An non-competitive, allosteric inhibitor of PTP1B with Ki of 0.6 uM for PTP1B1-405.

Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1.

An oral glucocorticoid agonist for the treatment of rheumatoid arthritis..

An orally active adenosine receptor agonist that can induce acute cardiovascular toxicity and coronary vascular injury in vivo..

An orally active anabolic-androgenic steroid and a 19-nortestosterone derivative that has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR..

An orally active pterocarpanquinone that exhibits antitumoral and antileishmanial activity both in vitro and in vivo.

An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo.

An orally active, irreversible inhibitor of protein disulfide isomerase (PDI), forming a covalent bond with the active site cysteines of PDI.

An orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM.

An orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM.

An orally active, second-generation steroid sulfatase inhibitor with IC50 of 0.5 nM.

An orally active, third-generation P-glycoprotein inhibitor that inhibits the drug efflux pump P-glycoprotein, resulting in higher concentrations of antineoplastic agents in tumor cells that are multi-drug resistant due to the overexpression of P-glycopro

An orally available thioxanthone-based DNA intercalator and inhibitor of the DNA repair enzyme apurinic-apyrimidinic endonuclease 1 (APE1) potential antineoplastic activity, also inhibits autophagy.

An orally available, ATP-competitive, small-molecule inhibitor of HSP90 with Ki of 6 nM.

An orally available, brain penetrant p75NTR ligand that blocks p75-mediated cell death, also increases proliferation and survival of hippocampal neural progenitors.

An orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor for the treatment of constipation..

An orally available, small molecule dual VEGFR/PDGFR kinase inhibitor with antiangiogenic and antineoplastic activities.

An orally-active, CNS permeable benzoxaborole antiprotozoal agent.

An organophosphate insecticide agent..

An organophosphorus anthelmintic used against nematodes of the abomasum and small intestine in ruminants. .

An oxazolidinone antibiotic that possesses potent antimicrobial activity in vitro and in vivo..

An α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN.