| DC9803 |
CMP8
Featured
|
CMP8 is a high-affinity ligand that binds only to mutant ERLBD. |
|
| DC23508 |
CMPD167 |
CMPD167 (MRK-1) is an orally acitve small molecule that binds to CCR5 to inhibit gp120 association, inhibits different stages of the virus-cell attachment and entry process (CCR5-using virus SHIV-162P3, IC50<1 nM).. |
|
| DC22512 |
CMPDA
Featured
|
CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays. |
|
| DC12476 |
CN427
Featured
|
CN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.. |
|
| DC12477 |
CN750 |
CN750 (CN-750) is novel BRD4 (BD1, 2) inhibitor with IC50 of 44 nM, MV4-11 IC50 of 0.54 uM. |
|
| DC10752 |
CNDAC HCl
Featured
|
CNDAC (DFP-10917; TAS-109) is an orally available deoxycytosine nucleoside analog with potential antineoplastic activity. |
|
| DC9370 |
CNP-AFU |
CNP-AFU (2-Chloro-4-nitrophenyl α-L-fucopyranoside) is a substrate for alpha-L-fucosidase(AFU). |
|
| DC20346 |
CN-SAH |
CN-SAH is a potent and selective inhibitor of histone methyl transferase DOT1L with IC50 of 26 nM, displays >10-fold selectivity over DNMT1, PRMT3, PRMT5, and G9α.. |
|
| DC12103 |
CNT2 inhibitor-1 |
CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2. |
|
| DC23180 |
CNV1014802(Raxatrigine)
Featured
|
CNV1014802 (GSK-1014802, Raxatrigine, Vixotrigine, BIIB074) is a potent, selective Nav1.7 sodium channel blocker, shows analgesic effects and potential in the treatment of cognitive symptoms of schizophrenia in vivo. |
|
| DC7104 |
CNX-1351 |
CNX-1351 is a selective covalent Inhibitor of PI3Kα. CNX-1351 was tested against all four of the class I PI3K enzymes α, β, γ, and δ. |
|
| DC7105 |
CNX-2006
Featured
|
CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR. |
|
| DC7161 |
CNX-774
Featured
|
CNX-774 is a potent, selective, and orally available small molecule inhibitor of Btk (IC50< 1 nM) that forms a ligand-directed covalent bond with Cys-481, a non-conserved amino acid within the active site of the enzyme. |
|
| DC24119 |
Cobimetinib racemate |
Cobimetinib racemate is the racemate form of Cobimetinib (GDC-0973, XL518), which is a potent, highly selective inhibitor of MEK1/2.. |
|
| DC22505 |
Cobimetinib R-enantiomer |
Cobimetinib R-enantiomer (GDC-0973. |
|
| DC8863 |
Coelenterazine
Featured
|
Coelenterazine is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques. |
|
| DC10336 |
Coenzyme Q9
Featured
|
Coenzyme Q9, a nine isoprenyl group-containing member of the ubiquinone family, is a normal constituent of human plasma. |
|
| DC22149 |
COH-SR4 |
COH-SR4 (Mitochondria uncoupler SR4) is a bonafide uncoupler that induces energetic stress on cells, consequently leading to AMPK activation and mTOR inhibition without any effects on ERK/MEK MAPK signaling. |
|
| DC23785 |
Col 003 |
Col 003 is a small-molecule compound that inhibits the interaction of Hsp47 with collagen with IC50 of 1.8 uM, binds to the collagen-binding site on Hsp47. |
|
| DC7813 |
Collagen proline hydroxylase inhibitor |
Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor; useful for antifibroproliferative agents. |
|
| DC7608 |
OXi-4503 |
Combretastatin A1 diphosphate OXi4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. |
|
| DC22270 |
Compound 621433144 |
Compound 621433144 (ZINC000621433144, Z3269026405) is a potent, selective full agonist of the D4 receptor with 2,500-fold subtype selectivity. |
|
| DC22117 |
Compound 7004 |
Compound 7004 (IRAK2 mimetic 7004) is a small molecule mimetic of a-helical domain of IRAK2, inhibit IL-33–induced NF-κB transcriptional activity (IC50=9.7 uM) by disrupting Myddosome formation. |
|
| DC8340 |
myo-Inositol,1,2-anhydro-
Featured
|
Conduritol B Epoxide (CBE) is a specific covalent inhibitor of β-glucosidase which results in the accumulation of glucocerebroside. |
|
| DC21345 |
Contezolid |
Contezolid (MRX I) is an orally active oxazolidinone agent with antibacterial activity Gram-positive pathogens, including MRSA, penicillin-PRSP, PISP, and vancomycin-resistant enterococci (VRE) with MIC of 0.25-4 ug/mL. |
|
| DC10776 |
Cordycepin
Featured
|
Cordycepin is an adenosine analogue, which is readily phosphorylated to its mono-, di-, and triphosphate intracellularly. It has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities. |
|
| DC22488 |
Corticotropin-releasing factor (human)
Featured
|
Corticotropin-releasing hormone (CRH) is a peptide hormone involved in the stress response.. |
|
| DC22479 |
Cortisone acetate |
Cortisone acetate (Cortisone 21-acetate) is a synthetic glucocorticoid corticosteroid and corticosteroid ester. |
|
| DC23908 |
Cortisone
Featured
|
Cortisone is a pregnane (21-carbon) steroid hormone, one of the main hormones released by the adrenal gland in response to stress. |
|
| DC10686 |
Cosan-528
Featured
|
Cosan-528 is a bioactive chemical. |
|
