CAY10595

Cas No.:	916047-16-0
SMILES:	ClC1=CC=C(C2=C1)N(C(C32CC(N(C3=O)CC4=C(C=CC(Cl)=C4)F)=O)=O)CC(O)=O
Formula:	C₂₀H₁₃Cl₂FN₂O₅
M.Wt:	451.23
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

In Vitro CAY10595 (compound 71) is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a Ki of 10 nM. In Vivo Administration of the DP2 antagonist CAY10595 slightly delays the development of CIA. Treatment with CAY10595 reduces IgG2a anti-CII levels without modification of IgG anti-CII levels.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC42503	Taprenepag isopropyl	Taprenepag isopropyl is a highly selective EP2 receptor agonist.
DC47374	Aligeron	Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
DC47373	CAY10580	CAY10580 is a potent and selective prostaglandin EP4 receptor agonist (Ki=35 nM).
DC47183	Aganepag isopropyl	Aganepag isopropyl (AGN-210961) is an EP2 agonist.
DC47172	15-Keto latanoprost	15-Keto latanoprost is a metabolite of Latanoprost, which is an ocular hypotensive agent.
DC47127	Pexopiprant	Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki ＜ 100nM. Pexopiprant can be used in studies of asthma.
DC47089	Treprostinil palmitil	Treprostinil palmitil (TP) is the prodrug of DP1 and EP2 agonist, Treprostinil (UT-15), whose EC50 values were 0.6 and 6.2 nM, respectively. Treprostinil palmitil is a pure prodrug and possesses no inherent binding to G-protein coupled receptors including prostanoid receptors.
DC46853	BGC-20-1531 free base	BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP4 receptor antagonist, with a pKb of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache.
DC46564	Bimatoprost D5	Bimatoprost D5 (AGN 192024 D5) is a deuterium labeled Bimatoprost. Bimatoprost is a prostaglandin analog and is a topical hypotensive agent frequently used for treating ocular hypertension and glaucoma. Bimatoprost also has an antiadipogenic effect.
DC45799	TCS 2510	TCS 2510 is a selective EP4 agonist. TCS 2510 can be used for the research of metabolic diseases.