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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC23729 FR-901464 Featured FR-901464 is a potent antitumor natural product that binds to the splicing factor 3b (SF3b) complex and inhibits pre-mRNA splicing, inhibits cell cycle progression at G1 and G2/M phases..
DC8631 Framycetin sulphate Framycetin sulphate
DC8003 FRAX-486 Featured FRAX486 is a selective inhibitor of group I PAKs with IC50s of 8.25/39.5, /55.3 nM for PAK1/PAK2/PAK3 respectivelt; less potent for PAK4(IC50=779 nM).
DCQ-033 fraxin Fraxin is a coumarin glycoside that has been found in Fraxinus and has anti-inflammatory activity.
DC23050 fraxinellone Featured Fraxinellone is a selective blocker of voltage-dependent Ca2+ channel, which possesses antimicrobial, anti-inflammatory, neuroprotective and vasorelaxing activities.
DC9344 Frentizole Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction.
DC20208 Frovatriptan Succinate Frovatriptan Succinate is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
DC21026 FSC 231 FSC 231 (FSC231) is the first, cell-permeable small-molecule inhibitor of PICK1 PDZ domain with Kd of 10.1 uM.
DC23388 FT-001 FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1.
DC20272 FT113 Featured FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme.
DC22096 FT895 FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM).
DC11029 FTBMT Featured FTBMT is a novel selective GPR52 agonist of GPR52, increases intracellular cAMP levels in CHO cells expressing human, mouse, or rat GPR52, with pEC50 of 7.03, 6.85, and 6.87M, respectively.
DC12537 FtsZ inhibitor C109 FtsZ inhibitor C109 (Compound 10126109) is a broad spectrum antibacterial compound that inhibits the cell division protein FtsZ, inhibits the FtsZ GTPase activity with IC50 of 8.2 uM.
DC12362 Fuchsine base monohydrochloride Fuchsine base (monohydrochloride) is a magenta dye, which is certified for use for acid-fast staining with carbol-fuchsin.
DCAPI1052 Fudosteine Fudosteine
DC11394 Fulacimstat(BAY 1142524) Featured Fulacimstat(BAY 1142524) is a small molecule chymase inhibitor.
DC4200 Fulvestrant Featured Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.094 nM.
DC8855 Fumagillin Featured Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
DCAPI1020 Fumalic acid (Ferulic acid) Featured Fumalic acid (Ferulic acid)
DC21027 Fumosorinone Fumosorinone is a novel potent, selective protein tyrosine phosphatase SHP2 inhibitor with IC50 of 6.31 uM.
DC9069 Furosemide Furosemide (Lasix) is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema.
DC10240 Fusidate Sodium Fusidate Sodium is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
DC21792 FV-100 FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro..
DC21031 FzM1.8 FzM1.8 is a small molecule, allosteric agonist of the Frizzled receptor Fzd4 with pEC50 of 6.4, potentiates β-catenin pathway in the absence of any WNT ligand.
DC21032 G 0507 G 0507 is a novel inhibitor of the bacterial LolCDE ABC transporter, binds to LolCDE and stimulates its ATPase activity.
DC21034 G 573 G 573 is a potent and selective, allosteric inhibitor of MEK with Ki of 0.3 nM.
DC11449 G0775 G0775 is a Synethetic analogs of arylomycins.
DC24027 STING Agonist-1(G-10) Featured G10 (STING Agonist 1) is a novel human-specific STING agonist.
DC12300 G3-C12 TFA G3-C12 (TFA) is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins.
DC22548 G-5555 G-5555 is a potent and selective PAK1 inhibitor (Ki=3.7 nM).

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