| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC9600 | Senicapoc Featured | Senicapoc(ICA17043) is a potent and selective Gardos channel blocker; blocked Ca(2+)-induced rubidium flux from human RBCs/ inhibited RBC dehydration with IC50s of 11 nM/30 nM, respectively. IC50 value: 11/30 nM [1] Target: Gardos channel in vitro: I |
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| DCAPI1485 | Silodosin Featured | Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. Silodosin causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it ca |
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| DC8592 | Sivelestat (sodium salt hydrate) Featured | Sivelestat(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse. |
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| DC8500 | SKQ1(Visomitin) Featured | SKQ1 prevents amyloid-beta-induced impairment of long-term potentiation in rat hippocampal slices. |
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| DC9732 | Sufugolix(TAK-013) Featured | Sufugolix(TAK-013) is a non-peptide, orally-active, selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (IC50 = 0.1 and 0.06 nM for affinity and in vitro inhibition, respectively). |
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| DC11026 | Tecovirimat Featured | Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses; ST-246 is active against multiple orthopoxviruses, including vaccinia, monkeypox, c |
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| DC9148 | Tolvaptan Featured | Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation. |
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| DC11385 | Trofinetide(NNZ2566) Featured | Trofinetide (NNZ-2566) is an analog of a molecule which is derived from IGF-1 and occurs naturally in the brain. IGF-1 is a growth factor stimulated by growth hormone. |
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| DC9816 | Valbenazine（NBI-98854） Featured | Valbenazine(NBI-98854) is a potent and selective VMAT2 inhibitor.. |
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| DC9187 | Mosapride Citrate | Mosapride citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist. |
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