DC7170 |
Lucidin (NSC 30546) |
Lucidin (NSC 30546) is a natural component of Rubia tinctorum L. lucidin is mutagenic in bacteria and mammalian cells. |
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DC22596 |
LUF6000 |
LUF6000 is a potent, selective, positive allosteric modulator (enhancer) of human A3 adenosine receptor, enhance Emax but without affecting agonist potency. |
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DC23647 |
LUF7346
Featured
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LUF7346 is a novel hERG allosteric modulator that slows IKr deactivation and positively shifting IKr inactivation. |
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DC8611 |
Luliconazole
Featured
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Luliconazole(NND 502) is an azole antifungal indicated for the topical treatment of interdigital tinea pedis. |
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DC22906 |
Lumateperone
Featured
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Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM). |
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DC20271 |
LUT014
Featured
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LUT014 is a novel BRAF agonist. |
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DC12120 |
Luteolin-7-rutinoside |
Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection. |
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DC23133 |
LX-1031 |
LX-1031 is a potent, orally active tryptophan 5-hydroxylase (TPH) inhibitor with potency of 10-100 nM, reduces 5-HT synthesis peripherally. |
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DC21251 |
LX-2931 |
LX-2931 (LX2931) is a potent, selective and orally bioavailable S1P lyase (S1PL) inhibitor. |
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DC23136 |
LX7101 |
LX7101 is a potent, dual LIMK and ROCK inhibitor with IC50 of 4.3/32//69/32/ nM for LIMK2/LIMK1/ROCK1/ROCK2, respectively. |
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DC26012 |
LXS-196
Featured
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LXS196 is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. It can be used for the treatment of uveal melanoma. |
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DC21256 |
LY 2318912 |
LY 2318912 is a potent, competitive, small molecule inhibitor of anandamide uptake with IC50 of 7.27 nM, shows high affinity against anandamide transporter binding site with Kd o f7.62 nM. |
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DC8602 |
LY311727
Featured
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LY 311727 is a specific group II sPLA2 (phospholipase A2 (PLA2)) inhibitor which has been reported to attenuate VEGF-mediated platelet-activating factor (PAF) synthesis in HUVEC and BAEC cells. |
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DC23633 |
LY 392098 |
LY 392098 is a selective, potent and centrally active positive allosteric modulator of AMPAR. |
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DC7944 |
LY2090314
Featured
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LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50s of 1.5 nM and 0.9 nM for GSK-3α and GSK-3β respectively. |
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DC12130 |
LY223982 |
LY223982 is a potent and specific inhibitor of leukotriene B4 receptor, with an IC50 of 13.2 nM against [3H]LTB4 binding to LTB4 receptor. |
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DC9304 |
LY2334737
Featured
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LY2334737 is an orally available prodrug of gemcitabine which is a nucleoside analog used as chemotherapy. |
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DC9975 |
Ly 2365109 Hydrochloride;n-[2-[4-(1,3-benzodioxol-5-yl)-2-(1,1-dimethylethyl)phenoxy]ethyl]-n-methylglycinehydrochloride
Featured
|
LY2365109 is a potent and selective GlyT1 inhibitors with IC50 value of 15.8 nM. |
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DC23720 |
LY2452473
Featured
|
LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM). |
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DC24072 |
LY-2584702 free base
Featured
|
LY2584702 is a potent, selective, ATP-competitive inhibitor of P70 S6 kinase-1 (p70S6K1) with IC50 of 4 nM. |
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DC24073 |
LY-2584702 hydrochloride
Featured
|
LY2584702 is a potent, selective, ATP-competitive inhibitor of P70S6 kinase-1 (p70S6K1) with IC50 of 4 nM. |
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DC7458 |
LY2608204
Featured
|
LY2608204 is a activator of glucokinase (GK) with EC50 of 42 nM. |
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DC22140 |
LY2623091 |
LY2623091 (LY-2623091) is an orally administered mineralocorticoid receptor antagonist for the treatment of essential hypertension and chronic kidney disease.. |
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DC23444 |
LY2624803 |
LY2624803 is a novel potent histamine H1 and 5HT-2A receptor modulator in the pipeline for treating insomnia.. |
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DC23510 |
LY2794193
Featured
|
LY2794193 is a highly potent and selective mGlu3 receptor agonist with Ki of 0.93 nM and EC50 of 47 nM, >100-fold selectivity over mGlu2 receptor.. |
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DC10815 |
LY2795050
Featured
|
LY2795050 is a novel selective κ-opioid Receptor (KOR) antagonist (IC50=0.72 nM) and has the potential as a PET tracer to image KOR in vivo. |
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DC7035 |
Merestinib(LY2801653 dihydrochloride)
Featured
|
LY2801653 2HCl is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM). |
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DC8586 |
LY2801653
Featured
|
LY2801653 is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM). |
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DC22595 |
LY2857785 |
LY2857785 is a potenrt, reversible and ATP-competitive CDK9 inhibitor with IC50 of 11 nM, also inhibits CDK8 (IC50=16 nM) and weakly inhibits CSK7 (IC50=246 nM). |
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DC22312 |
LY2940094
Featured
|
LY2940094 is a potent and selective nociceptin receptor antagonist which inhibits excessive feeding behavior in rodents. |
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