| DC34457 |
Nalmefene Hydrochloride |
Nalmefene HCl is an antagonist of the opioid receptors. |
|
| DC34458 |
EPPS |
EPPS is a rescuer of A? aggregation and behavioural deficits, binding to A? aggregates and converting them into monomers. |
|
| DC34459 |
ADP Sodium Salt |
ADP Sodium is an adenine nucleotide, converting into ATP by ATP synthases, affecting platelet activation through its interaction with P2Y1, P2Y12 and P2X1. |
|
| DC34460 |
C8 Ceramide |
C8 Ceramide is a cell-permeable analog of naturally occurring ceramides. |
|
| DC34461 |
IMB-10 |
IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo. |
|
| DC34462 |
PF-5274857 HCl |
PF-5274857 HCl is a potent and selective smoothened (Smo) receptor antagonist. |
|
| DC34463 |
Milbemycin A3 Oxime |
Milbemycin A3 Oxime is an opener of glutamate sensitive chloride channels in neurons of invertebrates, leading to paralysis by hyperpolarisation of these cells and blocking signal transfer. Milbemycin A3 Oxime is also an anthelmintic. Formulations containing milbemycin A3 oxime, in combination with milbemycin A4 oxime, have been used in the treatment of parasitic infections in dogs. |
|
| DC34464 |
SKI-II Hydrochloride |
SKI-II HCl is a substrate competitive, reversible, and highly specific inhibitor of sphingosine kinase. |
|
| DC34465 |
ACT-678689 |
ACT-678689 is a potent inhibitor of tryptophan hydroxylase 1 (TPH1). |
|
| DC34466 |
Toltrazuril |
Toltrazuril (Tol) is a broad-spectrum anticoccidiosis drug that is widely used in the prevention and treatment of coccidiosis infection in poultry and mammals. |
|
| DC34467 |
FAD-Na2 |
FAD-Na2 is a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. |
|
| DC34468 |
BLI-489 Hydrate |
BLI-489 Hydrate is a novel beta-lactamase inhibitor. |
|
| DC34469 |
Enbucrilate |
Enbucrilate is a tissue adhesive, forming polymer films at oil-water interfaces and revealing films of diverse morphology. |
|
| DC34471 |
GA3-AM |
GA3-AM is a cell permeable chemical dimerizer. |
|
| DC34472 |
LAP |
LAP is a photocrosslinker for hydrogels. |
|
| DC34473 |
TMRM |
TMRM is a sensitive fluorescent probe for mitochondrial membrane potential. |
|
| DC34474 |
FHZ |
FHZ is a highly selective, cell-permeable, non-cytotoxic probe for dual channel detection of (OH radical) and HOCl in live cells and zebrafish embryos. |
|
| DC34475 |
AalphaC |
AalphaC is a potential human carcinogen. |
|
| DC34476 |
MS0015203 |
MS0015203 is a potent and selective agonist of the neuropeptide receptor GPR171. |
|
| DC34477 |
Imidafenacin hydrochloride |
Imidafenacin HCl is a potent antimuscarinic agent, exhibiting selectivity toward muscarinic M3 receptors. |
|
| DC34478 |
ABC44 |
ABC44 is a potent and selective inhibitor of palmitoyl-protein thioesterase 1 (PPT-1). |
|
| DC34479 |
NSC-57969 |
NSC-57969 is a MDR-selective agent, exhibiting a robust Pgp-dependent toxic activity across diverse cancer cell lines. |
|
| DC34480 |
Cerebrosterol |
Cerebrosterol is a major brain metabolite of cholesterol. |
|
| DC34481 |
MitoNeoD |
MitoNeoD is a novel mitochondria-targeted O2(??) probe that can be used in vivo. It prevents DNA intercalation. MitoNeoD incorporates a carbon-deuterium bond, and enhances O2(??) selectivity. MitoNeoD comprises a O2?--sensitive reduced phenanthridinium moiety modified to prevent DNA intercalation, as well as a carbon-deuterium bond to enhance its selectivity for O2?- over non-specific oxidation, and a triphenylphosphonium lipophilic cation moiety leading to the rapid accumulation within mitochondria. MitoNeoD is a versatile and robust probe to assess changes in mitochondrial O2?- from isolated mitochondria to animal models, thus offering a way to examine the many roles of mitochondrial O2?- production in health and disease. |
|
| DC34482 |
Dihydroresveratrol
Featured
|
Dihydroresveratrol is an SIRT1 activator. It is a primary metabolite of resveratrol. |
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|
| DC34483 |
ATC0065 dihydrochloride |
ATC0065 dihydrochloride is a novel nonpeptidic and potent melanin-concentrating hormone receptor 1 (MCHR1) selective antagonist. |
|
| DC34484 |
ATC0175
Featured
|
ATC0175 is a novel nonpeptidic and orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist. |
|
| DC34485 |
Delphinidin Chloride |
Delphinidin Chloride is an inhibitor of BDNF-induced migration and invasion in SKOV3 ovarian cancer cells. |
|
| DC34486 |
Ac4ManNAz |
Ac4ManNAz is a novel probe for metabolic labeling of sialoglycans, selectively imaging polysialic acids in neurons. |
|
| DC34487 |
DBC |
DBC is a ubiquitous environmental pollutant, inducing significant DNA strand break levels and micronuclei in HepG2 cells. |
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