| DC12562 |
LEM-14
Featured
|
LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3.. |
|
| DC12563 |
LEM-14-1189 |
LEM-14-1189 is a LEM-14 derivative that differentially inhibits the NSDs with in vitro IC50 of 418 μM (NSD1), IC50 of 111 μM (NSD2) and IC50 of 60 μM (NSD3).. |
|
| DCAPI1502 |
Lenalidomide
Featured
|
Lenalidomide is a thalidomide analog known to display TNF-α secretion inhibition and possesses immunomodulatory properties. |
|
| DC22302 |
Leonurine hydrochloride
Featured
|
Leonurine hydrochloride is an alkaloid isolated from Herba leonuri, with anti-oxidative and anti-inflammatory. |
|
| DC23882 |
LEQ 506 |
LEQ 506 (NPV-LEQ 506) is a second-generation inhibitor of Smoothened (Smo) with IC50 of 2 nM and 4 nM for human and mouse Smo, respectively. |
|
| DC9186 |
Lercanidipine HCl |
Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class. |
|
| DC8905 |
Lercanidipine
Featured
|
Lercanidipine is a calcium channel blocker of the dihydropyridine class. |
|
| DC5052 |
Lersivirine（UK 453061）
Featured
|
Lersivirine (UK-453061) is a next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for the treatment of HIV-1 infection. |
|
| DC8731 |
Lesinurad sodium
Featured
|
Lesinurad sodium (RDEA594 sodium) is an once-daily inhibitor of URAT1; URAT1 is a transporter in the kidney that regulates uric acid excretion from the body. |
|
| DC7631 |
Lesinurad (RDEA594）
Featured
|
Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney that regulates uric acid excretion from the body. |
|
| DC23569 |
Lesogaberan |
Lesogaberan (AZD-3355) is a potent, selective, peripherally acting GABAB receptor agonist with Ki of 5 nM and EC50 of 8.6 nM, 274-fold selectivity over GABAA (Ki=1.4 uM). |
|
| DC22807 |
Lestaurtinib
Featured
|
Lestaurtinib (KT-5555, CEP-701) is a potent, orally active JAK2, FLT3 and TrkA inhibitor with IC50 of 0.9 nM, 3 nM and < 25 nM, respectively. |
|
| DC21731 |
Letaxaban |
Letaxaban (TAK-442, TAK442) is a potent, selective and direct factor Xa (FXa) inhibitor with Ki of 1.8 nM for hFXa, >440-fold selectivity than thrombin and negligible effects on trypsin, plasmin, and tPA. |
|
| DC9798 |
Leteprinim
Featured
|
Leteprinim (Neotrofin, AIT-082) is a hypoxanthine derivative drug with neuroprotective and nootropic effects. |
|
| DC12543 |
Lethal toxin inhibitor DN1 |
Lethal toxin inhibitor DN1 is a small molecule that reduces the cytotoxicity of anthrax lethal toxin (LT) an inhibitor of LT-induced pyroptosis, acts as an antagonist of GPCR receptors type-1 angiotensin II receptor (AGTR1) and apelin receptor (APLNR) wit |
|
| DCAPI1414 |
Letrozole
Featured
|
Letrozole(CGS-20267) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant. |
|
| DC20434 |
Leucettamine B |
Leucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).. |
|
| DC9167 |
Calcium Folinate |
Leucovorin Calcium is a reduced folic acid. |
|
| DC8314 |
Leuprolide Acetate
Featured
|
Leuprolide acetate (Leuprorelin) is a GnRH analog; leuprolide acetate acts as an agonist at pituitary GnRH receptors. |
|
| DC22504 |
Leuprorelin
Featured
|
Leuprorelin (Leuprolide) is a GnRH analog and agonist of GnRH receptor, interrupts the normal pulsatile stimulation and desensitizing of the GnRH receptors.. |
|
| DCAPI1088 |
Levamisole HCl(Ergamisol) |
Levamisole HCl(Ergamisol) |
|
| DCAPI1004 |
Levetiracetam |
Levetiracetam |
|
| DCAPI1518 |
Levobupivacaine HCL |
Levobupivacaine HCL |
|
| DCAPI1002 |
Levofloxacin (Levaquin) |
Levofloxacin (Levaquin) |
|
| DC10257 |
Levofloxacin hydrate |
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. |
|
| DCAPI1348 |
Levonorgestrel(Levonelle) |
Levonorgestrel(Levonelle) |
|
| DCAPI1068 |
Levosimendan |
Levosimendan |
|
| DC9075 |
Levosulpiride |
Levosulpiride is the (S)-enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic drug of the benzamide class. |
|
| DC22727 |
LGB-321 |
LGB-321 (LGB321) is a potent and specific pan-Pim inhibitor with Ki of 1/2.1/0.8 pM for Pim1/2/3, respectively. |
|
| DC22137 |
LGD2226
Featured
|
LGD-2226 (LGD2226) is an orally active, selective androgen receptor modulator (SARM) with binding Ki of 1 nM, >1000-fold selectivity over GR,PR, MR and ER. |
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