| DC7766 |
Ravoxertinib
Featured
|
GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1. |
|
| DC22324 |
GDP366
Featured
|
GDP366, a dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. |
|
| DC10667 |
Gea3162
Featured
|
Gea 3162 is a potent inhibitor of ADP-induced platelet aggregation in platelet rich plasma (PRP). GEA 3162 stimulates cGMP production in platelets, granulocytes, and polymorphonuclear leukocytes. |
|
| DC12394 |
Gemcabene calcium |
Gemcabene (PD-72953, PD72953) is a first-in-class lipid-lowering agent and activator of PARP. |
|
| DC12392 |
Gemcabene
Featured
|
Gemcabene (PD-72953, PD72953) is a first-in-class lipid-lowering agent and activator of PARP. |
|
| DC8487 |
Gemcitabine elaidate
Featured
|
Gemcitabine elaidate is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. |
|
| DC2107 |
Gemcitabine HCl (Gemzar,LY188011)
Featured
|
Gemcitabine Hydrochloride (Gemzar) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively,showed potent activity against COVID-19(SARS-COV-2) with EC50 MERS-COV(1.216), SARS-COV(4.9 |
|
| DC10590 |
Gemcitabine monophosphate
Featured
|
Gemcitabine monophosphate disodium salt, also called GemMP, is a monophosphate derivative of Gemcitabine. |
|
| DCAPI1135 |
Gemfibrozil (Lopid) |
Gemfibrozil (Lopid) |
|
| DC3159 |
Gemifioxacin
Featured
|
Gemifloxacin mesylate (trade name Factive, Oscient Pharmaceuticals) is an oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. |
|
| DCAPI1307 |
Genipin |
Genipin |
|
| DCAPI1129 |
Geniposide |
Geniposide |
|
| DCAPI1139 |
Geniposidic acid |
Geniposidic acid |
|
| DC2092 |
Genistein
Featured
|
Genistein is a highly specific inhibitor of protein tyrosine kinase (PTK). |
|
| DC2093 |
Genistin
Featured
|
Genistin is an isoflavone glycoside found in soy-based products. Can be used as a negative control for the PTK inhibitor Genistein |
|
| DCAPI1064 |
mixtures of three isomers (Gentamicins C1, C2, and C1(subA).
Featured
|
Gentamycin sulfate (Gentacycol) |
|
| DC7417 |
Genz-123346
Featured
|
Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM. |
|
| DC12339 |
Geraniin |
Geraniin is a TNF-α releasing inhibitor with numerous activities including anticancer, anti-inflammatory, and anti-hyperglycemic activities, with an IC50 of 43 μM. |
|
| DCAPI1563 |
Teprenone |
Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as hypoxic/ischemic brain injury, inflammatory bowel disease and spinal and bulbar muscul |
|
| DC20390 |
Gerfelin |
Gerfelin is an osteoclastogenesis inhibitor (IC50=61 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.15 uM. |
|
| DC9606 |
Gestodene |
Gestodene(SHB 331;WL 70) is a progestogen hormonal contraceptive.
|
|
| DC21043 |
GGTI 2417
Featured
|
GGTI 2417 is the methyl ester prodrug of GGTI-2418, a highly potent, competitive, and selective inhibitor of GGTase I. |
|
| DC21044 |
GGTI 2418
Featured
|
GGTI 2418 (PTX 100) is a highly potent, competitive, and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTI) with IC50 of 9.5 nM, displays 5,600-fold selectivity over FTase. |
|
| DC21045 |
GGTI 2418 sodium |
GGTI 2418 sodium (PTX 100) is a highly potent, competitive, and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTI) with IC50 of 9.5 nM, displays 5,600-fold selectivity over FTase. |
|
| DC7784 |
GGTI-2133 |
GGTI-2133 is a potent and selective GGTase I inhibitor |
|
| DC21042 |
GGTI-2147
Featured
|
GGTI-2147 is a non-thiol peptidomimetic that inhibits GGTase I and blocks geranyl-geranylation of Rap1A (IC50=0.5 uM). |
|
| DC21047 |
GGTI-286 dihydrochloride |
GGTI-286 is a CAAX peptidomimetic that is a potent, cell-permeable, and selective inhibitor of GGTase I with IC50 of 2 uM, 25-fold more potent than FTI-277. |
|
| DC21046 |
GGTI-286 |
GGTI-286 is a CAAX peptidomimetic, potent, cell-permeable, and selective inhibitor of GGTase I with IC50 of 2 uM, 25-fold more potent than FTI-277. |
|
| DC7133 |
GGTI-DU40 |
GGTI-DU40 is highly selective inhibitor for GGTase-I both in vitro and in living cells. Studies indicate GGTI-DU40 blocks prenylation of a number of geranylgeranylated CaaX proteins. Treatment of MDA-MB-231 breast cancer cells with GGTI-DU40 inhibited thr |
|
| DC8873 |
GHRP-2 Acetate |
GHRP-2 is a synthetic hexapeptide Growth Hormone Releasing Peptide (GHRP), which acts on the hypothalamus and the pituitary gland to release growth hormone with a slight stimulator effect on Prolactin, ACTH and Cortisol levels. |
|
