| DC8234 |
PNRI-299 |
PNRI-299 is an inhibitor of activator protein-1 (AP-1) transcription (IC(50) of 20 microM) without affecting NF-kappaB transcription (up to 200 microM) or thioredoxin (up to 200 microM). |
|
| DC21521 |
PNU-112455A
Featured
|
PNU-112455A is an ATP-competitive CDK2/5 inhibitor with Ki of 2 uM and 2 uM for cdk2·GST-cyclin E and cdk5·GST-p25 respectively, shows no activity against c-c-Met, IGR-1R, and ERK2.. |
|
| DC10760 |
Pocapavir
Featured
|
Pocapavir is an investigational enterovirus (EV) capsid inhibitor. |
|
| DC6504 |
Patchouli Alcohol
Featured
|
Pogostemon (patchouli) leaves and their extracted oils are used in perfumes and in traditional medicine to relieve sunstroke, stop vomiting, and increase appetite. |
|
| DC26094 |
Poloppin II |
Poloppin II is an orally active, Poloppin derivative inhibitor of protein-protein interaction via the PBD of the mitotic Polo-like kinase (PLK) with IC50 of 41 uM in FP assays, exhibits IC50 of 61 nM cellular assay for mitotic arrest. |
|
| DC26116 |
Poloppin
Featured
|
Poloppin is a cell-active, small molecule inhibitor of protein-protein interaction via the Polo-box domain (PBD) of the mitotic Polo-like kinase (PLK) with IC50 of 26.9 uM (PLK1) in FP assays. |
|
| DCAPI1298 |
Polydatin(Piceid) |
Polydatin(Piceid) |
|
| DC10214 |
Polymyxin B sulphate
Featured
|
Polymyxin B is an antibiotic primarily used for resistant gram-negative infections. |
|
| DC22413 |
Pomaglumetad Methionil |
Pomaglumetad Methionil (LY2140023 monohydrate) is the methionine amide prodrug of the mGluR2/3 agonist LY-404039 with the potential oral treatment of schizophrenia.. |
|
| DC26122 |
Pomalidomide-C2-NH2 hydrochloride |
Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
| DC26126 |
Cereblon Ligand-Linker Conjugates 9(E3 Ligase Ligand-Linker Conjugates 2)
Featured
|
Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. |
|
| DC10829 |
Porcupine-IN-1
Featured
|
Porcupine-IN-1 is potent porcupine inhibitor with an IC50 of 0.5±0.2 nM. |
|
| DCAPI1336 |
Potassium iodide |
Potassium iodide |
|
| DC20217 |
Potassium thioacetate |
Potassium thioacetate is widely used as a sulfur source in the synthesis of sulfur-containing organic compounds. It has been employed for the synthesis of heterocycles, polymers, transition-metal ligands, nanoparticles, bioactive compounds and macromolecu |
|
| DC9213 |
GBR12783 |
Potent and selective DA uptake inhibitor |
|
| DC8603 |
SR 49059
Featured
|
Potent and selective non-peptide vasopressin V1A receptor antagonist; devoid of agonist activity. Displays high affinity and efficacy at both rat (KI=1.6 nM) and human (KI -1.1 - 6.3 nM) V1A receptors. |
|
| DC8590 |
CRT-0066101 hydrochloride
Featured
|
Potent inhibitor of protein kinase D (PKD); inhibits all PKD isoforms (IC50 values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively). |
|
| DC23003 |
hypocrellin A
Featured
|
Potent PKC inhibitor. Photosensitizing agent. Potent antileishmanial agent. |
|
| DC8484 |
KN-93(free base)
Featured
|
Potent, cell permeable inhibitor of CaM kinase II (IC50 = 0.37 μM). |
|
| DC24206 |
KN-93 HCl
Featured
|
Potent, cell permeable inhibitor of CaM kinase II (IC50 = 0.37 μM). |
|
| DC12421 |
PP1 inhibitor C31 |
PP1 inhibitor C31 is a 1E7-03 analog and protein phosphatase 1 (PP1) targeting small molecule with Kd of 1.88 uM, inhibits Ebola virus (EBOV) transcription and replication. |
|
| DC5007 |
pp1
Featured
|
PP1 is a potent and selective Src inhibitor for Lck/Fyn with IC50 of 5 nM/ 6 nM. |
|
| DC9931 |
PP2 analog
Featured
|
PP2 analog is the analog of PP2,a Src family kinase inhibitor. |
|
| DC5008 |
PP2(AGL 1879)
Featured
|
PP2 is Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM, ~100-fold less potent to EGFR, inactive for ZAP-70, JAK2 and PKA. |
|
| DC23712 |
PPARα activator compound 3 |
PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo. |
|
| DC23517 |
PPBI |
PPBI is a novel potent, selective, full M1 muscarinic agonist with EC50 of 5, 8, and 21 nM for human, rat, and mouse M1 receptors, respectively. |
|
| DC21525 |
PPI-2458 |
PPI-2458 is potent, specific, irreversible methionine aminopeptidase-2 (MetAP-2) inhibitor with IC50 of 0.2 nM, inhibits growth inhibition of HFLS-RA and HUVEC with IC50 of 0.04 nM. |
|
| DC21943 |
PPTN trifluoroacetate salt |
PPTN is a potent, highly specific amtagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays. |
|
| DC21942 |
PPTN |
PPTN is a potent, highly specific amtagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays. |
|
| DC22059 |
PptT inhibitor 8918 |
PptT inhibitor 8918 (Compound 8918) is a mycobactericidal amidino-urea compound that targets phosphopantetheinyl transferase (PptT, IC50=2.5 uM), shows an MIC90 of 3.1 uM against Mtb H37Rv. |
|
