| DC47015 |
D-(+)-Fucose |
D-(+)-Fucose is a nonmetabolizable analogue of l-arabinose. D-(+)-Fucose prevents growth of Escherichia coli B/r on a mineral salts medium plus l-arabinose by inhibiting induction of the l-arabinose operon. D-fucose is a potent inducer of beta-methylgalactoside permease (MGP). |
|
| DC47016 |
Yadanzioside M |
Yadanzioside M is a natural compound with anti-cancer activity. |
|
| DC47020 |
Sophoramine |
Sophoramine ((-)-Sophoramine), an alkaloid, is a dehydro-derivative of Matrine. |
|
| DC47022 |
Quercetin 3,3'-dimethyl ether |
Quercetin 3,3'-dimethyl ether possesses antioxidant acticity. |
|
| DC47026 |
4-Phenyl-7,8-dihydroxycoumarin |
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative and can be used for bronchiectasiss research. |
|
| DC47047 |
Polθ-IN-1-d3 |
Polθ-IN-1-d3 (example 1) is a deuterated Polθ inhibitor used for cancer study (extracted from patent WO2021028670). |
|
| DC47060 |
Ansofaxine
Featured
|
Ansofaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for the research of depression. |
|
| DC47064 |
Hexasodium phytate |
Hexasodium phytate (Phytic acid hexasodium) is a phosphorus storage compound of seeds and cereal grains. Hexasodium phytate has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Hexasodium phytate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects. |
|
| DC47065 |
Idetrexed |
Idetrexed is a thymidylate synthase inhibitor specifically transported into alpha-folate receptor (alpha-FR)-overexpressing tumors. BGC 945 inhibited thymidylate synthase with a Ki of 1.2 nmol/L. |
|
| DC47075 |
Syringetin |
Syringetin, a flavonoid derivative, is associated with increased BMP-2 production. Syringetin stimulates osteoblast differentiation at various stages, from maturation to terminally differentiated osteoblasts. |
|
| DC47086 |
7,3′,4′-Tri-O-methyleriodictyol |
7,3′,4′-Tri-O-methyleriodictyol is a flavonoid with an antimutagenic activity. 7,3′,4′-Tri-O-methyleriodictyol inhibits the furylfuramide-induced SOS response and has potency as bioantimutagens. |
|
| DC47096 |
Umckalin |
Umckalin is a oxygenated coumarin from Pelargonium sidoides. |
|
| DC47105 |
Complanatoside B |
Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects. |
|
| DC47140 |
Yadanzioside K |
Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima. |
|
| DC47178 |
Mead acid |
Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency. |
|
| DC47179 |
Tyrosylleucine |
Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity. |
|
| DC47224 |
GPX4-IN-3 |
GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM. |
|
| DC47227 |
(−)-Myrtenal |
(−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats. |
|
| DC47243 |
Dehydroglyasperin C |
Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities. |
|
| DC47247 |
Tyrosylleucine TFA |
Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity. |
|
| DC47249 |
Piperitone |
Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity. |
|
| DC47250 |
Nonanal |
Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity. |
|
| DC47877 |
tri-GalNAc-COOH (acetylation)
Featured
|
tri-GalNAc-COOH acetylation is the acetylated and modified form of tri-GalNAc-COOH. tri-GalNAc-COOH acetylation can be used for the synthesis of LYTAC. |
|
| DC47950 |
MPO-IN-3 |
MPO-IN-3 is a potent myeloperoxidase (MPO) inhibitor (WO2013068875A1, example 191). Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the peroxidase superfamily. |
|
| DC47951 |
MPO-IN-1 |
MPO-IN-1 is a potent, orally active, and irreversible indole-containing inhibitor of myeloperoxidase (MPO). MPO-IN-1 has IC50s of 2.6 μM and 5.3 μM for MPO and thyroid peroxidase (TPO), respectively. MPO-IN-1 inhibits MPO activity in an acute mouse model of inflammation. |
|
| DC48076 |
MSDC-0602K Potassium |
MSDC-0602K is a insulin sensitizer that modulates the mitochondrial pyruvate carrier (MPC). |
|
| DC48377 |
DNPH1i(N6-benzyladenosine) |
DNPH1i (N6-benzyladenosine,BAPR) is a competitive inhibitor of adenosine deaminase(ADA) from L-1210 cells in axenic culture as well as a potent antiproliferative agent in vitro and in vivo. |
|
| DC48378 |
Zeaxanthin dipalmitate |
Zeaxanthin dipalmitate (Physalien) is a wolfberry-derived carotenoid, has anti-inflammatory and anti-oxidative stress effects. Zeaxanthin dipalmitate directly interact with p2X7 receptor (Kd=81.2 nM) and adiponectin receptor 1 (AdipoR1; Kd=533 nM) in a positive dose-dependent manner. Zeaxanthin dipalmitate restores mitochondrial autophagy functions suppressed by ethanol intoxication. Zeaxanthin dipalmitate can be used in the research of alcoholic fatty liver disease (AFLD) and retinitis pigmentosa (RP). |
|
| DC48390 |
CD73-IN-5 |
CD73-IN-5 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (IC50 = 19 nM). |
|
| DC48402 |
EAAT2 activator 1 |
EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2). EAAT2 is the major glutamate transporter and functions to remove glutamate from synapses. EAAT2 activator 1 increases EAAT2 protein levels dose-dependently. |
|
