|
| DC11215 |
MAI-150 |
MAI-150 is a peptidomimetic inhibitor of APC-Asef interaction, blocks colorectal cancer migration.. |
|
| DC11201 |
MAI-400 |
MAI-400 (MAI400) is a novel peptide inhibitor of APC-Asef interaction with Kd of 12 nM and IC50 of 0.25 uM. |
|
| DC23792 |
MAL3-101 |
MAL3-101 is a Hsc70 modulator that inhibits Hsp70 ATPase activity, exhibits antiproliferative activity in breast cancer cells SK-BR-3 with IC50 of 27 uM. |
|
| DC22143 |
MALAT1-IN-1
Featured
|
MALAT1 inhibitor 5 (Malat1 inhibitor 5) is a selective small molecule targeting of Metastasis-associated lung adenocarcinoma transcript 1 (Malat1/MALAT1 mouse/human), a highly conserved long non-coding RNA; does not affect Neat1 lncRNA levels. |
|
| DC11066 |
MALT1 paracaspase inhibitor 3 |
MALT1 paracaspase inhibitor 3 is a potent, specific, covalent inhibitor of MALT1 paracaspase with Ki of 10 nM, exhibits 10-and 100-fold improved potency in vitro and in vivo compared with Z-VRPR-fmk. |
|
| DC20141 |
Maltitol
Featured
|
Maltitol is a sugar alcohol used as a sugar substitute. It has 75-90% of the sweetness of sucrose (table sugar) and nearly identical properties. Maltitol may also be used as a plasticizer in gelatin capsules, as an emollient, and as a humectant. |
|
| DC12138 |
Maltohexaose (Amylohexaose) |
Maltohexaose is a natural saccharide, and can be produced from amylose, amylopectin and whole starch. |
|
| DC12157 |
Maltopentaose (Maltopentose) |
Maltopentaose is the shortest chain oligosaccharide that can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin. |
|
| DC11315 |
Manidipine(CV-4093) |
Manidipine is a dihydropyridine L- and T-type calcium channel blocker. |
|
| DC23814 |
MAP4K4-IN-17
Featured
|
MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933. |
|
| DC21916 |
MAP4K4-IN-37 |
MAP4K4-IN-37 is a potent, selective, orally active inhibitor of serine-threonine kinase MAP4K4 with IC50 of 0.4 nM. |
|
| DC20442 |
MAP4K4-IN-44 |
MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay, demonstrates favorable in vivo bioavailability in mouse.. |
|
| DC21857 |
Mapracorat |
Mapracorat (ZK 245186) is a potent, selective and non-steroid glucocorticoid receptor (GR) agonist with binding Ki of 1.9 nM. |
|
| DC21269 |
Marbostat-100 |
Marbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM, displays >200-fold selectivity over HDAC1-5, and HDAC7-10. |
|
| DC8909 |
Maribavir
Featured
|
Maribavir(GW257406X; BW1263W94; 1263W94) inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97. |
|
| DC8031 |
Marimastat |
Marimastat is a broad spectrum MMP inhibitor and selective TACE inhibitor |
|
| DC10639 |
Marinopyrrole A (Maritoclax) |
Marinopyrrole A (Maritoclax) is a selective Mcl-1 antagonist. It binds to Mcl-1, but not Bcl-XL, and targets Mcl-1 for proteasomal degradation. Maritoclax disrupts the interaction between Bim and Mcl-1 with an IC50 of 10.1 μM. |
|
| DC20883 |
Maropitant citrate |
Maropitant citrate (Cerenia) is a selective neurokinin 1 receptor (NK1) antagonist for prevention of vomiting due to motion sickness in dogs.. |
|
| DC9519 |
Maropitant |
Maropitant is a neurokinin (NK1) receptor antagonist. |
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