DC23729 |
FR-901464
Featured
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FR-901464 is a potent antitumor natural product that binds to the splicing factor 3b (SF3b) complex and inhibits pre-mRNA splicing, inhibits cell cycle progression at G1 and G2/M phases.. |
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DC8631 |
Framycetin sulphate |
Framycetin sulphate |
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DC8003 |
FRAX-486
Featured
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FRAX486 is a selective inhibitor of group I PAKs with IC50s of 8.25/39.5, /55.3 nM for PAK1/PAK2/PAK3 respectivelt; less potent for PAK4(IC50=779 nM). |
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DCQ-033 |
fraxin |
Fraxin is a coumarin glycoside that has been found in Fraxinus and has anti-inflammatory activity. |
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DC23050 |
fraxinellone
Featured
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Fraxinellone is a selective blocker of voltage-dependent Ca2+ channel, which possesses antimicrobial, anti-inflammatory, neuroprotective and vasorelaxing activities. |
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DC9344 |
Frentizole |
Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction.
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DC20208 |
Frovatriptan Succinate |
Frovatriptan Succinate is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors. |
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DC21026 |
FSC 231 |
FSC 231 (FSC231) is the first, cell-permeable small-molecule inhibitor of PICK1 PDZ domain with Kd of 10.1 uM. |
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DC23388 |
FT-001 |
FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1. |
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DC20272 |
FT113
Featured
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FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. |
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DC22096 |
FT895 |
FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM). |
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DC11029 |
FTBMT
Featured
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FTBMT is a novel selective GPR52 agonist of GPR52, increases intracellular cAMP levels in CHO cells expressing human, mouse, or rat GPR52, with pEC50 of 7.03, 6.85, and 6.87M, respectively. |
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DC12537 |
FtsZ inhibitor C109 |
FtsZ inhibitor C109 (Compound 10126109) is a broad spectrum antibacterial compound that inhibits the cell division protein FtsZ, inhibits the FtsZ GTPase activity with IC50 of 8.2 uM. |
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DC12362 |
Fuchsine base monohydrochloride |
Fuchsine base (monohydrochloride) is a magenta dye, which is certified for use for acid-fast staining with carbol-fuchsin. |
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DCAPI1052 |
Fudosteine |
Fudosteine |
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DC11394 |
Fulacimstat(BAY 1142524)
Featured
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Fulacimstat(BAY 1142524) is a small molecule chymase inhibitor. |
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DC4200 |
Fulvestrant
Featured
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Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.094 nM. |
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DC8855 |
Fumagillin
Featured
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Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. |
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DCAPI1020 |
Fumalic acid (Ferulic acid)
Featured
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Fumalic acid (Ferulic acid) |
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DC21027 |
Fumosorinone |
Fumosorinone is a novel potent, selective protein tyrosine phosphatase SHP2 inhibitor with IC50 of 6.31 uM. |
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DC9069 |
Furosemide |
Furosemide (Lasix) is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema. |
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DC10240 |
Fusidate Sodium |
Fusidate Sodium is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections. |
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DC21792 |
FV-100 |
FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.. |
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DC21031 |
FzM1.8 |
FzM1.8 is a small molecule, allosteric agonist of the Frizzled receptor Fzd4 with pEC50 of 6.4, potentiates β-catenin pathway in the absence of any WNT ligand. |
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DC21032 |
G 0507 |
G 0507 is a novel inhibitor of the bacterial LolCDE ABC transporter, binds to LolCDE and stimulates its ATPase activity. |
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DC21034 |
G 573 |
G 573 is a potent and selective, allosteric inhibitor of MEK with Ki of 0.3 nM. |
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DC11449 |
G0775 |
G0775 is a Synethetic analogs of arylomycins. |
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DC24027 |
STING Agonist-1(G-10)
Featured
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G10 (STING Agonist 1) is a novel human-specific STING agonist. |
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DC12300 |
G3-C12 TFA |
G3-C12 (TFA) is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. |
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DC22548 |
G-5555 |
G-5555 is a potent and selective PAK1 inhibitor (Ki=3.7 nM). |
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