| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC23138 | CDK-I73 Featured | CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM, shows cytotoxicity against a broad CLL samples with mean LD50 of 80 nM. |
|
| DC9390 | CDK-IN-2 Featured | CDK-IN-2 is a potent and sepecific CDK inhibitor. |
|
| DC10948 | CDN1163 Featured | CDN1163 (CDN-1163) is a small molecule, allosteric activator of SERCA2, dose-dependently increases the Vmax of SERCA2 Ca2+-ATPase activity in ER microsomes; increases Ca2+-ATPase activity and significantly enhances Ca2+ uptake into the ER, attenuates H2O2-stimulated cell death in HEK cells; improves glucose homeostasis and metabolic parameters, increases glucose tolerance in ob/ob mice; CDN1163 reduces lipid accumulation and decreases lipogenesis in obese mice livers. |
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| DC20879 | CDP-840 | CDP-840 (CDP840. |
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| DC20880 | CDP-840 hydrochloride | CDP-840 (CDP840. |
|
| DC23463 | CDPPB Featured | CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively. |
|
| DC22446 | CE-224535 | CE-224535 (PF-04905428) is a potent and selective P2X7 receptor antagonist with IC50 of 1.4 nM (inhibition of the release of lL-1b from monocytes stimulated by ATP). |
|
| DC20881 | CE-245677 | CE-245677 is a potent, selective, orally active, dual Tie2/Trk kinase inhibitor with IC50 of 4.7 nM, 1 nM for Tie2 and TrkA/B, respectively. |
|
| DC20336 | CE3F4 Featured | CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity. |
|
| DC23912 | Cecropin B | Cecropin B is an antimicrobial peptide with MICs(0.5 to 16 ug/ml) against Gramnegative strains. |
|
| DC20987 | Cedazuridine Featured | Cedazuridine (E7727) is a novel cytidine deaminase inhibitor, and a componet of ASTX727 for treatment of hematologic malignancies.. |
|
| DC8686 | Cefetamet pivoxil hydrochloride | Cefetamet pivoxil hydrochloride is an oral third generation cephalosporin antibiotic. |
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| DC9358 | Cefmenoxime (hydrochloride) | Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic. |
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| DC20190 | Cefoxitin | Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. |
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| DC9356 | Cefpiramide (sodium) | Cefpiramide sodium (SM-1652; Wy-44635) is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity. |
|
| DC8687 | Cefpirome sulfate | Cefpirome Sulfate is a fourth generation cephalosporin antibiotic. |
|
| DC9355 | Ceftibuten (dihydrate) | Ceftibuten dihydrate is a third-generation cephalosporin antibiotic. |
|
| DC12245 | Ceftizoxime | Ceftizoxime is a bacterial inhibitor which acts by interfering with bacterial cell wall synthesis and inhibiting cross-linking of the peptidoglycan. |
|
| DC7569 | Z-LEHD-FMK | Cell permeable fluoromethyl ketone (FMK)-derivatized peptides act as effective irreversible Caspase inhibitors with no cytotoxic effects and, therefore, are useful tools for studying Caspase activity. |
|
| DC7568 | Z-DEVD-FMK Featured | Cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo. |
|
| DC23359 | CeMMEC2 | CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.. |
|
| DC10357 | Cenerimod | Cenerimod (ACT-334441) is a potent and orally available sphingosine 1-phosphate 1 receptor (S1P1) agonist extracted from patent WO 2016184939 A1 and WO 2011007324 A1, example 1, with an EC50 of 2.7 nM. |
|
| DC10316 | Cenicriviroc Featured | Cenicriviroc is an orally active, dual CCR2/CCR5 antagonist, and displays potent anti-inflammatory and aninfective activity. |
|
| DC21554 | AS 703569 | Cenisertib (AS 703569;R763) is a novel potent, orally available inhibitor of Aurora kinases, exhibits signifficant anti-proliferative activity against a wide range of tumor cells both in vitro and in vivo (A549 EC50=9 nM). |
|
| DC12318 | Centanafadine hydrochloride (EB-1020 (hydrochloride)) | Centanafadine (hydrochloride) is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively. |
|
| DC12319 | Centanafadine (EB-1020) | Centanafadine is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively. |
|
| DC10010 | Centrinone Featured | Centrinone is a selective and reversible inhibitor of polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole/centrosome assembly. |
|
| DC22796 | CEP-1347 | CEP-1347 (KT-7515) is a potent and selective MLK inhibitor that completely rescues motoneurons and inhibits JNK1 activation with IC50 of 20 nM. |
|
| DC8777 | CEP-32496 hydrochloride | CEP-32496 Hcl is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. |
|
| DC10337 | CEP-40783 Featured | CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. |
|
