DC22809 |
c-FMS-IN-8
Featured
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c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.. |
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DC12580 |
CG-806
Featured
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CG-806 (CG806, CG'806) is a novel potent, pan-FLT3/BTK multi-kinase inhibitor with impressive inhibition of leukemic cell proliferation with IC50 at sub-nanomolar or low nanomolar levels. |
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DC7101 |
CGK733
Featured
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CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM. |
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DC10722 |
CGP-71683A
Featured
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CGP 71683A is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity. |
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DC23919 |
CGP-42112
Featured
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CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor(AT2 receptor) agonist with Ki of 0.24 nM. |
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DC23830 |
CGP-53353 |
CGP-53353 (DAPH-7) is a selective inhibitor of PKCβII with IC50 of 0.41 uM, shows weak activity on PKCβI with IC50 of 3.8 uM. |
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DC20887 |
CGP-74514A hydrochloride |
CGP-74514A hydrochloride is a potent CDK1 inhibitor with IC50 of 25 nM. |
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DC24112 |
CGS 21680 |
CGS 21680 is a specific adenosine A2A subtype receptor agonist with Ki of 27 nM. |
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DC21331 |
CGS 27023A |
CGS 27023A (MMI 270) is a potent, orally active MMP inhibitor with Ki of 8-43 nM for MMP1/2/3/9. |
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DC7102 |
CH5132799
Featured
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CH5132799 selectively inhibits class I PI3Ks, such as PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ with IC50 values of 0.014, 0.12, 0.50, and 0.36 uM, respectively; shows less inhibition of class II PI3Ks, class III PI3ks, and mTOR. |
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DC22054 |
CH5447240
Featured
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CH5447240 is a novel potent, selective, orally active hPTHR1 agonist with EC20 of 3.0 nM and EC50 of 12 nM. |
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DC12415 |
CH7057288
Featured
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CH7057288 (CH-7057288) is a novel potent and selective pan-TRK inhibitor with IC50 of 1.1/7.8/5.1 nM for TRKA/TRKB/TRKC, respectively. |
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DC20337 |
Chaetocin |
Chaetocin is a potent, specific, SAM-competitive inhibitor of histone H3K9 methyltransferase (HMT) SU(VAR)3-9 with IC50 of 0.6 uM, no actiivty against H4 Lys20-specific HMT PRSET7 and SET7/9. |
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DC5135 |
Chaetominine |
Chaetominine , an alkaloidal metabolite with a new framework, was characterized from the solid-substrate culture of Chaetomium sp. |
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DC12545 |
CHDI-390576
Featured
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CHDI-390576 (CHDI390576) is a potent, cell permeable and CNS penetrant class IIa HDAC inhibitor with IC50 of 54/60/31/50 nM for HDAC4/5/7/9, respectively. |
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DC23101 |
Chelerythrine chloride
Featured
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Chelerythrine is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase, or calcium/calmodulin-dependent protein kinase. |
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DC20266 |
Chelerythrine
Featured
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Chelerythrine is a well-known protein kinase C inhibitor, can inhibit telomerase activity, it also can block the human P2X 7 receptor. |
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DC20100 |
Chelidonic acid
Featured
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Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blo |
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DC12205 |
CHEMBL333994 (FK-480) |
CHEMBL333994 is a potent and orally effective Cholecystokinin A (CCK-A) antagonist, with an IC50 of 0.67 nM. |
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DC20338 |
Chemocoxib A |
Chemocoxib A is a highly potent, selective, cytotoxic COX-2 inhibitor with IC50 of 290 nM and 90 nM for wt mCOX-2 and R120Q COX-2 mutant respectively. |
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DC21405 |
Chetomin
Featured
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Chetomin (NSC 289491) is a natural product isolated from Chaetomium species which shows antibacterial and antifungal properties, disrupts the interaction of HIF-1α/p300 at low nanomolar concentrations, strongly increases retinal pigment epithelial cells d |
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DC12515 |
Chiglitazar |
Chiglitazar (CS-038, CS038) is a potent, dual PPARα/γ dual agonist with EC50 of 1.2, 0.08, 1.7 uM for PPARα, PPARγ and PPARδ, respectively. |
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DC9292 |
CHIR-090
Featured
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CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. |
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DC12323 |
CHK1-IN-2 |
CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM |
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DC9048 |
Chloroambucil |
Chlorambucil(WR-139013; CB-1348) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. |
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DCAPI1255 |
Chloramphenicol (Chloromycetin) |
Chloramphenicol (Chloromycetin) |
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DC12124 |
Chlorantraniliprole
Featured
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Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myobla |
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DCAPI1167 |
Chlorhexidine HCl |
Chlorhexidine hydrochloride is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms. |
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DCAPI1354 |
Chlormezanone (Trancopal) |
Chlormezanone (Trancopal) |
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DCAPI1270 |
Chlorothiazide |
Chlorothiazide |
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