| DC9693 |
Madrasin
Featured
|
Madrasin inhibits pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA. |
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| DC8125 |
ETH 4030(Magnesium ionophore III)
Featured
|
Magnesium ionophore III is an onophore used in solvent polymeric membrane electrodes for the assay of Mg2+ activities in blood serum in vitro. |
|
| DC11215 |
MAI-150 |
MAI-150 is a peptidomimetic inhibitor of APC-Asef interaction, blocks colorectal cancer migration.. |
|
| DC11201 |
MAI-400 |
MAI-400 (MAI400) is a novel peptide inhibitor of APC-Asef interaction with Kd of 12 nM and IC50 of 0.25 uM. |
|
| DC23792 |
MAL3-101 |
MAL3-101 is a Hsc70 modulator that inhibits Hsp70 ATPase activity, exhibits antiproliferative activity in breast cancer cells SK-BR-3 with IC50 of 27 uM. |
|
| DC22143 |
MALAT1-IN-1
Featured
|
MALAT1 inhibitor 5 (Malat1 inhibitor 5) is a selective small molecule targeting of Metastasis-associated lung adenocarcinoma transcript 1 (Malat1/MALAT1 mouse/human), a highly conserved long non-coding RNA; does not affect Neat1 lncRNA levels. |
|
| DC12536 |
Malic Enzyme inhibitor ME1
Featured
|
Malic Enzyme inhibitor ME1 (ME1) is a small molecule inhibitor of Malic Enzyme (ME1) with IC50 of 0.15 uM, suppresses growth of human CRC cells in vitro, with little effect on normal rat intestinal epithelial cells.. |
|
| DCAPI1277 |
Malotilate |
Malotilate |
|
| DC20141 |
Maltitol
Featured
|
Maltitol is a sugar alcohol used as a sugar substitute. It has 75-90% of the sweetness of sucrose (table sugar) and nearly identical properties. Maltitol may also be used as a plasticizer in gelatin capsules, as an emollient, and as a humectant. |
|
| DC12138 |
Maltohexaose (Amylohexaose) |
Maltohexaose is a natural saccharide, and can be produced from amylose, amylopectin and whole starch. |
|
| DC12157 |
Maltopentaose (Maltopentose) |
Maltopentaose is the shortest chain oligosaccharide that can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin. |
|
| DC23814 |
MAP4K4-IN-17
Featured
|
MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933. |
|
| DC21916 |
MAP4K4-IN-37 |
MAP4K4-IN-37 is a potent, selective, orally active inhibitor of serine-threonine kinase MAP4K4 with IC50 of 0.4 nM. |
|
| DC20442 |
MAP4K4-IN-44 |
MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay, demonstrates favorable in vivo bioavailability in mouse.. |
|
| DC21857 |
Mapracorat |
Mapracorat (ZK 245186) is a potent, selective and non-steroid glucocorticoid receptor (GR) agonist with binding Ki of 1.9 nM. |
|
| DC4217 |
Maraviroc
Featured
|
Maraviroc (Selzentry, UK-427857, Celsentri) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM, respectively. |
|
| DC21269 |
Marbostat-100 |
Marbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM, displays >200-fold selectivity over HDAC1-5, and HDAC7-10. |
|
| DC8909 |
Maribavir
Featured
|
Maribavir(GW257406X; BW1263W94; 1263W94) inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97. |
|
| DC10639 |
Marinopyrrole A (Maritoclax) |
Marinopyrrole A (Maritoclax) is a selective Mcl-1 antagonist. It binds to Mcl-1, but not Bcl-XL, and targets Mcl-1 for proteasomal degradation. Maritoclax disrupts the interaction between Bim and Mcl-1 with an IC50 of 10.1 μM. |
|
| DC22297 |
Marmesin
Featured
|
Marmesin is a coumarin originally isolated from the mature bark of A. marmelos. |
|
| DC20883 |
Maropitant citrate |
Maropitant citrate (Cerenia) is a selective neurokinin 1 receptor (NK1) antagonist for prevention of vomiting due to motion sickness in dogs.. |
|
| DC20443 |
MARPIN |
MARPIN is a novel ATR-Chk1 pathway inhibitor that inhibits hydroxyurea (HU)-induced phosphorylation of Ser345 on Chk1 with IC50 of 7.7 uM. |
|
| DC10062 |
MBP146-78
Featured
|
MBP146-78 inhibits the growth of Eimeria spp. both in vitro and in vivo. |
|
| DC12094 |
MBQ-167 |
MBQ-167 is a dual Rac/Cdc42 inhibitor, with IC50s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively. |
|
| DC7193 |
MBX-2982
Featured
|
MBX-2982 is a selective, orally-available GPR119 agonist for the treatment of type 2 tiabetes. |
|
| DC10872 |
MBX-4132
Featured
|
MBX-4132 a trans translation inhibitor by binding to the bacterial ribosome. |
|
| DC21270 |
MC-1575 |
MC-1575 is a potent and selective class IIa HDAC inhibitor with IC50 of 440 nM for maize HD1-A, displays >70-fold selectivity over HD1-B. |
|
| DC12527 |
MC180295
Featured
|
MC180295 (MC-180295, MC 180295) is a novel potent, highly selective CDK9 inhibitor with IC50 of 5 nM, displays >22-fold selectivity over other CDKs. |
|
| DC23370 |
MC2884 |
MC2884 is a novel hybrid, dual HAT/EZH2 inhibitor with IC50 of 3.27, 8.35 and 4.56 uM for CBP, KAT5 and p300, respectively. |
|
| DC11358 |
CPP32 Fluorogenic Substrate III |
Mca-DEVDAPK(Dnp)-OH is a substrate for caspase-3. |
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