| DC22506 |
Merck60
Featured
|
Merck60 (BRD 6929, Compound-60) is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively. |
|
| DCAPI1395 |
Meropenem |
Meropenem |
|
| DC20130 |
meso-Erythritol
Featured
|
meso-Erythritol is a sugar alcohol that occurs naturally in a variety of foods (e.g., pear, watermelon), is 60-80% as sweet as sucrose, and is an approved low-calorie sweetener food additive. |
|
| DCAPI1322 |
Mestranol |
Mestranol |
|
| DC12327 |
Metadoxine |
Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway. |
|
| DC22157 |
Metarrestin
Featured
|
Metarrestin (ML246) is a specific inhibitor of perinuclear compartment (PNC), disrupts PNCs in PC3M-GFP-PTB cells with IC50 of 0.39 uM, specifically binds eEF1A2. |
|
| DC9563 |
Metaxalone |
Metaxalone(AHR438;NSC170959) is a muscle relaxant used to relax muscles.
|
|
| DC23326 |
Metesind glucuronate |
Metesind glucuronate (AG 331. |
|
| DCAPI1018 |
Metformin HCl(Glucophage) |
Metformin HCl(Glucophage) |
|
| DCAPI1174 |
Methacycline HCl (Physiomycine) |
Methacycline HCl (Physiomycine) |
|
| DC12309 |
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) |
MethADP is a specific CD73 inhibitor. |
|
| DC8943 |
Methimazole |
Methimazole(Tapazole, Northyx) is an antithyroid medicine. |
|
| DC8989 |
Methocarbamol |
Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. |
|
| DC9149 |
Methotrexate |
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. |
|
| DC23215 |
Methoxy-PEPy |
Methoxy-PEPy is a potent, selective mGlu5 receptor antagonist with IC50 of 1 nM. |
|
| DC10575 |
Methyl 13-cis-4-Oxoretinoate
Featured
|
Methyl 13-cis-4-Oxoretinoate is a bioactive chemical. |
|
| DC20131 |
Methyl 3,4-dihydroxybenzoate
Featured
|
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect. |
|
| DC8616 |
S-(5'-Adenosyl)-L-methionine chloride（SAM）
Featured
|
Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). |
|
| DC20447 |
Methyl Gerfelin |
Methyl Gerfelin (M-GFN) is an osteoclastogenesis inhibitor (IC50=2.8 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.23 uM. |
|
| DC20448 |
Methyliodobikinin |
Methyliodobikinin is a potent bikinin-like inhibitor targeting GSK3/Shaggy-like kinase, shows improved cell permeability, highly potent in vivo although it had lower activity in vitro. |
|
| DCAPI1359 |
Methylprednisolone |
Methylprednisolone |
|
| DC9417 |
Methylproamine |
Methylproamine is a DNA-binding radioprotector which, on the basis of published pulse radiolysis studies, acts by repair of transient radiation-induced oxidative species on DNA.
|
|
| DC20015 |
Metixene hydrochloride hydrate |
Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM. |
|
| DCAPI1095 |
Metolazone (Zaroxolyn) |
Metolazone (Zaroxolyn) |
|
| DC20191 |
Metronidazole Benzoate;Benzoyl metronidazole |
Metronidazole Benzoate is the benzoate ester of metronidazole, a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. |
|
| DC23468 |
MF266-1 |
MF266-1 is a potent, selective prostaglandin E receptor subtype 1 (EP1) antagonist with Ki of 3.8 nM, displayes a relatively good selectivity over other prostanoid receptors.. |
|
| DC22145 |
MF-766
Featured
|
MF-766 (MF766) is a highly potent and selective EP(4) antagonist with binding Ki of 0.23 nM, displays no significant affinity (>7000-fold selectivity) against other PG receptors (IC50>1500 nM); behaved as a full antagonist with an IC50 of 1.4 nM (shifted to 1.8 nM in the presence of 10% HS) in the functional assay; exhibits blockade of inhibition of TNFa-induced IP10 release by the specific EP4 agonist L-000902688 (IC50=9.5 nM); demonstrates potency and efficacy of in the rat AIA model measuring inhibition of paw swelling. |
|
| DC23707 |
MFA-1 |
MFA-1 (Merck FXR agonist 1) is a potent, synthetic FXR agonist with EC50 of 16.9 nM in coactivator recruitment assays, displays 500-fold more potent than CDCA. |
|
| DC11211 |
MFN2 agonist B-A l |
MFN2 agonist B-A/l is a mall-molecule mimics of the peptide-peptide interface of MFN2, allosterically activates MFN2 and promotes mitochondrial fusion with EC50 of 3 nM. |
|
| DC21918 |
MGR1 |
MGR1 is a ROS-generating probe that can generate ROS (reactive oxygen species) in different mammalian cells, causes concentration-dependent cell death in HEK293T with IC50 of 5.7 uM.. |
|
