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Cat. No. Product Name Field of Application Chemical Structure
DC33626 CPFX1302 CPFX1302 is a biochemical
DC33627 SEP-0371845 SEP-0371845 is a biochemical
DC33628 TP-4748 TP-4748 is a biochemical.
DC33629 TP748 TP748 is a bioactive chemical.
DC33630 ZN2007-RM1 ZN2007-RM1 is a bioactive chemical.
DC33632 CAY10594 Featured CAY10594 is a potent phospholipase D2 inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.
DC33637 RU-SKI43 HCl RU-SKI 43 is an inhibitor of Hat. It blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a. RU-SKI-43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR.
DC33638 CY5.5-COOH CY5.5 carboxylic acid, also known as Cyanine5.5 carboxylic acid, is a Far-red emitting fluorescent dye with Ex/Em wavelength 673nm/707nm. CY5.5 carboxylic acid can be considered non-reactive for most applications and used as a control or reference sample, and for instrument calibration.
DC33641 PSB-12054 PSB-12054 is a potent P2X4 receptor inhibitor. PSB-12054 has IC(50) of 0.189 μM and good selectivity versus the other human P2X receptor subtypes.
DC33643 ARC39 ARC39 is acid sphingomyelinase inhibitor (IC50 =20 nM).
DC33644 MC2050 HCl MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.
DC33645 TBK1/IKKε-IN-5 Featured QUN97653, also known as TBK1/IKKε-IN-5, is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively. QUN97653 was first reported in patent WO 2016049211. It has CAS#1893397-65-3 without code name. For the convenience of scientific communication, we temporally name it as QUN97653, which was based on Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).
DC33647 CM-4620 Featured CM-4620 is a calcium-release activated calcium-channel (CRAC channel) inhibitor, with IC50s of 119 nM, 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively.
DC33648 Hexakis(p-bromophenoxy)cyclotriphosphazene Featured LUN76721 has CAS#4376-72-1, is a cyclophosphazene and a useful chemical reagent. Cyclophosphazenes have been studied among others as flame retardant additives, high temperature fluids, clathrates, photostabilizers, or antioxidants in organic polymers. Cyclophosphazenes have also been used as phase transfer catalysts, as polypodants and cryptands. Cyclophosphazenes have also been successfully used as biologically active agents. Moreover cyclotriphosphazenes, were used for polymer functionalization and synthesis, as pendant groups or monomers for polyphosphazene synthesis, especially those bearing six chlorine atoms or phenoxy groups.
DC33649 Boc-Val-Cit-PAB Featured Boc-Val-Cit-PAB is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
DC33650 IUN76750 Featured UTL-5g is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hematotoxicity. It lowers elevated levels of AST, ALT, creatinine, BUN, and TNF-α, increases the reduced platelet count in mice, and acts as a novel chemo- and radioprotective agent.
DC33651 ML188 Featured ML188 is a Potent Noncovalent Small Molecule Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease. The X-ray structure of SARS-CoV 3CLpro bound with ML188 was instrumental in guiding subsequent rounds of chemistry optimiz
DC33652 LY-3381916 Featured LY-3381916, also known as IDO1-IN-5, is a potent, selective and brain penetrated DO1 inhibitor. LY3381916 specifically targets and binds to IDO1, a cytosolic enzyme responsible for the oxidation of the amino acid tryptophan into the immunosuppressive metabolite kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, LY3381916 restores and promotes the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, and T lymphocytes, and causes a reduction in tumor-associated regulatory T cells (Tregs).
DC33653 ML417 Featured ML417 is a Highly Selective D3 Dopamine Receptor Agonist. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein activation, and ERK1/2 phosphorylation (pERK) while lacking activity at other dopamine receptors. Screening of ML417 against multiple G protein-coupled receptors revealed exceptional global selectivity. Molecular modeling suggests that ML417 interacts with the D3R in a unique manner, possibly explaining its remarkable selectivity. ML417 was also found to protect against neurodegeneration of dopaminergic neurons derived from iPSCs.
DC33654 Fentin Fentin is an organotin compound (OTC) widely used as an agricultural fungicide and miticide.
DC33655 Methyldymron Methyldymron is a bioactive chemical.
DC33656 Noreximide Noreximide is a sedative.
DC33657 DNOC DNOC is an agricultural chemical.
DC33658 EINECS 206-113-3 Robinin is a flavone glycoside based on kaempferol.
DC33659 Arsicodile Sodium cacodylate is an arsenical that has been used as a dermatologic agent and as an herbicide.
DC33660 2-Naphthalenecarboxamide C.I. 37530 is a color developer.
DC33661 2-Naphthanilide 3-Hydroxy-3'-nitro-2-naphthanilide is a bioactive chemical.
DC33662 3-Cyclohexene-1-methanol Levomenol is found in fats and oils.
DC33663 Antibiotic BB-K 8 Amikacin is an aminoglycoside antibiotic derived from kanamycin A. Like other aminoglycosides, amikacin binds to bacterial ribosomes and disrupts translation.1 However, the specific binding sites differ between different aminoglycoside antibiotics, as do the mechanisms of resistance. Amikacin is effective against Gram-negative and Gram-positive bacteria.
DC33664 Bekanamycin sulfate Bekanamycin sulfate is a bioactive chemical.

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