| DC34402 |
MB-3 |
MB-3 is a histone acetyltransferase GCN5 inhibitor. |
|
| DC34403 |
MSX-2 |
MSX-2 is a selective A2A adenosine receptor antagonist. |
|
| DC34404 |
MDL-12330A |
MDL-12330A is an inhibitor of adenylyl cyclase. It acts by inhibiting cAMP and cGMP phosphodiesterases and blocking slow extracellular and store-operated Ca2+ entry into cells. |
|
| DC34405 |
Necrostatin-7 |
Necrostatin-7 is a necroptosis inhibitor. It acts by inhibiting TNF-alpha-induced necroptosis in a FADD-deficient variant of human Jurkat T cells. |
|
| DC34406 |
T62 |
T62 is an allosteric enhancer of A1 adenosine receptor. |
|
| DC34407 |
FK-866 Hydrochloride
Featured
|
Daporinad, also known as APO-866 and FK866, is a small molecule with potential antineoplastic and antiangiogenic activities. NMPRTase inhibitor APO866 binds to and inhibits nicotinamide phosphoribosyltransferase (NMPRTase), inhibiting the biosynthesis of nicotinamide adenine dinucleotide (NAD+) from niacinamide (vitamin B3), which may deplete energy reserves in metabolically active tumor cells and induce tumor cell apoptosis. In addition, this agent may inhibit tumor cell prioduction of vascular endothelial growth factor (VEGF), resulting in the inhibition of tumor angiogenesis. |
|
| DC34408 |
EBPC |
EBPC is a potent aldose reductase inhibitor. |
|
| DC34409 |
8-Br-cGMP |
8-Br-cGMP is an activator of cGMP-dependent protein kinase. It acts by inhibiting the intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine. |
|
| DC34410 |
CX-6258 Hydrochloride
Featured
|
CX-6258 HCl is a potent, selective, and orally efficacious pan-Pim kinases inhibitor. |
|
| DC34411 |
SC-58125 |
SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor. |
|
| DC34412 |
MeBIO |
MeBIO is a negative control analog of BIO, and an aryl hydrocarbon receptor (AhR) agonist. It causes redistribution of AhR to the nucleus. |
|
| DC34413 |
Arg-Gly-Asp |
Arg-Gly-Asp is a primary sequence in cellular recognition. It is involved with the binding of proteins to cell surfaces and has strong affinity and selectivity to the alpha(V)beta(3) integrin receptors. |
|
| DC34414 |
U-99194 maleate |
U-99194 maleate is a potent, selective D3 antagonist. |
|
| DC34415 |
AM-404 |
AM-404 is a selective inhibitor of the carrier-mediated transport of anandamide without affecting anandamide hydrolysis. |
|
| DC34416 |
Cirazoline Hydrochloride |
Cirazoline HCl is a selective alpha1-adrenoceptor agonist and a non-selective imidazoline binding site ligand. |
|
| DC34417 |
Nor-SCH-12679 Maleate |
Nor-SCH-12679 Maleate is a D1-dopamine receptor antagonist. |
|
| DC34418 |
Muscimol Hydrobromide |
Muscimol HBr is a GABAA receptor agonist. |
|
| DC34419 |
NAEPA |
NAEPA is a selective lysophosphatidic acid-1 (LPA1) receptor agonist and a LPA mimetic. |
|
| DC34420 |
PQ1 Succinate |
PQ1 Succinate is a gap junction enhancer. It acts by restoring GJIC and increasing connexin expression in breast cancer cell lines while not affecting normal mammary cells. |
|
| DC34422 |
Pyr3 |
Pyr3 is a selective antagonist of the canonical transient receptor potential channel 3 (TRPC3). |
|
| DC34423 |
AC-93253 iodide |
AC-93253 iodide is a SIRT2 selective inhibitor. It acts by significantly enhancing acetylation of tubulin, p53, and histone H4. |
|
| DC34425 |
S3QEL-2 |
S3QEL-2 is a modulator of the retrograde signaling. It acts by strongly mitigating the oxidative stress-induced apoptosis that limits the yield of functional ?-cells from intact islets. |
|
| DC34426 |
2002-H20 |
2002-H20 is an inhibitior of Aβ42-induced cytotoxicity. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity. |
|
| DC34427 |
EIPA |
EIPA is a selective blocker of Na+/H+ antiport. |
|
| DC34428 |
A1899 |
A1899 is a potent and selective TASK-1 and TASK-3 antagonist. |
|
| DC34429 |
L-NMMA acetate |
L-NMMA acetate is an endothelium-derived relaxing factor inhibitor. It acts by inhibiting the generation of NO from arginine. |
|
| DC34432 |
Brilliant Blue G |
Brilliant Blue G is a P2X7 purinergic receptor antagonist. |
|
| DC34434 |
AZD7762 Hydrochloride |
AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and potentiating DNA-targeted therapies. |
|
| DC34435 |
Dicyclanil |
Dicyclanil is an insect growth regulator. |
|
| DC34436 |
XRP44X |
XRP44X is a potent Ras-Net (Elk-3) pathway inhibitor. |
|
