| DC34027 |
5NAA |
5NAA is a nitroaromatic compound. 5NAA is a molecule secreted by Streptomyces scabies, the plant pathogen responsible for potato scab. 5NAA is also the starting material for synthetic dyes and other nitroaromatic compounds. |
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| DC34028 |
UDCA sodium |
Ursodeoxycholate sodium, also known as Ursodeoxycholic Acid (sodium salt) and UDCA sodium, has anti-inflammatory and cytoprotective properties. UDCA sodium is a naturally occurring secondary bile acid. UDCA sodium is an FDA-approved drug for cholestatic liver disorders. |
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| DC34029 |
AA-5HT |
AA-5HT, also known as Arachidonoyl serotonin or N-arachidonoyl-serotonin, is an inhibitor of fatty acid amide hydrolase (FAAH). It has analgesic properties and acts as an antagonist of the TRPV1 receptor. It was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion. |
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| DC34030 |
Eicosapentaenoyl Serotonin |
Eicosapentaenoyl Serotonin is a dual fatty acid amide hydrolase (FAAH) and TRPV1 antagonist. |
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| DC34031 |
G-Glu-Val |
G-Glu-Val, also known as gamma-Glutamyl-L-valine or H-gGlu-Val-OH, is a taste-modulating dipeptide and a main contributor to the "kokumi" taste of edible beans. |
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| DC34032 |
4-Fluorophenylalanine |
4-Fluorophenylalanine, also known as (S)-4-Fluorophenylalanine, L-4-Fluorophenylalanine and p-fluorophenylalanine, inhibits mitosis and reversible arrests HeLa cells in G2 phase. |
|
| DC34033 |
U-0521 |
U-0521 is a catechol-O-methyltransferase (COMT) inhibitor. U-0521 enhances the availability and utilization of levodopa in the brain. |
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| DC34034 |
2-AEMP TFA |
2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA. |
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| DC34035 |
Myeloperoxidase Inhibitor 1 |
4-POBN is a potent and irreversible inhibitor of myeloperoxidase. |
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| DC34036 |
Desmetramadol |
Desmetramadol is a central analgesic drug candidate. Desmetramadol inhibits 5-hydroxytryptamine type 2C receptors expressed in Xenopus Oocytes. |
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| DC34037 |
RBI-257 Maleate |
RBI-257 Maleate is a highly potent dopamine D4 receptor-selective ligand. RBI-257 Maleate may be a useful probe or radioligand for brain dopamine D4 receptors. |
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| DC34038 |
Resorufin |
Resorufin, also known as OUL47 or NSC12097, is an ARTD10 inhibitor. Resorufin is widely used as an indicator of cell viability in assays. |
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| DC34039 |
Ibotenic Acid |
Ibotenic Acid is a potent excitatory amino acid agonist. Ibotenic Acid causes motor depression, ataxia, and changes in mood. Ibotenic Acid is also a neurotoxin. |
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| DC34040 |
Bicuculline methiodide |
Bicuculline methiodide is a GABA(A) receptor antagonist. Bicuculline methiodide attenuates inflammation by inhibiting the production of proinflammatory cytokines, such as tumor necrosis factor-alpha, and by increasing the production of the anti-inflammatory cytokine interleukin-10, both of which play important roles in the pathogenesis of sepsis. |
|
| DC34041 |
Inz-1 |
Inz-1 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. |
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| DC34042 |
UCL2077 |
UCL2077 is a selective slow-afterhyperpolarization (sAHP) channel blocker. UCL2077 suppresses the sAHP present in hippocampal neurons in culture and in the slice preparation. UCL2077 is selective and has minimal effects on Ca(2+) channels, action potentials, input resistance and the medium afterhyperpolarization. |
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| DC34044 |
Trimebutine Maleate |
Trimebutine Maleate is a drug with antimuscarinic and weak mu opioid agonist effects. Trimebutine Maleate modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome. Trimebutine Maleate is used for treatment of irritable bowel syndrome and other gastrointestinal disorders. |
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| DC34045 |
BIR2 |
BIR2 is a balloon inducing reagent. BIR2 triggers a spontaneous self-organizing program that leads to the formation of a 3-D balloon-shaped structure during hESC differentiation. |
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| DC34046 |
Nafronyl Oxalate |
Nafronyl Oxalate is a a selective antagonist of 5-HT2 receptors. Nafronyl Oxalate is a vasodilator used in the management of peripheral and cerebral vascular disorders. It is also claimed to enhance cellular oxidative capacity. |
|
| DC34047 |
NG-97 |
Aminopurvalanol A selectively inhibits TgCK1alpha. Aminopurvalanol A also acts as a cell-permeable cyclin-dependent kinase inhibitor, inhibiting cdk1/cyclin B, cdk2/cyclin A, cdk2/cyclin E, and cdk5/p35. |
|
| DC34048 |
CYM-5478
Featured
|
CYM-5478 is a potent, selective agonist for S1P2. Under nutrient-deprivation stress produced by serum-starvation, CYM-5478 induced a statistically significant increase in the viability of C6 cells in a dose dependent manner at concentrations above 100?nM. |
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| DC34049 |
BCA Disodium |
BCA Disodium, also known as Bicinchoninic Acid Sodium, is used for the determination of Cu and protein concentration in assays. |
|
| DC34050 |
DSHN
Featured
|
DSHN is a novel activator of small heterodimer partner (SHP, NR0B2). DSHN transcriptionally activates SHP mRNA, but also stabilizes the SHP protein by preventing its ubiquitination and degradation. |
|
| DC34051 |
Benomyl |
Benomyl is a is a fungicide. It is a systemic benzimidazole fungicide that is selectively toxic to microorganisms and invertebrates, especially earthworms. Benomyl binds to microtubules, interfering with cell functions, such as meiosis and intracellular transportation. The selective toxicity of benomyl as a fungicide is possibly due to its heightened effect on fungal rather than mammalian microtubules. |
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| DC34052 |
Mesosulfuron-methyl |
Mesosulfuron-methyl is a systemic herbicide used for post-emergence control of grasses and other weeds in cereals. |
|
| DC34053 |
SM-7368
Featured
|
SM-7368 inhibits TNF-alpha-induced MMP-9 upregulation in a concentration-dependent manner. SM-7368 strongly inhibits the TNF-alpha-induced invasion of HT1080 human fibrosarcoma cell line. |
|
| DC34054 |
PHPS1
Featured
|
PHPS1 is an inhibitor of the protein tyrosine phosphatase Shp2. PHPS1 also efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines. |
|
| DC34055 |
L-703606 Oxalate |
L-703606 Oxalate is a tachykinin NK1 receptor antagonist. |
|
| DC34056 |
Sophoridine hydrate |
Sophoridine is an antiviral against Coxsackievirus B3. Sophoridine works by regulating cytokine expression which may represent a potential therapeutic agent for viral myocarditis. Sophoridine also has anti-tumor and anti-inflammatory properties. |
|
| DC34057 |
NCGC607
Featured
|
NCGC607 is a a small-molecule noninhibitory chaperone of glucocerebrosidase. |
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